The ASKA Striated Muscle Antibody Test is used as the diagnosis of Myasthenia Gravis. Myasthenia Gravis, an autoimmune neurological disease, is characterized by muscle fatigue and inactivity, primarily in voluntary muscles. The Lab Test is to assess levels of abnormal antibodies in the serum of the patient. These abnormal antibodies are responsible for blocking receptor sites of Acetylcholine, a major neurological transmitter. The test is normally advised for patients with chronic fatigue, droopy eyelids, delayed muscle response and slow chewing.
No special preparations are required for this test. Since it is a blood test, a shirt with short sleeves should be worn by the patient. The doctor should be informed of any medications the patient is prescribed or any allergies he suffers from. There is no restriction to the diet of the patient, however, any instructions from the lab must be followed.
To test antibody levels, the serum of the blood sample is analysed. The results are interpreted as follows: Positive test for presence of autoimmune antibodies: Thymoma Possibility of Myasthenia Gravis Small cell lung cancer Negative test for presence of autoimmune antibodies: Does not rule out possibility of Myasthenia Gravis, but directs towards other diagnostic tests.
A small sample of blood will be drawn from the patient's arm, and the serum will layer be tested. The procedure for obtaining the blood sample is: The site will be cleaned with an alcohol swab. A sterile needle will be inserted into the arm of the patient. A blood sample of 2ml will be drawn from the patient's arm. The site will be cleaned with a cotton swab. If required, the site will be bandaged.