Isocynate is used primarily as starting materials in a variety of manufacturing processes, including the production of plastics, polyurethane, foams and electrical wire insulation. They are also common components of paints and other durable and protective finishes, adhesives, elastomers in automobile bumpers, printing rolls and coated fabrics. Exposure to these during work is very common in these specific industries, and it can occur at any stage from the initial manufacturer of the isocyanates to their final use in other production processes. It can cause chemical bronchitis, laryngitis and chest pain, and severe asthma.