Anomalies of the CVJ (craniovertebral conjunction) may be congenital or acquired.It is a junction and a transition zone between a mobile cranium & spinal column. Brain MRI shows the presence of a very rare complex CVJ malformation. Clinical findings may include muscle weakness, respiratory insufficiency, vascular abnormalities, low bone mineral density and higher risk of developing osteoporosis. Some of the anomalies of the CVJ are: Trauma to the bones or the supporting ligaments of the CVJ, Inflammatory (rheumatoid arthritis, ankylosing spondylitis), and Genetic syndromes like Down syndrome.