Apo B/Apo A1 Ratio Test

Apolipoprotein is the protein associated with the largest component for High-Density Lipoprotein (HDL). The Apolipoprotein A1 represents about 45% molecular mass approximately. It aids in the reverse processing of the cholesterol from tissue to the liver. The test evaluates the survival rate or risk involved in heart patients and peripheral vascular diseases. Apo plays the most important role in the lipoprotein metabolism like transportation of hydrophobic molecules that are present in the plasma aqueous medium, cell surface and binding specific receptors correctly direct lipids along with targeting the organs as well as body tissues. acts as co-factor to the enzyme lecithin-cholesterol acyltransferase along with the cholesterol from cells.

Logistic regression will be used for estimation of the process between apoB/apoA1 ratio as well as the risk of MetS. Receiver Operating Characteristics (ROC) curve analysis will be performed according to the test and enables the predictive value of apoB/apoA1 ratio. Blood serum sample is required for obtaining the Apolipoprotein measurements. Some medicines, herbal supplements, vitamins, and nutritional supplements affect the test adversely, so let the doctor know the same. No need for any particular Preparation for the Apolipoprotein A1 ratio tests is required. If you feel any uneasiness then it is necessary to report accordingly. You need to fast for 12-14 hours preceding the test, however, keep yourself hydrated.

The test is sometimes used as a substitute for the total cholesterol test. Apolipoprotein measurements are methodological benefits when compared to the LDLc quantification. LDL is quantified have Friedewald equation16 that offers the estimation of LDL values, which is also quite easier for determining the total cholesterol, HDL levels17 and triglyceride. The approximation also includes the possible analytical errors based on 3 parameters to calculate the LDLc and also increases likelihood errors enabling potential impact. Apolipoproteins ratio could measure directly

• Hyperthyroidism
• Malnutrition
• Reye syndrome
• Weight reduction
• Severe illness
• Surgery
• Cirrhosis
• Diabetes.

Apolipoproteins A1 (apo A-1) test measures amount of apo A-1 in the blood. The vein in elbow pit is pierced with a sterilized needle and A blood sample is drawn. The serum is separated from it for testing. Apolipoproteins are combined with the lipids for transporting in the bloodstream. Apolipoprotein A1 test is done with Apolipoprotein B and the ratio is recorded in the report. This helps in assessing the risk of cardiovascular disease.