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Overview

Avomine 25Mg Tablet

Manufacturer :  Abbott India Ltd
Medicine Composition :  Promethazine
Prescription vs OTC : Prescription by Doctor not required

About Avomine 25Mg Tablet

Avomine 25Mg Tablet is prescribed for symptomatic treatment of various allergic conditions. It is also used as an antiemetic, to treat motion sickness, as a sedative. This medicine also employes as an analgesic adjunct for control of postoperative pain or an anesthetic adjunct.

Belonging to a group of drugs called phenothiazines, Avomine 25Mg Tablet is used to treat allergies with symptoms like a runny nose, hives, and watery eyes. Acting as an anti-histamine, it blocks the effect of histamine in the body. It is also helpful in treating motion sickness, nausea, and vomiting. It is often utilized as a sleeping aid.

If you are allergic to similar medicines like chlorpromazine, mesoridazine, fluphenazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine, Avomine 25Mg Tablet is not to be used. If you suffer from medical conditions such as seizures, glaucoma, liver and heart disease, sulfite allergy, or an enlarged prostate, alert your doctor. The drug is not for children under the age of 2.

Follow all the instructions given by your doctor while taking Avomine 25Mg Tablet. It is taken before meals or at bedtime. The medicine must be measured properly using proper dosage spoons. If it is to be used for surgery, it is usually taken the night before the procedure.

Caution in breast cancer or other prolactin-dependent tumors (may elevate prolactin levels). It may alter temperature regulation or mask toxicity of other drugs due to antiemetic effects. May alter cardiac conduction - life threatening arrhythmias have occurred with therapeutic doses of phenothiazines.

This medicine may cause orthostatic hypotension; use with caution in patients at risk of hypotension or where transient hypotensive episodes would be poorly tolerated (cardiovascular disease or cerebrovascular disease).

    What are the uses of Avomine 25Mg Tablet

    What are the contraindications of Avomine 25Mg Tablet ?

    What are the side effects of Avomine 25Mg Tablet ?

    Key highlights of Avomine 25Mg Tablet

    • Is It safe with alcohol?

      Alcohol consumption along with this medicine is not recommended as it enhances the risk of side effects like dizziness and difficulty in concentration.

    • Are there any pregnancy warnings?

      This medicine should be avoided by pregnant women unless suggested by the doctor.

    • Are there any breast-feeding warnings?

      This medicine should be avoided by breastfeeding women unless suggested by the doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      Caution to be advised in patients with an impaired renal function.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • How long is the duration of effect?

      The duration for which this medicine will remain active is about 2 - 6 hours.

    • What is the onset of action?

      The effect of this medicine is initiated within 20 minutes after its administration.

    What are the substitutes for Avomine 25Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Avomine 25Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of this tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    • Are there any overdose instructions?

      In case of overdose, consult your doctor.

    How does this medication work?

    This tablet counteracts with independent histamine for binding at H1-receptor sites in places like the GI tract, uterus, bronchial muscle, and, large blood vessels. It causes symptoms of nausea to subside via anticholinergic actions and by implicating activity on the medullary chemoreceptor trigger region.

      What are the interactions of Avomine 25Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction of this medicine with alcohol may cause CNS depression and psycho-motor impairment.
      • Interaction with Lab Test

        Alters the flare response in intradermal allergen tests
      • Interaction with Medicine

        Concomitant use of this medicine must be avoided along with the below mentioned medicines:
        • CYP2D6 enzyme substrate.
        • Benztropine (and other anticholinergics) may inhibit the therapeutic response to Avomine 25Mg Tablet and excess anticholinergic effects may occur.
        • Chloroquine may increase Avomine 25Mg Tablet concentrations.
        • Cigarette smoking may enhance the hepatic metabolism of Avomine 25Mg Tablet. Larger doses may be required compared to a nonsmoker.
        • Concurrent use of Avomine 25Mg Tablet with an antihypertensive may produce additive hypotensive effects.
        • Antihypertensive effects of guanethidine and guanadrel may be inhibited by Avomine 25Mg Tablet.
        • Concurrent use with TCA may produce increased toxicity or altered therapeutic response.
        • Avomine 25Mg Tablet may inhibit the antiparkinsonian effect of levodopa; avoid this combination.
        • Avomine 25Mg Tablet plus lithium may rarely produce neurotoxicity.
        • Barbiturates may reduce Avomine 25Mg Tablet concentrations.
        • Propranolol may increase Avomine 25Mg Tablet concentrations.
        • Sulfadoxine-pyrimethamine may increase Avomine 25Mg Tablet concentrations.
        • Avomine 25Mg Tablet and possibly other low potency antipsychotics may reverse the pressor effects of epinephrine.
        • Avomine 25Mg Tablet and CNS depressants (ethanol, narcotics) may produce additive CNS depressant effects.
        • Avomine 25Mg Tablet and trazodone may produce additive hypotensive effects.
      • Interaction with Disease

        May impair physical or mental abilities; patients must be cautioned about performing tasks which require mental alertness (ie, operating machinery or driving). Effects with other sedative drugs or ethanol may be potentiated. Avoid use in Reye's syndrome. Use with caution in Parkinson's disease; hemodynamic instability; bone marrow suppression; predisposition to seizures; subcortical brain damage; and in severe cardiac, hepatic, renal, or respiratory disease.

      FAQs about Avomine 25Mg Tablet

      • Ques : What is avomine 25mg tablet?

        Ans : This medicine belongs to the class of drugs knowns as Antihistamine, which is prescribed to the patients having Nausea and vomiting.

      • Ques : What are the uses of avomine 25mg tablet?

        Ans : This tablet is used for the treatment and prevention from conditions and symptoms like Urticaria, Rhinitis, Preoperative sedation.

      • Ques : What are the Side Effects of avomine 25mg tablet?

        Ans : The side effects include Drowsiness, Seizures, Tremors, and headache. Apart from these, the tablet may further lead to Excitation, Strength losing, skin rashes, and Sunlight sensitivity.

      • Ques : What are the instructions for storage and disposal avomine 25mg tablet?

        Ans : This tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and animals.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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