H. pylori is thought to infect about half of the overall world population. Helicobacter pylori is known to be a primary cause of peptic ulcer disease. H. pylori is an important cause of particular diseases of the upper gastrointestinal tract. It might also be transmitted orally by way of fecal matter through the ingestion of waste-tainted water, thus a hygienic environment might help decrease the danger of H. pylori infection. Left untreated, H. pylori generally stays in the stomach throughout the life span of the person. It is contagious, although the precise route of transmission isn't known. It hasn't been shown whether eradication of H. pylori would reduce the incidence of gastric cancer in these types of patients. Hence the IgG antibody against H. Pylori test needs to be done to check as well as determine the primary causes for ulcers in the anterior and posterior part of the stomach and duodenum. In this artifact we are going to discuss about the major facts related to IgG antibodies against H. Pylori.