Betacap 40 MG Capsule TR

Betacap 40 MG Capsule TR is used for the management of high blood pressure (hypertension), angina pectoris, pheochromocytoma, essential tremor, tetralogy of Fallot cyanotic spells, and arrhythmias (such as atrial fibrillation and flutter, A-V nodal re-entrant tachycardias, and catecholamine-induced arrhythmias).

It is also used in the prevention of myocardial infarction, migraine headache. Betacap 40 MG Capsule TR is also helpful in treating the prevention of myocardial infarction, migraine headache.

This medication is a beta-blocking agent that attaches itself to the heart and inhibits the regular molecules from triggering the receptors. It blocks the beta-adrenergic receptors in the heart, thus slowing your heartbeat down and lowering the blood pressure. This lowers the stress placed on your heart, arteries, veins and blood vessels, decreasing the workload of the heart.

The medicine might not be suitable for everyone as it can have harmful effects on people with certain conditions. Before beginning a course of this medication, you need to notify your doctor if you are-

• Pregnant or breastfeeding, or
• Suffering from conditions such as:
• Asthma,
• Diabetes mellitus,
• Psoriasis,
• Liver or kidney problems,
• Severe heart condition.

The medicine must be taken according to the doctor’s prescription. The doctor might recommend taking it two, three or even four times a day. You must complete the course of this medication otherwise it can cause you to develop withdrawal symptoms.

Symptoms of intoxication include cardiac disturbances, CNS toxicity, bronchospasm, hypoglycemia and hyperkalemia. The most common cardiac symptoms include hypotension and bradycardia; atrioventricular block, intraventricular conduction disturbances, cardiogenic shock, and asystole may occur with severe overdose, especially with membrane-depressant drugs (eg, propranolol); CNS effects include convulsions, coma, and respiratory arrest is commonly seen with propranolol and other membrane-depressant and lipid-soluble drugs.

Treatment includes symptomatic treatment of seizures, hypotension, hyperkalemia and hypoglycemia; bradycardia and hypotension resistant to atropine, isoproterenol or pacing may respond to glucagon; wide QRS defects caused by the membrane-depressant poisoning may respond to hypertonic sodium bicarbonate; repeat-dose charcoal, hemoperfusion, or hemodialysis may be helpful in removal of only those beta-blockers with a small Vd, long half-life or low intrinsic clearance (acebutolol, atenolol, nadolol, sotalol).

Take exactly as directed; do not increase, decrease, or discontinue without consulting prescriber. Take at the same time each day. Tablets may be crushed and taken with liquids. Do not alter dietary intake of protein or carbohydrates without consulting prescriber.

• Hypertension

• Angina Pectoris

• Migraine

• Anxiety

• Allergy

• Sinus Bradycardia

• Cardiogenic Shock

• Pregnancy

• Chest Pain

• Hypotension

• Cardiogenic Shock

• Light Headedness

• Confusion

• Dizziness

• Insomnia

• Fatigue

• Lethargy

• Cold Extremities

• Vertigo

• Syncope

• Hallucination

• Rash

• Alopecia

• Pruritus

• Urticaria

• Contact Dermatitis

• Diarrhoea

• Nausea

• Vomiting

• Stomach Discomfort

• Anorexia

• Impotence

• Thrombocytopenia

• Weakness

• Wheezing

• Bronchospasm

• Pharyngitis

• How long is the duration of effect?

  Betacap remains in your body 6-12 depending upon the body type metabolism. In some cases the duration of effect can be up to 24 hours depending upon the regular blood pressure cycle or haemoglobin content.

• What is the onset of action?

  Betacap sustains a quick onset, the fast effects of the medicine can be easily noticed after 2 hours of oral administration. The onset time can vary with the context of prescription with the different symptoms for which the medicine is generally prescribed.

• Are there any pregnancy warnings?

  The use of this medicine is not recommended for pregnant women as there is a lack of conclusive evidence from clinical studies.

• Is it habit forming?

  Mild to moderate habit forming tendencies have been reported and hence requires careful administration and withdrawal.

• Are there any breast-feeding warnings?

  Breastfeeding women must consult doctor before using this medication.

• Is It safe with alcohol?

  Consumption of alcohol along with Propranolol is found to be unsafe. Thus it should be avoided.

• Is it safe to drive while on this medicine?

  Use caution when driving, climbing stairs, or changing position - rising from sitting or lying to standing - or engaging in tasks requiring alertness until response to drug is known.

• Does this affect kidney function?

  This medicine is found to be safe to use in patient with kidney disease. Marked slowing of heart rate may occur in cirrhosis with conventional doses. Low initial dose and regular heart rate monitoring.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Dosing adjustment in renal impairment:

  • Clcr 31-40 mL/minute: Administer every 24-36 hours or administer 50% of normal dose.
  • Clcr 10-30 mL/minute: Administer every 24-48 hours or administer 50% of normal dose.
  • Clcr <10 mL/minute: Administer every 40-60 hours or administer 25% of normal dose.
  • Hemodialysis: Not dialyzable (0% to 5%); supplemental dose is not necessary.
  • Peritoneal dialysis: Supplemental dose is not necessary.
  Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Betacap 40 MG Capsule TR , and hence can be used as its substitute.

• Migrabeta 40 MG Capsule TR

  Alkem Laboratories Ltd

• Promotil Tr 40 MG Capsule TR

  Torrent Pharmaceuticals Ltd

• Are there any missed dose instructions?

  If one dose is missed and the next recommended dosage is no more than 4 hours away, you can skip the dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

The exact mechanism of action of this drug for all the indications is not established. However, this medicine non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Betacap 40 MG TR Capsule interaction is strictly prohibited with alcohol as the catalysing affect of the medicine can increase with usage of alcohol known to slow down cardio-vascular activities. You should consult your nearest doctor regarding substituting the dosage if usage of alcohol cannot be compromised on daily basis.

• Interaction with Lab Test

  This medicine might cause fluctuation in serum level of thyroxine [increased level of thyroxine (S)].

• Interaction with Medicine

  • Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
  • Antipyrine's clearance is reduced by 30% to 40%.
  • Cimetidine increases the plasma concentration of Betacap 40 MG Capsule TR and its pharmacodynamic effects may be increased.
  • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
  • Epinephrine (including local anesthetics with epinephrine): Betacap 40 MG Capsule TR may cause hypertension.
  • Flecainide: Pharmacological activity of both agents may be increased when used concurrently.
  • Fluoxetine may inhibit the metabolism of Betacap 40 MG Capsule TR, resulting in cardiac toxicity.
  • Glucagon: Betacap 40 MG Capsule TR may blunt hyperglycemic action.
  • Haloperidol: Hypotensive effects may be potentiated.
  • Hydralazine: The bioavailability propranolol (rapid release) and hydralazine may be enhanced with concurrent dosing.
  • Insulin: Betacap 40 MG Capsule TR inhibits recovery and may cause hypertension and bradycardia following insulin-induced hypoglycemia. Also masks the tachycardia that usually accompanies insulin-induced hypoglycemia.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use of both.

• Interaction with Food

  Avoid natural licorice (causes sodium and water retention and increases potassium loss); protein-rich foods may increase bioavailability; a change in diet from high carbohydrate/low protein to low carbohydrate/high protein may result in increased oral clearance.

• Interaction with Disease

  • Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of propranolol in CHF has not been demonstrated).
  • Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
  • Use caution in patient with PVD.
  • Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms.
  • Can mask signs of thyrotoxicosis.
  • Can cause fetal harm when administered in pregnancy.
  • Use cautiously in hepatic dysfunction (dosage adjustment required).
  • Use care with anesthetic agents which decrease myocardial function.

• Ques : What is Betacap 40 MG Capsule TR?

  Ans : Betacap belongs to the class of drugs known as Beta-Blocker. It is used to treat irregular heartbeats, high blood pressure, excessive migraines, chest pain from angina, anxiety and to prevent heart attacks.

• Ques : What is Betacap 40 MG Capsule TR used for?

  Ans : Betacap is used for the treatment and prevention from conditions and symptoms of diseases like Fast heartbeat, Hypertension, and Elevated blood pressure.

• Ques : What are the side effects of Betacap 40 MG Capsule TR?

  Ans : Side effects include weakness, dizziness, irregular heartbeat, etc.

• Ques : Can Betacap 40 MG Capsule TR be used for fast heart beat and migraine?

  Ans : Yes, Betacap can be used to treat fast heartbeat.

• Ques : Are there any specific contraindications associated with the use of Betacap 40 MG Capsule TR?

  Ans : Betacap is contraindicated to patients having allergies, heart failure, asthma, diabetes, thyrotoxicosis and high blood pressure.

• Ques : What precautions should I take while using Betacap 40 MG Capsule TR?

  Ans : Betacap should be used with some precautions. It is important to take care of these precautions to avoid worsening conditions. Patients should not use betacap during pregnancy or breastfeeding.

• Ques : Should I use Betacap 40 MG Capsule TR empty stomach, before food or after food?

  Ans : Betacap is advised to take after meals to avoid stomach disorders. It is advised to consult doctor before use.

• Ques : What are the instructions for storage and disposal of Betacap 40 MG Capsule TR?

  Ans : Betacap 40 mg capsule tr should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Propranolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/propranolol

• Propranolol 40 mg film-coated tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 25 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/2904/smpc

• PROPRANOLOL HYDROCHLORIDE- propranolol hydrochloride capsule, extended release- Daily Med [Internet]. dailymed.nlm.nih.gov. 2015 [Cited 25 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4edba76-29b8-41fb-bf0b-d4633abba003