The edible oyster belongs to two types, Ostrea, and Crassostrea. Oyster takes a time period of 18 months to five years to develop to be a market size Oyster. Oyster has been termed as both ingested and occupational allergen. Oysters are eaten raw, cooked or even smoked. Apart from this oyster is also used for the preparation of sauce. The allergy caused due to Oyster a type of shellfish is checked using the lge blood test. Traditionally, Skin prick method which was quite painful was used for testing purpose. Some common antigenic structures are shown by the oyster exposure.