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Overview

Esokem D 30 Mg/40 Mg Capsule

Manufacturer :  Alkem Laboratories Ltd
Medicine Composition :  Domperidone, Esomeprazole
Prescription vs OTC : Prescription by Doctor not required

About Esokem D 30 Mg/40 Mg Capsule

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Esomeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Esokem D 30 Mg/40 Mg Capsule is a combination of Domperidone and Esomeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Esokem D 30 Mg/40 Mg Capsule if you have the following conditions:

  • An allergy to Esokem D 30 Mg/40 Mg Capsule or any other ingredient of this medicine
  • Bleeding problems or blockage in your stomach or in the intestine
  • Tumour in the pituitary gland
  • Cardiac disease
  • Incorrect levels of magnesium, potassium or calcium in the blood
  • Severe/moderate liver impairment

    What are the uses of Esokem D 30 Mg/40 Mg Capsule

    • Gastroesophageal Reflux Disease

    • Peptic Ulcer

    What are the contraindications of Esokem D 30 Mg/40 Mg Capsule ?

    • Allergy

    • Tumor Of Pituitary Gland

    • Heart Diseases

    What are the side effects of Esokem D 30 Mg/40 Mg Capsule ?

    Key highlights of Esokem D 30 Mg/40 Mg Capsule

    • How long is the duration of effect?

      The effect of this medicine lasts up to 6 hours.

    • What is the onset of action?

      The peak effect of this tablet can be observed within 30 to 60 minutes of administration.

    • Are there any pregnancy warnings?

      This medicine should be avoided by pregnant women unless suggested by the doctor.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      Breastfeeding women must take medical help before using this medication.

    What are the substitutes for Esokem D 30 Mg/40 Mg Capsule ?

    Below is the list of medicines, which have the same composition, strength and form as Esokem D 30 Mg/40 Mg Capsule , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

    • Are there any overdose instructions?

      Contact your doctor if an overdose is suspected.

    How does this medication work?

    This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      What are the interactions of Esokem D 30 Mg/40 Mg Capsule ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

        Medicine

        This medication interacts with Ketoconazole, Methotrexate, Warfarin, Nelfinavir and others.
      • Interaction with Disease

        Disease

        This medication interacts with Osteoporosis, Liver disease and Hypomagnesemia.

      FAQs about Esokem D 30 Mg/40 Mg Capsule

      • Ques : What is Esokem D 30 Mg/40 Mg Capsule?

        Ans : This medication is a combination of Domperidone and Esomeprazole. The drug belongs to the class of drugs known as dopamine antagonists and PPI, respectively. It contains domperidone and esomeprazole as active ingredients.

      • Ques : What are the uses of Esokem D 30 Mg/40 Mg Capsule?

        Ans : Esokem is used for the treatment and prevention from conditions such as Erosive Esophagitis, Gastroesophageal Reflux Disease, and Helicobacter pylori Infection.

      • Ques : What are the Side Effects of Esokem D 30 Mg/40 Mg Capsule?

        Ans : Side effects include Headache, Nausea, Flatulence, Stomach pain, Skin rash, Swelling and redness at the injection site, Difficulty in breathing, Swelling of face, lips, eyelids, tongue, hands and feet , Irregular heartbeat, Severe diarrhea, Unusual tiredness and weakness, Fever, and Decreased appetite.

      • Ques : What are the instructions for storage and disposal Esokem D 30 Mg/40 Mg Capsule?

        Ans : Store Esokem D 30 mg 40 mg capsule in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children.

      • Ques : How long do I need to use Esokem D 30 Mg/40 Mg Capsule before I see improvement of my conditions?

        Ans : It is a medicine which takes 1 or 2 days before you see an improvement in your health conditions.

      • Ques : What are the contraindications to Esokem D 30 Mg/40 Mg Capsule?

        Ans : This medication should not be used if you have the conditions such as Do not chew or crush the tablets, Hypersensitivity to domperidone, Moderate or severe hepatic impairment, Patients with significant electrolyte disturbances, Pregnancy, etc.

      • Ques : Is Esokem D 30 Mg/40 Mg Capsule safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

      • Ques : Will Esokem D 30 Mg/40 Mg Capsule be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as Headache, Somnolence, Akathisia, Diarrhea, Rash, Pruritus, Breast enlargement, Breast tenderness, Galactorrhoea, Amenorrhea, Breast pain, Menstruation irregular, etc.

      References

      • Esomeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/esomeprazole

      • Esomeprazole- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00736

      • Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

      • Domperidone- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01184

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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