Deriphyllin Tablet

Deriphyllin Tablet is prescribed to patients who present with some of the most common symptoms associated with acute or chronic respiratory conditions where the patient might experience asthma, difficulty in breathing, wheezing and shortness of breath.

It also helps against chest tightness, breath shortness, interruption of breathing in newborn children, breathing difficulty, breathlessness, chronic asthma, whooping cough and several other conditions. Deriphyllin Tablet is manufactured by Zydus Cadila and contains the drugs named, Etofylline and Theophylline.

The recommended dose for the drug is 400 or 600 mg once a day in the morning or evening. A doctor’s prescription is not required to get this medicine and it can be obtained from any drug store. Deriphyllin helps the patient by relieving them of most of the above-mentioned symptoms, majorly by improving the flow of air in the air passages.

It also helps by reducing the difficulties faced while breathing. The primary working principle of the tablet is to inhibit the phosphodiesterase enzymes in the body, and in turn, by relaxing muscles and opening air passages, resulting in easy breathing.

Symptoms of overdose include nausea, vomiting, insomnia, irritability, tachycardia, seizures, tonic-clonic seizures, insomnia, and circulatory failure. If seizures have not occurred, induce vomiting; ipecac syrup is preferred.

Do not induce emesis in the presence of impaired consciousness. Repeated doses of charcoal have been shown to be effective in enhancing the total body clearance of theophylline. Do not repeat charcoal doses if an ileus is present.

Charcoal hemoperfusion may be considered if serum theophylline levels exceed 40 mcg/mL, the patient is unable to tolerate repeat oral charcoal administrations, or if severe toxic symptoms are present.

Clearance with hemoperfusion is better than clearance from hemodialysis. Administer a cathartic, especially if sustained release agents were used. Phenobarbital administered prophylactically may prevent seizures.

Take exactly as directed; do not exceed recommended dosage. Avoid smoking (smoking may interfere with drug absorption as well as exacerbate condition for which medication is prescribed).

If you are smoking when dosage is prescribed; inform prescriber if you stop smoking (dosage may need to be adjusted to prevent toxicity). Preferable to take on empty stomach (1 hour before or 2 hours after meals), with a full glass of water.

Avoid dietary stimulants (eg, caffeine, tea, colas, or chocolate - may increase adverse side effects). Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

• Asthma

• Bronchitis

• Chronic Obstructive Pulmonary Disorder (Copd)

• Allergy

• Throat Irritation

• Headache

• Nervousness

• Nausea

• Sleeplessness

• Gastric Pain

• Cns Toxicity

• How long is the duration of effect?

  The effect of the Deriphyllin is not clinically established.

• What is the onset of action?

  The effect of the Deriphyllin Tablet is not clinically established.

• Is it habit forming?

  No cases of habit forming has been reported as of now, making it a non-addictive medication.

• Is It safe with alcohol?

  It is not safe to consume alcohol while on this medication as you may start experiencing the problems like drowsiness, sleepiness and fatigue.

• Are there any pregnancy warnings?

  Since the ingredients of the medication include Etophylline and Theophyllin, it is advisable that pregnant women must not consume this medication as they both can cause hypersensitivity in women.

• Are there any breast-feeding warnings?

  The active ingredient Theophyllin reaches the infant through breast milk and thus can cause irritability and toxicity in the child. Therefore, it is important that nursing mothers not consume this medication at all.

• Does this affect kidney function?

  No relevant information is available. Kindly consult your doctor before taking this medication.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Dose adjustment may be needed in patients with moderate to severe liver disease. Please consult your doctor.

Below is the list of medicines, which have the same composition, strength and form as Deriphyllin Tablet , and hence can be used as its substitute.

• Agrophyllin 23 Mg/77 Mg Tablet

  Agron Remedies Pvt Ltd

• Are there any missed dose instructions?

  You should immediately take the missed dose the moment you remember but should avoid it, if it is the time of next dosage. It is necessary that you skip the missed dose in such cases and not double up the dosage next time.

• Are there any overdose instructions?

  You can take an overdose if you take two dosages in one go or increase the frequency of it. In cases of overdose, you must visit a doctor immediately as the side effects can cause serious health problems. Therefore, it is important that you stick the dosages as prescribed.

Deriphyllin medicine works by relaxing the muscles of the airways in the lungs. It also reduces the sensitivity of lungs to allergens that cause irritation and constriction of muscles in the chest and the lungs. It also causes bronchodilation by competitively inhibiting type III and type IV phosphodiesterase (PDE). PDE is an enzyme that leads to the breakdown of cyclic AMP in the smooth muscle cells. It also counters bronchoconstriction by binding to adenosine A2B receptors and antagonizing adenosine. Altogether it alleviates the symptoms of the condition.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Deriphyllin Tablet can interact with alcohol and produce negative results as it can aggravate the conditions of dizziness, drowsiness, blurred vision, loss of coordination and other such conditions.

• Interaction with Medicine

  You must consult a doctor if you are already taking medicines with Carbamazepine, Fluvoxamine, Phenytoin and Propranolol. The doctor will help you get the right dosage or ask you to stop one of the medication or give you a substitute for deryphillin.

• Interaction with Disease

  The interaction of the medicine can cause serious problems in cases like heart disorders, kidney related issues, liver diseases, seizures disorders, hypertension and so on. You must tell the doctor about your medical history so that they can prescribe you some substitute medicine and alter the dosages as well.

• Interaction with Food

  You must avoid food and beverages high in caffeine while consuming this medicine as it can cause some common side effects.

• Ques : What is Deriphyllin Tablet?

  Ans : Deriphyllin is a medication consist of Etophylline and Theophylline. This medication works by calming the muscles down and opening air passages and preventing the phosphodiesterase enzymes. It is also used for the difficulties in Breathing, Asthma, Wheezing, Chest tightness and other conditions.

• Ques : What are the side effects of Deriphyllin Tablet?

  Ans : Deriphyllin has some most commonly known side effects, which are :

  • Anxiety,
  • Anorexia,
  • Abdominal pain,
  • Stomach upset,
  • Trembling or shaking,
  • Irritability,
  • Insomnia,
  • Chest pain or discomfort,
  • Irregular heart beat,
  • Sweating,
  • Low blood pressure, Vomiting.

• Ques : Can I take Deriphyllin Tablet If I am Pregnant?

  Ans : Deriphyllin Tablet has Etophylline and Theophylline as active ingredients, Which is contraindicated during pregnancy as it causes hypersensitivity in pregnant women. FDA(Food and Drug Administration) has determined Theophylline in pregnancy category C, which specifies that there was some fetal harm in animals and there is no data which shows Deriphyllin tablet is safe for women in pregnancy.

• Ques : Is Deriphyllin Tablet safe during breastfeeding?

  Ans : Deriphyllin Tablet has two active ingredients known as Etophylline and Theophylline, from which Theophylline is the ingredient which is present in the breast milk and passes from mother to the Infant. It is found in a huge quantity in the breast milk which may cause infant irritability. Deriphyllin is not suggested while breastfeeding because it can cause mild toxicity. The estimated amount of Theophylline consumed by the infant is 20 mg per liter of breast milk.

• Ques : When Deriphyllin Tablet should be taken?

  Ans : It is advised to take this medication on an empty stomach. Consume it an hour before taking food or 2 hours after taking food.

• Ques : Can Deriphyllin Tablet be used for difficulty in breathing and asthma?

  Ans : Yes, this medication can treat breathing difficulties and asthma. It is important to consult the doctor before using it and inform about the previous medications.

• Ques : How long should I take Deriphyllin Tablet?

  Ans : It is observed that Deriphyllin may take 4-5 weeks to show full potency. It also depends upon the patient’s health conditions. Therefore, it is advised to consult a medical practitioner for the correct duration of usage.

• Ques : How frequently I can take Deriphyllin Tablet?

  Ans : It is advised to consume once or twice in a day. It is a prescribed medication, therefore it is suggested to ask the doctor for the proper dosage.

• Theophylline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 May 2017]. Available from:

  https://www.drugbank.ca/drugs/DB00277

• DailyMed - Theophylline tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f2a4716-34fe-4a2c-8bbf-5ed16772a967

• Theophylline | C7H8N4O2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

  https://pubchem.ncbi.nlm.nih.gov/compound/2153#section=Top

• Etofylline [Internet].Pubchem.ncbi.nlm.nih.gov. 2019 [cited 4 March 2019]. Available from:

  https://pubchem.ncbi.nlm.nih.gov/compound/etofylline#