KIT2 Exons Test

This test detects KIT gene mutation in exons 8 to 11 and 17. These mutations occur in hematologic malignant neoplasms (Myeloid leukemia and mastocytosis). It identifies mutations in these tumors. This KIT mutation leads to cell proliferation and reduced apoptosis. It uses sequencing of the exons to recognize the above mutations. The mutation in the KIT gene may thus lead to acute myeloid leukemia ( cancer in blood and bone marrow with excess number of immature WBCs) and mastocytosis (mast cells accumulate in skin or internal organs)

No specific preparation is required for the test. But consult the doctor if the doctor requires running some other tests too.

The test detects mutation in KIT gene The test assesses the presence of acute myeloid leukemia. It also helps to diagnose mastocytosis.

A standard DNA test requires only a blood or saliva sample. Mostly, blood will be used for the DNA extraction. The blood will be drawn after the surface of the skin is cleaned with alcohol. Blood will be drawn from a brand new syringe and a cotton will be given soon after to help it clot. The sample is taken to the lab for testing.