If you are experiencing sudden redness in the skin, itchy sensation, coupled with inflammation of the joints, as well as calcification, chances are that you may have scleroderma, which is a serious condition as it can affect many areas of your body. You need to consult your physician right away who would recommend a series of tests, including the SCL 70 Antibody Serum test to confirm sclerosis. This test is generally part of a second tier of tests, which is often conducted after the initial prognosis has been confirmed. Your doctor would recommend that you take this test to further confirm the diagnosis of Scleroderma, as well as use the same to monitor the effectiveness of the treatment provided.