Breast cancer is becoming a major health concern in most of the countries. Even though the exact cause of disease is unknown the count is only increasing steadily. Women those who have invasive breast cancer, underwent mastectomy and recurrent bouts of breast tumors should undergo a special serum test namely IHC-Estrogen-Receptor-Progesterone-Receptor (ERPR) blood test regularly. Thousands of women all over the world have done mastectomy and are undergoing chemotherapy regularly. These types of women should do what is known as ERPR blood test regularly. They can do it on their own or under medical supervision. Cancer cells can grow again and start destroying the good ones. People can rule out these types of recurrent growths when they undergo this blood test.