Azithral 500 MG Tablet

Azithral 500 MG Tablet is an antibiotic used to treat different types of infections in the throat, lungs, skin and ears caused by a variety of bacteria. It belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections and traveler’s diarrhea.

It is prescribed for the treatment of mild to moderate upper and lower respiratory tract infections, infections of the skin, and skin structure. The medication also helps against number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia

You should not consume the tablet without consulting a doctor if you have:

• Allergy
• Jaundice
• Liver problems
• Myasthenia gravis
• Heart rhythm disorder
• History of long QT syndrome.

Few common side effects of this tablet include nausea, vomiting, stomach upset and diarrhoea. An allergic reaction can also occur in rare cases. The dosage will depend on your age, the severity of your condition, your medical history, and how you react to the first dose.

It is also used for preventing or delaying the onset of infection with Mycobacterium avium complex (MAC). Also, prescribed for prophylaxis of bacterial endocarditis in patients who are allergic to penicillin and undergoing surgical or dental procedures.

Along with other medications, it is sometimes used for curing malaria. This drug is also used to treat several intestinal infections and sexually transmitted infections. This medicine is not recommended for use in case of a common cold, flu, or viral infection since it is active against infections caused by bacteria only.

Symptoms of overdose include nausea, vomiting, diarrhea, and prostration. Treatment is supportive and symptomatic. Take as directed. Take all of the prescribed medication. Do not discontinue until prescription is completed.

Take suspension 1 hour before or 2 hours after meals; tablet form may be taken with meals to decrease GI effects. Do not take with aluminum- or magnesium-containing antacids. May cause transient abdominal distress, diarrhea, and headache.

Report signs of additional infections (eg, sores in the mouth or vagina, vaginal discharge, unresolved fever, severe vomiting, or diarrhea). Safety and efficacy of Azithromycin have not been established in children <6 months of age with acute otitis media and in children <2 years of age with pharyngitis/tonsillitis.

• Community Acquired Pneumonia

• Ear Infection (Otitis Media)

• Pharyngitis/Tonsillitis

• Skin And Soft Tissue Infections

• Liver Damage

• Hypersensitivity

• Diarrhoea

• Dry Or Scaly Skin

• Abdominal Pain

• Difficulty In Swallowing

• Vomiting

• Fever

• Acid Or Sour Stomach

• Aggression Or Anger

• Excessive Air Or Gas In Stomach

• Heartburn

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 2 to 4 days.

• What is the onset of action?

  The effect of this medicine can be observed within 2 to 3 hours of dose administration.

• Are there any pregnancy warnings?

  Use of this medicine is not recommended in pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  As low levels of this medicine is excreted through human breast milk monitoring of possible side effects in the infant like Diarrhoea, Candidiasis is necessary.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Consult a doctor before taking the medicine when consuming alcohol.

• Is it safe to drive while on this medicine?

  The side effects of this drug can be adverse and when facing the same, driving should be completely avoided.

• Does this affect liver function?

  It should be avoided if the person is suffering from any type of liver disease.

• Does this affect kidney function?

  Caution must be taken while taking this medication in patients with kidney disease. Adjustment of dose is required, thus consult your doctor before taking Azithral 500 MG Tablet.

Below is the list of medicines, which have the same composition, strength and form as Azithral 500 MG Tablet , and hence can be used as its substitute.

• Unizith 500 MG Tablet

  Sanofi India Ltd

• Azifine Plus 500 MG Tablet

  Glenmark Pharmaceuticals Ltd

• Azlupin 500 MG Tablet

  Lupin Ltd

• Topmac 500 MG Tablet

  Tablets India Ltd

• Corzi 500 MG Tablet

  Dwd Pharmaceuticals Ltd

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical attention or contact your doctor in case of over dose.

This medicine is a bacteriostatic drug. It inhibits protein synthesis by binding itself to 50S ribosomal subunits of the sensitive micro-organism.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Monitoring should be done of liver function tests and CBC differential when the patient is on this medicine.

• Interaction with Medicine

  • May inhibit CYP3A3/4 enzyme (mild).
  • Increased effect/toxicity: Azithral 500 MG Tablet may increase levels of tacrolimus, phenytoin, ergot alkaloids, alfentanil, astemizole, terfenadine, bromocriptine, carbamazepine, cyclosporine, digoxin, disopyramide, and triazolam; Azithral 500 MG Tablet did not affect the response to warfarin or theophylline although caution is advised when administered together.
  • Avoid use with pimozide due to significant risk of cardiotoxicity.

• Interaction with Disease

  • Qt Prolongation: Inform your doctor if you have an arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs, anti-arrhythmic drugs.
  • Liver Disease: Inform your doctor if you have any liver disease and drugs that cause liver damage (Eg: TB drugs, HIV drugs).
  • Myasthenia Gravis: This medicine has certain interactions with diseases. A few of the diseases it interacts with are QT Prolongation, Liver disease and Myasthenia Gravis.
  • Use with caution in patients with hepatic dysfunction; hepatic impairment with or without jaundice has occurred chiefly in older children and adults.
  • It may be accompanied by malaise, nausea, vomiting, abdominal colic, and fever; discontinue use if these occur.
  • May mask or delay symptoms of incubating gonorrhea or syphilis, so appropriate culture and susceptibility tests should be performed prior to initiating Azithral 500 MG Tablet.
  • Pseudomembranous colitis has been reported with use of macrolide antibiotics.

• Interaction with Food

  Rate and extent of GI absorption decreased; take this medicine on an empty stomach.

• Ques : What is azithral 500 mg tablet?

  Ans : Azithral Tablet belongs to the antibiotic group of medicines. It is used in the treatment of infections caused by a variety of bacteria.

• Ques : What is azithral 500 mg tablet used for?

  Ans : Azithral 500 MG is used for the treatment and prevention from conditions and symptoms of diseases like community-acquired pneumonia, ear infection, pharyngitis or tonsillitis, skin, and soft tissue infections.

• Ques : What are the side effects of azithral 500 mg tablet?

  Ans : Diarrhea, abdominal pain, difficult or painful urination, fever, acidic stomach, vomiting, heartburn, dry or scaly skin, dizziness are some of the common side effects.

• Ques : Does Azithral 500 mg cause dizziness?

  Ans : Yes, Azithral can cause dizziness and drowsiness. The patients should consult a doctor if these side effects often occur.

• Ques : Are there any specific contraindications associated with the use of Azithral 500 mg tablet?

  Ans : Azithral 500 mg is contraindicated in patients having allergic reactions, diarrhea and hypersensitivity.

• Ques : what precautions should you take while using Azithral 500 mg tablet?

  Ans : Patients should not use Azithral tablet during pregnancy and while breastfeeding. Those who have allergies or any pre-existing diseases such as hypersensitivity and liver diseases should avoid taking this medication.

• Ques : Should I use azithral 500 mg tablet empty stomach, before food or after food?

  Ans : Azithral tablet is advised to take after meals to avoid gastric reflux and stomach disorders. It is advised to consult a doctor before using this medication.

• Ques : What are the instructions for storage and disposal of azithral 500 mg tablet?

  Ans : Azithral 500 mg should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Azithromycin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/azithromycin

• Azithromycin: Uses, Side Effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 24 April 2019]. Available from:

  https://www.drugsbanks.com/azithromycin/

• Azithromycin 500 mg Film-coated Tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 08 May 2019]. Available from:

  https://www.medicines.org.uk/emc/product/8426/smpc