Levomac 500 MG Tablet

Levomac 500 MG Tablet is a medicine that is a member of the fluoroquinolone antibiotic family. It fights against bacterial infections like tuberculosis, pneumonia, laryngitis, cellulitis, gastroenteritis, acute or chronic bronchitis, urinary tract infections, tonsillitis, anthrax and plague. This antibiotic also treats infections of the pelvis, kidney, prostate and skin.

Levomac 500 MG Tablet may also be used for uncomplicated skin and skin structure infection (due to S. aureus or S. pyogenes) and complicated urinary tract infection due to gram-negative Enterobacter sp, including acute pyelonephritis (caused by E. coli).

Levomac 500 MG Tablet works by killing the bacteria that are causing an infection. It hinders the process of cell replication and cell division, within the cell of the bacteria, by inhibiting the synthesis of the DNA gyrase enzyme. Without this enzyme, the cell of the bacteria cannot survive or grow. Hence, Levomac 500 MG Tablet behave as bactericide.

Levomac 500 MG Tablet fights against bacteria that are Gram-positive as well Gram-negative. This broad-spectrum antibiotic is effective in inhibiting the synthesis of enzymes called DNA gyrase, which is essential to the process of replication and division of bacterial cells. Thus, Levomac 500 MG Tablet inhibits the cell division of the bacteria, making it impossible for them to survive. This makes it effective in treating bacterial infections.

The doctor will prescribe instructions for taking Levomac 500 MG Tablet according to your condition, the severity of that condition and the other medications you are taking. It is important to complete the course that the doctor prescribes, even if the symptoms disappear, or else the infection might recur. Do not double up the dosage to make up for a forgotten one, as an excess of this medicine can lead to overdosing.

This antibiotic can be harmful for children, breast-feeding mothers and pregnant women. Therefore, it is advisable for them not to take Levomac 500 MG Tablet. In some cases, for patients suffering from certain other conditions, it is advisable not to take Levomac 500 MG Tablet.

You should inform your doctor before beginning a prescription of Levomac 500 MG Tablet If you also suffer from conditions like-

• Myasthenia gravis,
• Heart disease,
• Liver damage,
• Tendonitis,
• Kidney failure and Diabetes.

Although this rarely occurs, it is possible, for you to have an allergy to Levomac 500 MG Tablet. An allergic reaction would cause symptoms such as hives, swollen lips, face or tongue, severe skin rashes, sore throat, rapid heart rate and difficulty breathing. It is advisable to stop taking this medicine immediately, if you experience the symptoms of an allergic reaction and consult with your doctor.

Symptoms of overdose include acute renal failure, seizures. Treatment should include GI decontamination and supportive care; not removed by peritoneal or hemodialysis.

Take per recommended schedule, preferably on an empty stomach (1 hour before or 2 hours after meals). Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). Take complete prescription; do not skip doses. Do not take with antacids; separate by 2 hours.

• Sinusitis

• Urinary Tract Infection

• Chronic Bronchitis

• Community Acquired Pneumonia

• Skin And Structure Infection

• Pyelonephritis

• Allergy

• Pregnancy

• Dizziness

• Headache

• Insomnia

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Tremor

• Arthralgia

• Hypertension

• Bradycardia

• Tachycardia

• Seizures

• Thrombocytopenia

• Jaundice

• Acute Renal Failure

• Arrhythmia

• How long is the duration of effect?

  This medicine is excreted largely in urine and the effect lasts for a duration of 16 to 20 hours.

• What is the onset of action?

  The effect can be observed within 1 to 3 hours of administration of the dose.

• Are there any pregnancy warnings?

  This medicine is generally not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for women who are breastfeeding as it affects the development of infant's joints. Use only if clearly needed under the supervision of a doctor. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

• Is It safe with alcohol?

  It is safe to consume alcohol with this medicine.

• Is it safe to drive while on this medicine?

  This medicine affects the consciousness of the patient. Thus driving must be avoided while taking this medication.

• Does this affect kidney function?

  Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Kindly consult your doctor before taking it. Dosing adjustment in renal impairment:

  • Clcr 20-49 mL/minute: Administer 250 mg every 24 hours (initial: 500 mg).
  • Clcr 10-19 mL/minute: Administer 250 mg every 48 hours (initial: 500 mg for most infections; 250 mg for renal infections).
  • Hemodialysis/CAPD: 250 mg every 48 hours (initial: 500 mg).

• Does this affect liver function?

  Limited information is available regarding its use in patients with liver disease. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Levomac 500 MG Tablet , and hence can be used as its substitute.

• Levosure 500 MG Tablet

  Mankind Pharmaceuticals Ltd

• Levotab 500 MG Tablet

  Intas Pharmaceuticals Ltd

• Lazanol 500 MG Tablet

  Novartis India Ltd

• Zilee 500 MG Tablet

  Fdc Ltd

• Levober 500 MG Tablet

  Calibar Pharmaceuticals

• Are there any missed dose instructions?

  The missed dose should be taken immediately.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Interaction with alcohol is unknown.

• Interaction with Lab Test

  Evaluation of organ system functions (renal, hepatic, ophthalmologic, and hematopoietic) is recommended periodically during therapy; the possibility of crystalluria should be assessed; WBC and signs of infection.

• Interaction with Medicine

  • Antineoplastic agents may decrease the absorption of quinolones.
  • Cimetidine, and other H2 antagonists may inhibit renal elimination of quinolones.
  • Foscarnet has been associated with an increased risk of seizures with some quinolones.
  • Loop diuretics: Serum levels of some quinolones are increased by loop diuretic administration. May diminish renal excretion.
  • NSAIDs: The CNS stimulating effect of some quinolones may be enhanced, resulting in neuroexcitation and/or seizures.
  • Probenecid: Blocks renal secretion of quinolones, increasing concentrations.
  • Warfarin: The hypoprothrombinemic effect of warfarin is enhanced by some quinolone antibiotics. Levofloxacin does not alter warfarin kinetics, but may alter the gastrointestinal flora. Monitor INR closely during therapy.

• Interaction with Disease

  Not recommended in children <18 years of age; other quinolones have caused transient arthropathy in children; CNS stimulation may occur (tremor, restlessness, confusion, and very rarely hallucinations or seizures); use with caution in patients with known or suspected CNS disorders or renal dysfunction; prolonged use may result in superinfection; if an allergic reaction (itching, urticaria, dyspnea, pharyngeal or facial edema, loss of consciousness, tingling, cardiovascular collapse) occurs, discontinue the drug immediately; use caution to avoid possible photosensitivity reactions during and for several days following fluoroquinolone therapy; pseudomembranous colitis may occur and should be considered in patients who present with diarrhea.

• Ques : What is Levomac 500 mg tablet?

  Ans : This tablet belongs to the fluoroquinolone antibiotic family of drugs. It is an antibiotic and contains Levofloxacin as an active ingredient.

• Ques : What are the uses of Levomac 500 mg tablet?

  Ans : This medicine is used for the treatment and prevention of diseases like cystitis, pyelonephritis, nongonococcal urethritis, and skin infection.

• Ques : What are the Side Effects of Levomac 500 mg tablet?

  Ans : Possible side-effects include diarrhea, abdominal pain, confusion, fever, and redness of the skin.

• Ques : What are the instructions for storage and disposal Levomac 500 mg tablet?

  Ans : This tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : What are the contraindications to Levomac 500 MG Tablet?

  Ans : This medication should not be used if you have the following conditions such as tremors, restlessness, anxiety, lightheadedness, confusion, hallucinations, paranoia, depression, etc.

• Ques : Is Levomac 500 MG Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

• Ques : Will Levomac 500 MG Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose can lead to increased chances of side effects.

• Ques : Is Levomac 500 MG Tablet safe?

  Ans : Levomac 500 MG Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose.

• Ques : What if I forget to take a dose of Levomac 500 MG Tablet?

  Ans : If you forget a dose of Levomac 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time.

• Ques : Can the use of Levomac 500 MG Tablet cause diarrhea?

  Ans : Yes, the use of Levomac 500 MG Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria.

• Ques : Can I stop taking Levomac 500 MG Tablet when I feel better?

  Ans : No, do not stop taking Levomac 500 MG Tablet and complete the full course of treatment even if you feel better.

• Ques : Can the use of Levomac 500 MG Tablet increase the risk of muscle damage?

  Ans : Yes, the use of Levomac 500 MG Tablet is known to increase the risk of muscle damage, commonly in the ankle. Inform your doctor if you feel any kind of muscle pain while using this medicine.