The scrub-typhus IgM test is a test that is used for the detection of scrub typhus transmitted to humans through the bite of the larva of trombiculid mites or through the bacteria Orientia tsutsugamushi .The bite results in the formation of an eschar or a scab at the site. The highly infectious disease is common in areas with scrub vegetation and unavailability of immediate treatment can be fatal. The test is carried out by immunofluorescence assay (IFA) for testing IgM antibodies. A Rapid test with the help of a substrate is also often carried out before the IFA. The IFA is done to confirm the presence of the above antibody bound to the scrub-typhus antigen which is called a serological test and usually done after the Rapid test.