BRAF V600E Mutations refer to specific changes/mutations in the gene of BRAF, which is responsible for the formation of a protein that plays an important role to send signals in various cells and help in the growth of a cell. BRAF gene mutation may sometimes found in a few types of cancer, such as colorectal and melanoma cancers. It may even increase the spread/growth of various cancer cells. Hence, BRAF V600E Mutations tests in tumor tissues help doctors to formulate good plans for effective cancer treatment.