Inderal 40 MG Tablet

Inderal 40 MG Tablet is used for the management of high blood pressure (hypertension), angina pectoris, pheochromocytoma, essential tremor, tetralogy of Fallot cyanotic spells, and arrhythmias (such as atrial fibrillation and flutter, A-V nodal re-entrant tachycardias, and catecholamine-induced arrhythmias).

It is also used in the prevention of myocardial infarction, migraine headache. Inderal 40 MG Tablet is also helpful in treating the prevention of myocardial infarction, migraine headache.

This medication is a beta-blocking agent that attaches itself to the heart and inhibits the regular molecules from triggering the receptors. It blocks the beta-adrenergic receptors in the heart, thus slowing your heartbeat down and lowering the blood pressure. This lowers the stress placed on your heart, arteries, veins and blood vessels, decreasing the workload of the heart.

The medicine might not be suitable for everyone as it can have harmful effects on people with certain conditions. Before beginning a course of this medication, you need to notify your doctor if you are-

• Pregnant or breastfeeding, or
• Suffering from conditions such as:
• Asthma,
• Diabetes mellitus,
• Psoriasis,
• Liver or kidney problems,
• Severe heart condition.

The medicine must be taken according to the doctor’s prescription. The doctor might recommend taking it two, three or even four times a day. You must complete the course of this medication otherwise it can cause you to develop withdrawal symptoms.

• Hypertension

• Anxiety

• Chest Pain

• Angina Pectoris

• Allergy

• Sinus Bradycardia

• Cardiogenic Shock

• Pregnancy

• Chest Pain

• Hypotension

• Cardiogenic Shock

• Light Headedness

• Confusion

• Dizziness

• Insomnia

• Fatigue

• Lethargy

• Cold Extremities

• Vertigo

• Syncope

• Hallucination

• Rash

• Alopecia

• Pruritus

• Urticaria

• Contact Dermatitis

• Diarrhoea

• Nausea

• Vomiting

• Stomach Discomfort

• Anorexia

• How long is the duration of effect?

  The effect of this medicine lasts for about 9 hours of duration.

• What is the onset of action?

  The effect of this medicine can be observed within an hour of administration.

• Are there any pregnancy warnings?

  Use of this medicine is not recommended for use in pregnant women.

• Is it habit forming?

  Mild to moderate habit forming tendencies have been reported and hence requires careful administration and withdrawal.

• Are there any breast-feeding warnings?

  You should consult your doctor and discuss the potential benefits and risks before deciding to take this medicine during breastfeeding.

• Is It safe with alcohol?

  Consumption of alcohol along with Propranolol is found to be unsafe. Thus it should be avoided.

• Is it safe to drive while on this medicine?

  This medicine might affect the alertness of the patient. Thus driving must be avoided if you face any symptoms related to it.

• Does this affect kidney function?

  This medicine is found to be safe to use in patient with kidney disease. Adjustment of dose is not needed.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Inderal 40 MG Tablet , and hence can be used as its substitute.

• Provanol 40 MG Tablet

  Intas Pharmaceuticals Ltd

• Cardimol 40 MG Tablet

  Mankind Pharmaceuticals Ltd

• Inderal La 40 MG Tablet

  Abbott India Ltd

• Manoprolol 40 MG Tablet

  Orchid Chemicals & Pharmaceuticals Ltd

• Ciplar 40 MG Tablet

  Cipla Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember.

• Are there any overdose instructions?

  Report any incidence of overdose to the doctor immediately.

The exact mechanism of action of this drug for all the indications is not established. However, this medicine non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the use of alcohol while you are taking this medicine. Any activity requiring a high level of mental alertness like operating heavy machinery or driving should be avoided.

• Interaction with Medicine

  • Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
  • Antipyrine's clearance is reduced by 30% to 40%.
  • Cimetidine increases the plasma concentration of Inderal 40 MG Tablet and its pharmacodynamic effects may be increased.
  • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
  • Epinephrine (including local anesthetics with epinephrine): Inderal 40 MG Tablet may cause hypertension.
  • Flecainide: Pharmacological activity of both agents may be increased when used concurrently.
  • Fluoxetine may inhibit the metabolism of Inderal 40 MG Tablet, resulting in cardiac toxicity.
  • Glucagon: Inderal 40 MG Tablet may blunt hyperglycemic action.
  • Haloperidol: Hypotensive effects may be potentiated.
  • Hydralazine: The bioavailability propranolol (rapid release) and hydralazine may be enhanced with concurrent dosing.
  • Insulin: Inderal 40 MG Tablet inhibits recovery and may cause hypertension and bradycardia following insulin-induced hypoglycemia. Also masks the tachycardia that usually accompanies insulin-induced hypoglycemia.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use of both.

• Interaction with Food

  Information not available.

• Interaction with Disease

  • Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of propranolol in CHF has not been demonstrated).
  • Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
  • Use caution in patient with PVD.
  • Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms.
  • Can mask signs of thyrotoxicosis.
  • Can cause fetal harm when administered in pregnancy.
  • Use cautiously in hepatic dysfunction (dosage adjustment required).
  • Use care with anesthetic agents which decrease myocardial function.

• Ques : What is Inderal 40 MG Tablet?

  Ans : Inderal tablet is a medication which has Propranolol as an active ingredient present in it. This medicine performs its action by controlling high blood pressure.

• Ques : What are the uses of Inderal 40 MG Tablet?

  Ans : Inderal tablet is used for the treatment and prevention from conditions and symptoms of diseases like hypertension, angina pectoris, migraine attacks and high blood pressure.

• Ques : What are the Side Effects of Inderal 40 MG Tablet?

  Ans : Dizziness, skin blistering, hypotension, weight gain and chest pain are common side effects.

• Ques : What are the instructions for storage and disposal Inderal 40 MG Tablet?

  Ans : Inderal 40 mg should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Inderal 40 MG Tablet empty stomach, before food or after food?

  Ans : The salts involved in this medication, work properly on an empty stomach.

• Ques : How long do I need to use Inderal 40 MG Tablet before I see improvement of my conditions?

  Ans : In most of the cases, the average time taken by Inderal tablet to reach its peak effect is around 3 days to 3 months, before noticing an improvement in the condition.

• Ques : Is there any food or drink I need to avoid?

  Ans : The diet should be normal, there is nothing as such to avoid. However, eating healthy, doing physical exercises and avoiding any kind of harmful practices like smoking or drinking can uplift your health.

• Ques : Will Inderal 40 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : There is no need to take Inderal tablet more than its recommended doses.