Alpha 1 Antitrypsin is indeed a vital protein from the serpin superfamily and is first described by Laurell and Eriksson in the year 1963. This protein is originally encoded by the Serpina1 gene of the human DNA. Alpha-1 antitrypsin (AAT) can be highly helpful in identifying alpha-1 antitrypsin deficiency and whether it’s the cause of the chronic obstructive pulmonary disease (COPD) at cases when the person is free from certain risk factors like smoking, exposure to fumes, dust and certain other similar conditions.