Kufril LS Syrup

Kufril syrup is an active mucolytic agent that treats coughs with mucus. Its ingredients are Ambroxol (15 mg), Levosalbutamol (0.5 mg) and Guaifenesin (50 mg). Ambroxol is a mucokinetic agent that makes the sputum thinner and easily removable by coughing.

Levosalbutamol is an adrenergic receptor antagonist that smoothes the respiratory muscles and eases air in and out of the lungs. Guaifenesin is an expectorant; it clears chest congestion. It thins the mucus in the air passageway to make it easier to cough up the mucus and decongest the chest.

It is used in the treatment of cough, acute and chronic bronchopulmonary problems, abnormal mucus secretion, chest congestion, thick mucus, constricted airways, inflammation of lungs and sore throat.

It is an anti-inflammatory and anti-oxidant anaesthetic which improves the patient’s conditions by relaxing the muscles in the airways, thinning mucus and reducing phlegm in the respiratory passage.

For adults, the usual dosage is 30 to 120 mg per day, taken twice or thrice a day, according to the doctor’s recommendation. It is usually recommended to take the syrup after food.

• Cough

• Bronchospasm

• Pregnancy

• Headache

• Dizziness

• Nausea Or Vomiting

• Diarrhoea

• Severe Skin Allergy

• Skin Rash

• Tremor

• Is It safe with alcohol?

  Consumption of alcohol while on this medication induces dizziness.

• Are there any pregnancy warnings?

  Pregnant women must consult doctor before using this drug.

• Are there any breast-feeding warnings?

  Proceed with caution, if you are breastfeeding. Discuss the benefits and risks with your physician.

• Is it safe to drive while on this medicine?

  If you are suffering side-effects like headaches, drowsiness and dizziness, it is unsafe to drive.

• Does this affect kidney function?

  There are no reports regarding the medicine and kidney functioning. Consult your doctor.

• Does this affect liver function?

  Consult your physician about any potential risks to your liver functioning.

• How long is the duration of effect?

  The effects of this syrup last for an average of 8-12 hours.

• What is the onset of action?

  It takes an average of 1-2 hours to produce its effects.

• Is it habit forming?

  It is not habit-forming.

Below is the list of medicines, which have the same composition, strength and form as Kufril LS Syrup , and hence can be used as its substitute.

• Usal Ls Syrup

  Seagull Labs (I) Pvt Ltd

• Brozeet Ls Syrup

  Alembic Pharmaceuticals Ltd

• Tuspel LS 15 mg/0.5 mg/50 mg Syrup

  Indoco Remedies Ltd

• Piritexyl-Ls Junior Expectorant

  Jenburkt Pharmaceuticals Ltd

• Bronkolyte Levo PD Syrup

  Entod Pharmaceuticals Ltd

• Sulung Pd 15 Mg/0.5 Mg/50 Mg Expectorant

  Anglo-French Drugs & Industries Ltd

• Brozeet Plus 15 Mg/0.5 Mg/50 Mg Syrup

  Alembic Pharmaceuticals Ltd

• Altime LS 15 mg/0.5 mg/50 mg Syrup

  S H Pharmaceuticals Ltd

• Cleartuss Ls Syrup

  Cadila Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. However, do not double dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

It is an agent that causes diffusion of thick mucus. Uncontrolled quantity of nitric oxide (NO) is related to inflammation and other kinds of disruptions of the functioning of the airways. It inhibits the activation of guanylate cyclase which is nitric oxide dependent. Simultaneously, it works as a β2 adrenergic receptor that results in increase of cyclic AMP. Increased AMP leads to activation of protein kinase A which again prevents phosphorylation of myosin. All this mechanism leads to relaxation of smooth muscles. It also reduces adhesiveness and surface tension of congealed mucus in upper respiratory tract to increase flow of mucus, stimulating and increasing efficiency of the cilia to remove the accumulated mucus.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Medicine

  It interacts adversely with antibiotics, Bendroflumethiazide, Carvedilol, Nadolol, Sotalol and Timolol. These drugs change the effects of Kufril or produce severe side-effects.

• Interaction with Disease

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  Kufril has adverse interactions in patients with liver and kidney impairment. It is recommended to alter the dosage of the syrup for safety.

• Ques : What is Kufril LS Syrup?

  Ans : It is medication which has Ambroxol, Guaiphenesin and Levosalbutamol as active elements present in it. This medication performs its action by relaxing the muscles in the airways, helps in clearing the mucus, contains anti-inflammatory, antioxidant, and also have local anaesthetic effects, restricting the phlegm in the air wawww.lybrate.com/medicine/ys.

• Ques : What is the use of Kufril LS Syrup?

  Ans : This drug is used to treat cough, bronchospasm, etc.

• Ques : What are the side effects of Kufril LS Syrup?

  Ans : Side effects include diarrhea, dizziness, headache, etc.

• Ques : Can Kufril LS Syrup be used for cough and acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion?

  Ans : Yes, it is a medication which is used for the conditions such as cough and acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion.

• Ques : How long do I need to use Kufril LS Syrup before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

• Ques : At what frequency do I need to use Kufril LS Syrup?

  Ans : It is generally used twice or thrice a day, as the time interval to which this medication has an impact, is around 8 to 12 hours, but it is not the standard frequency, for using this medication.

• Ques : Should I use Kufril LS Syrup empty stomach, before food or after food?

  Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for the storage and disposal of Kufril LS Syrup?

  Ans : It contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

• Ambroxol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/ambroxol

• Levalbuterol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/levosalbutamol

• Medicines For Cough- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 23 April 2019]. Available from:

  https://www.drugsbanks.com/medicines-for-cough/

• Guaifenesin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/guaifenesin