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Overview

Espin 1.25 MG Tablet

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  S-Amlodipine
Prescription vs OTC : Prescription by Doctor required

About Espin 1.25 MG Tablet

Espin 1.25 MG Tablet is known to be a calcium channel blocker. Thus, it effectively treats hypertension and angina, that is, pain in the chest. The drug reduces the effect of calcium in the body, increasing blood flow to and from the heart as well as the blood vessels in the body. This in turn helps lower blood pressure of the body, regulate erratic heartbeat and relaxes the heart.

The dosage of Espin 1.25 MG Tablet and the duration it needs to be taken for, depends on the extent of your condition. The drug can be taken orally either with food or without. The drug should be swallowed whole. Espin 1.25 MG Tablet is most effective when it is not chewed or crushed. It is most effective if the entire prescribed course is completed.

Espin 1.25 MG Tablet has a few side effects which include

These side effects are mostly minor and disappear in some time. If they persist or become more severe it is best to seek medical aid immediately. Over dosage of Espin 1.25 MG Tablet can result in peripheral vasodilation, causing hypotension.

Alcohol consumption should be avoided if you are taking this drug. Liquor can interfere with the effects of the drug. Espin 1.25 MG Tablet is also not prescribed for pregnant and lactating women. Espin 1.25 MG Tablet is known to negatively affect the fetus.

Patients with kidney and liver problems should inform their doctor about their condition and take the drug as per doctor’s advice. Espin 1.25 MG Tablet is known to cause dizziness, thus it is advised that driving should be avoided. To prevent sudden bouts of dizziness patients should move slowly when getting up or getting out of bed.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the uses of Espin 1.25 MG Tablet

    • Hypertension

      Espin 1.25 MG Tablet is used in the treatment of hypertension which is an increase in the blood pressure caused by genetic and environmental factors.

    • Angina Pectoris

      Espin 1.25 MG Tablet is used in the treatment of Angina Pectoris which is a type of heart disease characterized by chest pain caused due to emotional stress and smoking.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the contraindications of Espin 1.25 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the side effects of Espin 1.25 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Key highlights of Espin 1.25 MG Tablet

    • How long is the duration of effect?

      This effect of this medicine lasts for a duration of approximately 24 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 6 to 12 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is It safe with alcohol?

      Caution must be practiced while consuming alcohol along with this medicine. Kindly consult your doctor.

    • Is it safe to drive while on this medicine?

      May cause drowsiness; use caution when driving or engaging in tasks that require alertness until response to drug is known.

    • Does this affect kidney function?

      It is found to be safe to be used in patients with kidney disease. Adjustment of dose is not needed. Kindly consult with your doctor for further details.

    • Does this affect liver function?

      Caution must be taken while using this medicine in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the substitutes for Espin 1.25 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Espin 1.25 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    Where is the Espin 1.25 MG Tablet approved?

    • India

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

    How does this medication work?

    This medication belongs to the class of a calcium channel blocker. It works by inhibiting the entry of calcium into the cardiac and vascular smooth muscles and prevents the contraction of the muscles and thereby reduces the blood pressure.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

      What are the interactions of Espin 1.25 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Calcium may reduce the calcium channel blocker's effects, particularly hypotension.
        • Rifampin increases the metabolism of calcium channel blockers; adjust the dose of calcium channel blocker to maintain efficacy.
      • Interaction with Disease

        Increased angina and/or MI has occurred with initiation or dosage titration of calcium channel blockers. Use caution in severe aortic stenosis. Use caution in patients with severe hepatic impairment. Safety and efficacy in children have not been established. Dosage titration should occur after 7-14 days on a given dose.
      • Interaction with Food

        Consumption of grapefruit juice is not recommended as it increases the concentration of Espin 1.25 MG Tablet. Inform the doctor if you experience dizziness, headache, swelling of hands and feet is necessary.

      References

      • Amlodipine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/amlodipine

      • Amlodipine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00381

      • AMLODIPINE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=AMLODIPINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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