Hamostat 500mg Injection

Epsilon-aminocaproic acid - EACA is an “antifibrinolytic.” This means that EACA interferes with the body’s natural mechanisms for removing blood clots; in other words, it makes blood clots last longer.

Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. It is the only potent antifibrinolytic agent which is commercially available in the United States.A more effective use of EACA involves prevention of post-surgical bleeding in greyhounds and related breeds. Unfortunately, greyhounds are commonly affected with bone cancer requiring limb amputation. A common scenario would be that the surgery would go well but several days later bleeding would occur at the surgery site. It appears that some greyhounds have a problem with maintaining normal blood clots and these clots are dissolving prematurely. Giving EACA appears to inhibit clot-dissolving enzymes thus allowing the clot to stay in place normally. EACA could be given preventively in anticipation of possible bleeding or after problems have occurred to set things right.There are many conditions that involve unwanted hemorrhage: surgical procedures where bleeding is high risk, inoperable tumors that tend to bleed spontaneously etc. The applications of a medication that helps to maintain blood clots appear to extend well beyond greyhounds having limb amputations.

EACA can be used as an oral medication post - operatively to discourage bleeding or as an intravenous infusion before or after surgery to discourage excessive bleeding. EACA may be used in the treatment of spontaneously bleeding tumors as well. Approximately 1% of patients report upset stomach with this medication. EACA should not be used in patients who have intravascular abnormal blood clotting problems or who have a history of stroke or vascular accident. These patients already have an increased tendency to clot an abnormal or excessive manner and should not have this potential further increased.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Bleeding

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Nausea

• Vomiting

• Diarrhoea

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Hamostat 500mg Injection may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Hamostat 500mg Injection is probably usafe to use during lactation. \nAnimal or human data is not available.

• Is it safe to drive while on this medicine?

  It is not known whether Hamostat 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

• Does this affect kidney function?

  Hamostat 500mg Injection is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
  Caution should be advised in patients with renal impairment.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Hamostat 500mg Injection, skip it and continue with your normal schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Hamostat 500mg Injection is an antifibrinolytic agent which acts by reversibly binding plasminogen, blocking its interaction with fibrin. This reduces fibrinolysis, thereby reducing excessive bleeding after surgery. It can also change apoliprotein (a) conformation and binding properties and also preventing its formation.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.