Cytokeratin 18 (CK 18) is a simple non invasive test that accurately distinguishes (NASH) nonalchoholic steatohepatitis from (NAFLD) non alcoholic fatty liver disease. Cytokeratins are proteins of intermediate filaments that contain keratin found in the intracytoplasmic cytoskeleton of epithelial tissue. Liver biopsy being the best standard for diagnosing NASH has its share of limitations. Therefore it is urgent and important to conduct a non invasive test that can accurately distinguish NASH from simple steatosis. NAFLD has become a very common but important problem due to its prevalence and progression to severe liver disease. It refers to excessive amount of lipid in the liver. In some individuals it progresses to NASH.
There is no particular drill that you need to follow for this test. An expert pathologist extracts a minimal amount of blood from a clearly visible vein from your arm. Therefore it is advisable to wear clothes accordingly i.e. a short sleeve dress or shirt or a t-shirt is recommended. There are no restrictions on having food before this test. However, some other tests might require fasting may be for 2 or more hours wherein you will be advised earlier. It is best to follow the instructions given to you by the lab assistant.
It helps to give a better understanding of a patient’s condition related to liver damage and the severity of the disease. CK 28 is basically a biomarker to detect developing fibrosis. A few symptoms are: Inflammation of the liver Cell ballooning and fibrosis Diagnosed liver cirrhosis Significant decrease in hemoglobin Helps the doctor decide whether or not the patient requires a liver transplant or can be cured with medicines or other medical interventions.
The expert will make you sit comfortably first so that you should not shake off suddenly due to the prick. A tight band will be tied at the upper arm to restrict the blood flow and direct it towards the lower arm. The expert will then examine the area behind your elbow to find the visible and prominent veins. A cotton swab dipped in spirit is used to clean the area to draw the blood from. Finally a needle is inserted through the vein and a syringeful of blood is drawn out and stored in a test tube with your name labeled on it. This sample of blood is then sent to the laboratory for investigation.
Type | Gender | Age-Group | Value |
---|---|---|---|
Amylase
|
Unisex
|
All age groups
|
40 - 140U/L
|
Ghee has lost its glory. In-spite of being a saturated fat, ghee has shown to reduce both serum and intestinal cholesterol by triggering secretion of billiard lipids.
Reasons to consume ghee in your diet:
1. Ghee is also called as clarified butter. It’s short chain fatty acid structure imparts lipolysis properties which helps in breaking down the fat itself.
2. It’s antibacterial and antiviral properties makes it a perfect immune booster.
Vitamin D and pregnancy hand in hand go together. Expecting mothers need ensure they get the recommended amounts of Vitamin D during pregnancy for the healthy development of the baby as well as their own well-being.
Vitamin D is a fat-soluble vitamin obtained mostly from consuming fortified milk or juice, fish oils, and dietary supplements. It also is produced in the skin by exposure to sunlight. Vitamin D which is ingested or produced in the skin must undergo hydroxylation in the liver and kidney to promote absorption of calcium from the gut to enable normal bone mineralization and growth. Severe maternal Vitamin D deficiency has been associated with congenital rickets and disordered skeletal homeostasis coupled with fractures in the new-born during pregnancy. Vitamin D is necessary for the metabolism and absorption of phosphorus and calcium. Many studies are finding a connection between low serum vitamin D levels and an increased risk of certain types of autoimmune disease, cancers, insulin resistance, neurological disease and cardiovascular disease.
Latest studies have shown that Vitamin D deficiency is common during pregnancy especially among women residing in northern latitudes, living in cold climates or wear sun and winter protective clothing and ethnic minorities, especially those with darker skin. As the Vitamin D level of new-born is largely dependent on maternal Vitamin D status, the infants of mothers with vitamin D deficiency are also at risk of Vitamin D deficiency. Inadequate vitamin D can lead to abnormal bone growth, fractures, or rickets in new-borns. Deficiency of vitamin D leads to a higher risk of pregnancy complications like gestational diabetes, premature birth and low birth weight.
The symptoms of a vitamin D deficiency include aching muscles, bone pain, and softened bones leading to fractures. Fish liver oil, fatty fish, and eggs are excellent food source for Vitamin D. It is difficult to get sufficient vitamin D from food, which makes it necessary to have Vitamin D supplements. Since the skin uses the sun's rays to produce vitamin D, limited sun exposure is recommended. Exposure to the sun's ultraviolet rays intensifies the pigment changes causing skin darkening in pregnant women. Thus, most doctors endorse that pregnant women protect themselves from the sun and get their vitamin D from supplements. The average prenatal vitamin contains 400 IU of vitamin D, which makes it imperative that additional supplements should be taken. The significant compounds for human development are D2 and D3. The best way to really ensure adequate vitamin D is through simple supplementation. Ergocalciferol is the vegetarian form of vitamin D whereas cholecalciferol is the animal-sourced form, derived from fish liver oil or lanolin from sheep.
Luscious, healthy hair is undoubtedly one of the most prominent feature that adds charm to your personality. However, a minor or severe form of physical or mental stress and related problems can adversely affect your hair health and growth pattern.
Are you losing too many hair strands in a day?
If yes, then tentatively, how many?
If the number is about 100, then you need not worry, however, if it is beyond 100 you need to get cautious.
On an average, an adult has 100,000 to 150,000 hair and each hair follicle has its own life cycle, and traverses through three phases during its growth phase; anagen (active hair growth takes place), catagen (transitional hair growth), and telogen (resting phase after which the hair sheds off). Hair fall is a normal physiological process in which the hair completes its life cycle and sheds off. However, excessive hair fall is a health concern that needs thorough evaluation and treatment.
Have you heard of telogen effluvium?
Telogen effluvium (TE) also called as hair loss is a common dermatological condition which causes increased shedding of hair. This happens when there is a premature arrest of the growth of hair follicles and these follicles enter into the telogen phase (resting) followed by diffuse thinning of hair on the scalp. In most cases, the hair thins on the top of the scalp compared to the sides and back of the scalp. The hair loss is temporary and the hair soon recovers.
How common is telogen effluvium in India?
Studies suggest that TE is amongst the most common cause of hair loss. It can occur in both males and females. However, it is found to be more common in females.
What are the common causes of telogen effluvium?
Common causes of TE include certain medical condition, stress, pregnancy, crash dieting, nutritional deficiencies, intake of certain medicines, and physical trauma.
A common cause of hair loss in the Indian population is diet. A major proportion of the Indian population consumes a diet lacking essential amino acids, vitamins, and minerals, predisposing the population to this condition. It, therefore, becomes more important to include vital minerals such as zinc, amino acids (such as L-lysine), and vitamins (such as B6 and B12) to your daily diet or to take supplements available in the market.
Are Indians at an increased risk of nutritional deficiencies?
Yes, Indians are at an increased risk of nutritional deficiencies. Several research studies conducted in the past outline a direct association of nutritional deficiencies with hair loss.
In fact, according to a clinical survey published in Indian Medical Gazette, 9 out of 10 people in the country are unable to consume adequate amount of proteins. Working population settled in urban areas have been found to be most commonly affected by protein deficiencies.
How can you ensure healthy and luscious hair?
Simple 7 steps to healthy hair
Volumes of literature support the need for adding nutritional supplements to the diet to avert the occurrence of hair fall. Often TE gets better once the trigger for the condition is taken care of. However, if in case it persists make sure you consult a medical professional at the earliest.
Step 1: It’s all about what you eat (have a BALANCED DIET!!!)
Step 2: Massage your scalp regularly
Massage has been found to improve the blood circulation to the hair follicles and stimulates hair growth. Try essential oils such as olive oil, castor oil, rosemary oil, and coconut oil to massage your scalp. Warm oil helps penetrate the scalp more effectively. You can also apply hair serums that are enriched with nutrients that nourish the hair and keep it healthy.
Step 3: Choose your SHAMPOO wisely
Watch out for harsh chemicals like parabens, lauryl sulfate, and sodium chloride. Parabens which are used as preservatives in shampoos can mimic as estrogens which lead to hair loss. Lauryl sulfate, an anionic surfactant used in many cleaning and hygiene products, also cause hair fall. You can also apply certain over-the-counter products that help in better penetration of anti-hair fall medications and enhance their action.
Step 4: Get sufficient Vitamin D (Don’t hide from the sun)
Little do we realize that sunlight actually plays a critical role in promoting hair growth. Sunlight helps you get your daily dose of Vitamin D which is helpful in managing hair fall, so don’t hide from it!
Step 5: Say NO to stress
Stress is amongst the key factors governing a happier and healthier you. So, make sure it does not serve as a roadblock in your health.
Eat healthy and bring in basic lifestyle changes in your day to day life to avert the chances of triggered hair fall.
Step 6: Go for hair growth supplements
-Keratin makes up most of our hair strands and amino acids such as cysteine, lysine, arginine, and methionine play a critical role in the formation of the hair strands. The market is loaded with several supplements (oral and topical) that help to provide the hair with essential nutrients and vitamins. You can choose to pick supplements that are a source of vital minerals and vitamins essential for hair growth.
Step 7: Seek help from a dermatologist/ trichologist
Skin care tips
Hair care tips
Hair fall or loss is a multifactorial problem where hereditary along with environmental factors and diet play an important role. Iron deficiency along with essential things like biotin, vitamin a along with other nutrients have a major role to play. Lotions, serums, tablets along with specified shampoos and conditioners can also help. Mesotherapy and prp are promising therapies which can be tried. All these treatment definitely need maintenance sessions along with local lotions application under the supervision of dermatologist. All the best and take care. Patients need multiple sessions for better outcome along with medical analysis. Hope this is of some help to you. One can take biotin tablets along with vitamin a rich diet and lots of red grapes with seeds.