Bosentan

Bosentan is used to cure high blood pressure in patients. Known to be an endothelin receptor antagonist, the drug blocks a certain type of substance present in the lungs in order to lower blood pressure.

This medication should be avoided if:

• You are allergic to it.
• You are suffering from severe liver problems.
• You are breastfeeding or pregnant women.

The drug should be taken exactly as per the instructions of the doctor. It is meant for oral consumption and it can either be taken with or without food. Continue to take the drug as long as your doctor has instructed you to.

If you suddenly discontinue the drug, it may result in more complications. Like all medicines, it also causes some side effects which includes neutropenia, leukopenia, angioedema, headache, blurred vision, nasal congestion, flushing, hypertension, etc.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Pulmonary Hypertension

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Hypersensitivity

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Headache

• Increased Liver Enzymes

• Edema (Swelling)

• Allergic Reaction

• Anemia

• Flushing

• Angioedema

• Blurred Vision

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any pregnancy warnings?

  There is no reliable data found. Therefore, it is advised to take medical help before using this medication.

• Are there any breast-feeding warnings?

  It is not known whether the medicine is excreted into breast milk or not. You must consult doctor before consumption.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery.

• Does this affect kidney function?

  There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

• Does this affect liver function?

  Please consult doctor before consuming the drug.

• What is the onset of action?

  The onset of action is attained between 3 to 5 hours.

• How long is the duration of effect?

  The duration of effect of this medication is 5.4 hours.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Bosentan as ingredient

• Bosenat 125Mg Tablet

  Natco Pharma Ltd

• Bosentas 125mg Tablet

  Cipla Ltd

• Bozetan 125Mg Tablet

  Lupin Ltd

• Bosenat 62.5Mg Tablet

  Natco Pharma Ltd

• Bosentas 62.5mg Tablet

  Cipla Ltd

• Lupibose 62.5Mg Tablet

  Lupin Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medication behaves as an endothelin receptor antagonist that works by inhibiting the action of endothelin 1 by binding to and deactivating endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Medicine

  This drug interacts with ciclosporin, glibenclamide, warfarin, etc.

• Ques : What is Bosentan?

  Ans : This medication is used to treat hypertension.

• Ques : How long do I need to use Bosentan before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication.

• Ques : At what frequency do I need to use Bosentan?

  Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use Bosentan empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of Bosentan?

  Ans : It should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Bosentan-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/bosentan

• Bosentan-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00559

• BOSENTAN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=BOSENTAN