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Overview

Epalrestat

Prescription vs OTC : Prescription by Doctor required

About Epalrestat

Epalrestat, is a derivative of carboxylic acid which is used for hyperglycemic related complications like neuropathy, retinopathy or nephropathy. This medicine reduces intracellular sorbitol accumulations significantly. There is an improvement in the morphological abnormalities of the nerves once a diabetic is treated with this medicine.

Epalrestat, cannot be used in case one is hypersensitive, which is a contraindication. This cannot be used in case you suffer from severe hepatic insufficiency. You need to consult a doctor before taking this medicine in case you are breast feeding or are pregnant.

Epalrestat, is taken orally, with the dosage depending on your medical condition and response to the treatment. This should not be missed or discontinued at your own will. The medicine has to be taken at fixed times so that the medicine is effective and sustains the body balance of the patient.

It causes dizziness, drowsiness, hyper tension and may cause severe headaches. Thus one should not take this medicine if one is driving or working on heavy machinery. The other side effects may be hepatic dysfunction, vomiting, gastric discomfort, eruptions, exacerbation of renal function, numbness, edema or diarrohea.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the uses of Epalrestat

    • Diabetic Nerve Disease

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the side effects of Epalrestat ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Key highlights of Epalrestat

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Epalrestat, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Medicines containing Epalrestat

    Below is the list of medicines, which contains Epalrestat as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    How does this medication work?

    The medication is a reversible inhibitor for aldose reductase, which slows down the functionality of the said enzyme.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

      References

      • Epalrestat-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/epalrestat

      • Epalrestat-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 10 June 2022].Available from:

        https://go.drugbank.com/drugs/DB15293

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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