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Overview

Crocin Advance 500Mg Tablet

Manufacturer :  Glaxo SmithKline Pharmaceuticals Ltd
Medicine Composition :  Paracetamol
Prescription vs OTC : Prescription by Doctor not required

About Crocin Advance 500Mg Tablet

Crocin Advance 500Mg Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

  • You are allergic to this medicine.
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

There are several drugs that may interact with Crocin Advance 500Mg Tablet. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products.

For adults Crocin Advance 500Mg Tablet the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Crocin Advance 500Mg Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Crocin Advance 500Mg Tablet.

There are several drugs that may interact with Crocin Advance 500Mg Tablet. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products. For adults Crocin Advance 500Mg Tablet the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Crocin Advance 500Mg Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Crocin Advance 500Mg Tablet.

    What are the uses of Crocin Advance 500Mg Tablet

    • Fever And Pain

    • Headache

    • Muscle Pain

    • Menstrual Cramps

    • Arthritis

    What are the contraindications of Crocin Advance 500Mg Tablet ?

    • Allergy

    • Impaired Kidney Function

    • Impaired Liver Function

    What are the side effects of Crocin Advance 500Mg Tablet ?

    Key highlights of Crocin Advance 500Mg Tablet

    • How long is the duration of effect?

      The effects of crocin advance can last you about four to six hours.

    • What is the onset of action?

      Crocin medication starts to work within an hour of administration when the intention of use is to relieve pain. For tackling with fever, the time taken by the medicine to act takes about thirty minutes.

    • Are there any pregnancy warnings?

      This medication should only be used by pregnant after consultation with their healthcare provider. Although crocin advance has not been known to cause any harm to the fetus, precautionary measures should be enforced at all times during the period of pregnancy.

    • Is it habit forming?

      Crocin advance has not been reported to show signs of habit developing tendencies.

    • Are there any breast-feeding warnings?

      Although this medication is relatively safe for use during breastfeeding, it is advised that you take permission from your doctor before doing so. Also, after being granted permission you should ensure to monitor the infant for any signs of side effects such as diarrhoea or skin rashes.

    • Does this affect liver function?

      Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use

    • Does this affect kidney function?

      Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:

      • Clcr 10-50 mL/minute: Administer every 6 hours.
      • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
      • Hemodialysis: Moderately dialyzable (20% to 50%).
      Consult your doctor before taking this medication.

    • Is It safe with alcohol?

      Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake

    What are the substitutes for Crocin Advance 500Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Crocin Advance 500Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The medication is administered only when required and therefore the chances of missing any dose are very likely. However, if you have been prescribed a scheduled regime then it is advised that you take your missed dose as soon as you remember it. But, if it is already time for the next dose then consider skipping the earlier dose.

    • Are there any overdose instructions?

      If you suspect that an overdose has occurred then notify your healthcare provider right away.

    How does this medication work?

    This is a pain relief medication that selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

      What are the interactions of Crocin Advance 500Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.
      • Interaction with Lab Test

        5-HIAA Urine Test

        You may get a false-positive result for this test if you take Crocin Advance 500Mg Tablet.
      • Interaction with Medicine

        One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced
      • Interaction with Disease

        Patients suffering from liver disease should use some other safer alternative.
      • Interaction with Food

        May slightly delay the absorption of extended-release preparations; the rate of absorption may be decreased when given with food high in carbohydrates

      FAQs about Crocin Advance 500Mg Tablet

      • Ques : What is Crocin Advance 500Mg Tablet?

        Ans : This is a medication that performs its action by obstructing the release of pain and fever chemical messengers.

      • Ques : What are the uses of Crocin Advance 500Mg Tablet?

        Ans : This medicine is used for the treatment and prevention from conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.

      • Ques : What are the Side Effects of Crocin Advance 500Mg Tablet?

        Ans : Allergic reaction, gastric ulcers, fatigue, anemia, nausea and vomiting are possible side effects.

      • Ques : What are the instructions for storage and disposal Crocin Advance 500Mg Tablet?

        Ans : This medicine should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : Should I use Crocin Advance 500Mg Tablet empty stomach, before food or after food?

        Ans : If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

      • Ques : How long do I need to use Crocin Advance 500Mg Tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, until the complete eradication of the disease. It is advised to use, till the time directed by your doctor.

      • Ques : Is there any food or drink I need to avoid?

        Ans : You can follow your normal diet under the usage of this medication.

      • Ques : Will Crocin Advance 500Mg Tablet be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses.

      • Ques : Can I take other medications along with Crocin Advance 500Mg Tablet?

        Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. This drug contains many combination medicines. If you use certain products together you may accidentally use too much of Crocin Advance 500Mg Tablet. Avoid drinking alcohol while taking this medication as it may increase the risk of liver damage.

      • Ques : Can I take Crocin Advance 500Mg Tablet with antibiotics?

        Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

      • Ques : Is Crocin Advance 500Mg Tablet an NSAID drug?

        Ans : No, this medication is not classified as an NSAID (nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.

      References

      • Crocin: Uses, Side Effects, Precautions, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 24 April 2019]. Available from:

        https://www.drugsbanks.com/crocin/

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      • 7 Select Acetaminophen- acetaminophen tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 23 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168da31e-de62-4280-9c66-2b41d2d93c31

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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