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लेप्टोस्पायरोसिस - लक्षण, उपचार और कारण

लेप्टोस्पायरोसिस क्या है? इलाज लक्षण

लेप्टोस्पायरोसिस क्या है?

जीनस से संबंधित रोगजनक सर्पोकेट्स लेप्टोस्पाइरा जानवरों और मनुष्यों में संक्रामक बीमारी का कारण बनती है, जिसे लेप्टोस्पायरोसिस कहा जाता है। यह दुनिया का सबसे आम ज़ूनोसिस माना जाता है और यह खराब स्वच्छता सेटिंग्स, कृषि व्यवसायों और हाल ही में मिट्टी, ताजे पानी या मिट्टी से जुड़े साहसिक खेलों के साथ कृंतक से जुड़ा हुआ है।

इलाज

हल्के लेप्टोस्पायरोसिस के इलाज के लिए एंटीबायोटिक थेरेपी आम तौर पर आवश्यक नहीं होती है क्योंकि यह आमतौर पर स्वयं को सीमित करता है और अधिकांश मामलों में चिकित्सकीय ध्यान देने के बिना हल करता है। मौखिक रूप से लिया एंटीबायोटिक्स बीमारी की अवधि को कम करता है और सबसे महत्वपूर्ण रूप से मूत्र के माध्यम से लेप्टोस्पिरर्स के विसर्जन को कम करता है और कम करता है। प्रोफेलेक्टिक्स का उपयोग महामारी सेटिंग के लिए किया जा सकता है। यदि उपयोग किया जाता है, एंटीबायोटिक्स की आवश्यकता हो सकती है और उपचार में शामिल हो सकते हैं:

  • डॉक्सीसाइक्लिन
  • एमोक्सिसिलिन या एम्पीसिलीन
  • क्लैरिथ्रोमाइसिन या एजीथ्रोमाइसिन
  • फ्लुओरोक़ुइनोलोनेस जैसे लेवोफ्लोक्सासिन या सिप्रोफ्लोक्सासिन

गंभीर लेप्टोस्पायरोसिस वाले मरीजों को हेपेटिक, गुर्दे, सीएनएस और हेमेटोलॉजिकल जटिलताओं और सहायक चिकित्सा के लिए सावधानीपूर्वक प्रबंधन की आवश्यकता हो सकती है। गुर्दे की विफलता के मामले में पेरिटोनियल डायलिसिस या हेमोडायलिसिस की शुरुआती शुरुआत मृत्यु दर लगभग दो तिहाई कम हो सकती है। इनोट्रॉपिक एजेंट, नेत्रहीन बूंद या मूत्रवर्धक सभी अतिरिक्त सहायक देखभाल में शामिल हैं। यह बीमारी दुनिया भर में फैली हुई है लेकिन उष्णकटिबंधीय क्षेत्रों में सबसे आम है। लेप्टोस्पायरोसिस का प्रसार बदलते जलवायु पैटर्न और उससे संबंधित रुझानों के साथ बढ़ गया है। पक्षियों, सरीसृप, उभयचर और स्तनधारियों की एक विस्तृत श्रृंखला लेप्टोस्पाइरा से संक्रमित हो जाती है। मनुष्यों के लिए लेप्टोस्पाइरा के लिए पुरानी वाहक होने के लिए दुर्लभ है और इसलिए इसे आकस्मिक मेजबान माना जाता है।एक संक्रमित पशु के शरीर में श्लेष्म झिल्ली एक्सपोजर और त्वचा घर्षण लेप्टोस्पाइरा के लिए मुख्य ट्रांसमिशन गेटवे हैं। लेप्टोस्पायरोसिस उपचार जल्दबाजी के बिना शुरू करना चाहिए। संगत लक्षण वाले मरीजों में उपचार शुरू होता है। सीरोलॉजिकल पहचानने वाले लेप्टोस्पिरर्स के लिए मानक केवल संदर्भ प्रयोगशालाओं द्वारा किया जाता है। कांवालेस्सेंट सीरम और जोड़ा तीव्र नमूने निदान में देरी पुष्टि दे सकता है। मौखिक डॉक्सीसाइक्लिन बुखार की अवधि में कमी और सरल संक्रमण में प्रमुख लक्षणों को दिखाता है जिन्हें अस्पताल में भर्ती करने की आवश्यकता नहीं है। लेप्टोस्पिरोसिस के लिए अस्पताल में भर्ती होने वाले मरीजों को पेनिसिलिन जी खुराक के साथ सबसे अच्छा जवाब मिलता है। हेमेटोलॉजिकल, गुर्दे, हेपेटिक और सीएनएस (केंद्रीय तंत्रिका तंत्र) की भागीदारी के पर्यवेक्षित प्रबंधन के साथ सहायक थेरेपी, गंभीर लेप्टोस्पायरोसिस फॉर्म (वेइल बीमारी) से प्रभावित लोगों के लिए आवश्यक है।

लक्षण

  • ठंड के साथ अचानक बुखार।
  • गंभीर मांसपेशी दर्द के साथ तीव्र सिरदर्द)।
  • पेट में दर्द।
लोकप्रिय प्रश्न और उत्तर

Mam torch test krwaya jata hai or pregnancy ke during aciver dt 200 or macromycin tablets ka use kyu or kisliye kiya jata h.iska dose kitne dino ka hota hai during pregnency or over dose hone pr bache koi nuksan to nhi hota h na.

MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP)
Gynaecologist, Mumbai
aciver dt 200 is fiven to those who have certain infection. This medicine is not recommended for use in pregnant women unless necessary. Macromycin Tablet is an antibiotic used to treat a parasitic infection known as Toxoplasmosis. considered safe...

My questions are described as below. 1. If one having chronic psychological stress "while" receiving primary series of anti rabies vaccination which is 5 arv doses on post exposure prophylaxis, will high level of cortisol hormone or this chronic psychological stress during those times prevent our immune system to mount a proper response to the vaccine? 2. I believe reduction of antibodies level overtime is a normal process. Chronic psychological stress will be elevated cortisol hormone, does this high level of cortisol or chronic psychological stress causes formerly protected level 0.5iu of rabies antibodies drop to unproductive level? (hope to understand more about antibodies during this event as I ever administered 5 doses of arv 3 years ago) 2. If one having protective rabies antibodies level 0.50iu or more, our antibodies kill the virus instantly once it's in site before it enters the nerve? How long does it take for our antibodies to kill the virus? Assume the virus already entered the nerve and spinal cord but it hasn't reached the brain will our antibodies still be able to kill it? 3. Will chronic psychological stress or high cortisol level affect or alter hepatitis c antibodies and hiv antibodies "seroconversion" process? (means production of antibodies affected therefore unable to properly seroconvert of antibodies due to severe level of stress or chronic psychological stress) 4. For hiv infection I have seen few discussions from Dr. h. Hunter handsfield (hiv expert) through medhelp forum with his patients that antibodies will clear p24 out of the blood until p24 no longer detectable and excess antibodies will start detectable through serology blood test afterward as part of seroconversion. A. For hiv if one having psychological stress or chronic psychological stress or high cortisol level will production level of antibodies that produce by our immune system stop or delay while in the middle of clearing p24 due to stress? I seen some of this p24 discussion from h. Hunter handsfield m.d (hiv expert) with his patient which I screenshot their conversation in the attachment above (kindly refer to the attachment in the above for more detail) he mentioned "in other words, the p24 cannot become negative until at least several days (typically a couple of weeks) after antibody appears" by h. Hunter handsfield m.d. B. I'm concern about will antibodies stop or delay production during that stressful event due to stress which causes improper seroconversion? (probably similar questions to no. 3 but a little more detail:) 5. If one having chronic psychological stress and high cortisol level, will one seropositive infections such as hiv or hcv (hepatitis c) "seroreversion" to seronegative? (i do understand for hiv positive patient seroreversion for hcv is common, although i'm not hiv positive and read some cases mentioned antibodies for hcv persist for life, some said persist for many years or up to decades. 6. If one having psychological stress such as anxiety which is either chronic or not chronic does it affects seroconversion process of antibodies for treponemal test on infection like syphilis (such as tpha, fta-abs) or non treponemal test on syphilis? (such as vdrl, rpr). 7. If one having severe psychological stress anxiety or chronic psychological stress does it causes syphilis treponemal test or non treponemal test antibodies seroreversion? (despite I seen some expert discussed overtime seroreversion for non treponemal test which test turning to negative overtime is normal and is the only issue for non treponemal that might be due to the nature of the test itself which does not happen to treponemal test).

PhD - Psychology
Psychologist, Patna
If you have psychological stress you need psychological counseling services through the online or offline process for the positive attitude that will be better for recovery of your problem thank you.

I am 31 years old male, I have never taken any vaccines including polio since birth. Is there any option to take vaccines now and what are the vaccines I can take? Please guide.

C.S.C, D.C.H, M.B.B.S
Cardiologist, Alappuzha
There is no need for any polio now and you can take PCV vaccine against pneumonia duiue to P carinii bacteria and you can also take Typhoid vaccine and meningitis vaccines
1 person found this helpful

If I have been vaccinated at childhood for chicken pox, hepatitis a, hepatitis b, typhoid, etc then do I need to take all those vaccines again?

C.S.C, D.C.H, M.B.B.S
Cardiologist, Alappuzha
There is a need to take the vaccines if there were taken in your childhood. Only the chicken ox can give lifelong protection and hepatitis b also for a long time like 20 years or more
1 person found this helpful

Hi, Can eating food licked by a stray cat (status: unknown, cannot be monitored) cause rabies? This is my primary question. My other question is, what can be transmitted by eating food (probably) licked by a cat?

C.S.C, D.C.H, M.B.B.S
Cardiologist, Alappuzha
Rabies cannot spread by eating food licked by a stray cat (status: unknown, cannot be monitored). The animal need to bite and the saliva need to enter the body to get infected
1 person found this helpful
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