Sjogren's Antibody (SS-A)/(Anti-RO) Test

Generally long term diseases are subjected to various other disturbances over the body and Sjogren Syndrome is one such disease. Basically Sjogren Syndrome is an autoimmune disease where a person’s moisture producing glands are affected. The primary effects include dry mouth and dry eyes and these are followed by other symptoms like dry skin, vaginal dryness, chronic cough, muscle and joint pains and thyroid problems. In other words, this syndrome causes dryness both internally and externally to a person’s body. This syndrome is generally occurred in combination of genetic and environmental disparities like abnormal exposure to virus and bacteria. The later stages of the body exposure to virus and bacteria lead to connective tissue disorders and this inflammation results in an uncertain damage to glands.

Patient should be informed about types of tests that needs to be done and also the procedures about each test. Equipment related to the type of test being performed should be cleaned and made stained before using it on the patient. If the Physician’s request for a Blood test, then a narrow needle and test tubes should be prepared, when the test to be done is Eye then the a curved glass container should be picked that is cleaned in prior.

The anti-Ro/SSA clinical test portraits the significance of U1 ribonucleoprotein and Ribosomal P Protein that are reviewed in the test for the patient. Also the patient can be separated from double stranded DNA antibodies. The Ro/SSA has two subsets, Ro60 that is localized to the cell nucleus and the role of Ro60 is to regulate messenger RNA stability and translation. This R60 also contains glomerulonephritis, which has an important role in preventing systemic autoimmune diseases. The R052 is localized to the cell cytoplasm that is basically an interferon-inducible protein which is derived from “tripartite motif” family of proteins. This protein basically acts as E3 Ubiquitin ligase.

Generally for the blood test which is very similar to a normal blood test, 5-10 ml of blood sample needs to extracted and sent to the examination procedures. For the eyes test, the tears are collected in a glass container that are tested using some catalysts. For the Dental test, the spit/saliva is collected in a glass contained which is further processed to continue to other tests. Then the samples are shipped to normal temperature zone where the actual examination is done.