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Overview

Irinotecan

Prescription vs OTC : Prescription by Doctor required

About Irinotecan

Irinotecan helps in the treatment of cancer. The drug prevents the multiplication and spread of cancer cells. Medical professionals use this drug to treat cancer of the colon or rectum. It is specifically a combination drug, and is prescribed with other cancer medicines during chemotherapy.

Before the doctor begins chemotherapy using this drug, provide him with a detailed medical history. Inform him about any current problems that you may be suffering from, especially if you have kidney or liver issues, diabetes, Gilbert’s syndrome, asthma or intestinal problems. The drug is not meant to be used in cancer treatment for women patients who are pregnant. Breast feeding mothers should also consult their doctor before starting treatment.

A DNA test may be done before the treatment commences. It is generally administered via an IV for about 90 minutes.

The most common side effect of Irinotecan is diarrhea, which can even become life threatening if it leads to dehydration. Doctors generally subscribe medicines to prevent the onset of this side effect. Other side effects include- anxiety, chills, confusion, tightness or pain in the chest, cough and hoarse voice, fever, dizziness etc.

Some very rare side effects that one may experience are hives, sudden gain weight, rise in blood pressure and swelling of the face, eyes and lips.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Irinotecan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Irinotecan ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Irinotecan

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Torsirin 100mg/5ml injection is unsafe to use during pregnancy.
      There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Torsirin 100mg/5ml injection is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Patients may experience undesirable effects likedizziness and blurred vision, at the start of treatment and should avoid driving vehicles or using machines.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Irinotecan, please consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Medicines containing Irinotecan

    Below is the list of medicines, which contains Irinotecan as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    This medication falls under the category of a chemotherapy drug used for metastatic and rectal cancer. It is an antineoplastic enzyme inhibitor. It is administered through intravenous lines which works by blocking the enzyme topoisomerase I. This enzyme is needed by cells to grow and divide, thereby preventing cancer cells to grow.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      References

      • Irinotecan-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 17 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/irinotecan

      • Irinotecan-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 17 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00762

      • IRINOTECAN injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 17 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=IRINOTECAN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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