Allergen-specific Immunoglobulin E (IgE) blood test uses a small blood sample to determine if a person is allergic to Dog Dander. Dander consists of small particles and dead skin cells shed by cats, dogs, birds and other animals with fur or feathers. These microscopic bits of skin can cause reactions in people who are allergic to these triggers. Dander can remain in clothing and bedding until it is thoroughly cleaned. Dog dander is a very common allergy. It causes itchiness in the skin, watery eyes or form rashes. A more serious dog dander allergic reactions can lead to respiratory problems like difficulty in breathing or asthma.