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Overview

Lonazep 0.25 MG Tablet

Manufacturer :  Sun Pharma Laboratories Ltd
Medicine Composition :  Clonazepam
Prescription vs OTC : Prescription by Doctor not required

About Lonazep 0.25 MG Tablet

Lonazep 0.25 MG Tablet is used to prevent as well as treat seizures. This medicine is referred to as an antiepileptic. Also known as anti-convulsant, Clonazepam helps to control panic attacks. The medication falls under a category of drugs known as benzodiazepines and works by calming the nerves and the brain.

Alone or as an adjunct, it is used in the treatment of petit mal variant, akinetic, myoclonic seizures, petit mal (absence) seizures which are unresponsive to succimides. It is also used to treat panic disorders with or without agoraphobia.

Clonazepam works like a tranquilizer. It impedes synaptic transmission. The medicine reduces serotonin usage and is able to treat anxiety and seizures. The dosage of Clonazepam will be prescribed by the doctor depending on your condition, how your response has been to the treatment so far, and also your age. When it comes to children, age is a determining factor.

To avoid any kind of complications of side effects in the first place, a lower dosage is suggested for adults. The side effects of this medication vary from one patient to another and it is suggested that you consult with a neurologist before deciding to use this medication.

Also, suddenly stopping the consumption of this medicine can result in withdrawal symptoms such as mood swings, muscle cramps, etc.

May produce somnolence, confusion, ataxia, diminished reflexes, or coma. Treatment for benzodiazepine overdose is supportive. Rarely is mechanical ventilation required.

Flumazenil has been shown to selectively block the binding of benzodiazepines to CNS receptors, resulting in a reversal of benzodiazepine-induced CNS depression, but not respiratory depression.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. While using this medication, do not use alcohol and other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). If medication is used to control seizures, wear identification that you are taking an antiepileptic medication.

    What are the uses of Lonazep 0.25 MG Tablet

    What are the contraindications of Lonazep 0.25 MG Tablet ?

    What are the side effects of Lonazep 0.25 MG Tablet ?

    Key highlights of Lonazep 0.25 MG Tablet

    • How long is the duration of effect?

      The effect of the medicine lasts for six to eight hours in adults. In infants and children, it can last up to twelve hours.

    • What is the onset of action?

      You will see the effects of this medicine within forty minutes of administering it.

    • Are there any pregnancy warnings?

      Pregnant women should consult a doctor before use.

    • Is it habit forming?

      No habit forming tendencies have been reported.

    • Are there any breast-feeding warnings?

      Breastfeeding women should consult a doctor before using this medicine.

    • Is It safe with alcohol?

      This medicine should not be taken with alcohol.

    • Is it safe to drive while on this medicine?

      You should definitely not drive when you are on this medicine.

    • Does this affect liver function?

      This medication has repercussions on the functions of the liver. People with liver problems are usually not prescribed this medication.

    • Does this affect kidney function?

      If you are suffering from kidney-related disorders, it is suggested that you notify your doctor so that the dose is adjusted accordingly. It has been found that lowered kidney functioning leads to the build-up of Clonazepam within the body.

    What are the substitutes for Lonazep 0.25 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Lonazep 0.25 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose, take the tablet any other time as long as its not right before the next dose. Do not take two doses together.

    • Are there any overdose instructions?

      Overdose of this medicine can have terrible effect on both your mind and body. If you have overdosed, contact your doctor without any delay.

    How does this medication work?

    This medication is an anti-convulsant and an anti-epileptic which acts as a tranquilizer. It inhibits the synaptic transmission that occurs in the central nervous system. This also reduces the use of serotonin by neurons and is used to treat seizures and anxiety.

      What are the interactions of Lonazep 0.25 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Additive CNS depression has been reported with benzodiazepines; avoid or limit alcohol
      • Interaction with Medicine

        The drug should not be used in combination with Atenolol and Codeine. Carbamazepine, rifampin, rifabutin may enhance the metabolism of clonazepam and decrease its therapeutic effect; consider using an alternative sedative/hypnotic agent.

        Cimetidine, ciprofloxacin, clarithromycin, clozapine, CNS depressants, diltiazem, disulfiram, digoxin, erythromycin, ethanol, fluconazole, fluoxetine, fluvoxamine, grapefruit juice, isoniazid, itraconazole, ketoconazole, labetalol, levodopa, loxapine, metoprolol, metronidazole, miconazole, nefazodone, omeprazole, phenytoin, rifabutin, rifampin, troleandomycin, verapamil may increase the serum level and/or toxicity of clonazepam; monitor for altered benzodiazepine response.

      • Interaction with Disease

        • Use with caution in elderly or debilitated patients, patients with hepatic disease (including alcoholics), or renal impairment. Use with caution in patients with respiratory disease or impaired gag reflex or ability to protect the airway from secretions (salivation may be increased). Worsening of seizures may occur when added to patients with multiple seizure types. Concurrent use with valproic acid may result in absence status. Monitoring of CBC and liver function tests has been recommended during prolonged therapy.
        • Use caution in patients with depression, particularly if suicidal risk may be present. Use with caution in patients with a history of drug dependence. Benzodiazepines have been associated with dependence and acute withdrawal symptoms, including seizures, on discontinuation or reduction in dose. Acute withdrawal, including seizures, may be precipitated in patients after administration of flumazenil to patients receiving long-term benzodiazepine therapy.
        • Benzodiazepines have been associated with anterograde amnesia. Paradoxical reactions, including hyperactive or aggressive behavior, have been reported with benzodiazepines, particularly in adolescent/pediatric or psychiatric patients. Does not have analgesic, antidepressant, or antipsychotic properties.
      • Interaction with Food

        Information not available.

      FAQs about Lonazep 0.25 MG Tablet

      • Ques : What is Lonazep 0 25 mg tablet?

        Ans : Lonazep 0.25 MG Tablet is mainly used in treating and preventing seizures. It comes under the antiepileptic group of drugs and acts as an anticonvulsant. This medicine is taken to control panic attacks. It contains Clonazepam as an active ingredient. Lonazep 0.25 Tablet works by enhancing the activity of gamma-aminobutyric acid (GABA) neurotransmitter.

      • Ques : What is the use of Lonazep 0 25 mg tablet?

        Ans : Lonazep 0.25 MG Tablet is used for the treatment and prevention from conditions and symptoms of diseases like different types of seizures, panic attacks and linked episodes of anxiety and a certain sleep disorder known as REM Sleep Behaviour Disorder. The patient can inquire a doctor for any other uses of this medicine. The patient should inform the doctor about any ongoing medications and treatment before using Lonazep 0.25 MG Tablet to avoid undesirable effects.

      • Ques : What are the side effects of Lonazep 0 25 mg tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Lonazep 0.25 MG Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include Depression, Sleepiness, Nervousness, Muscle Pain, Twitches In The Tongue And Face, Loss Of Libido and Loss Of Vision Or Blurred Vision.

      • Ques : Can I take Lonazep while taking a dietary supplement?

        Ans : Using Lonazep 0.25 MG Tablet while taking a dietary supplement depends on what kind of dietary supplement it is. Normally absorption of Lonazep is not affected by food and other vitamins. Consult your doctor before you start taking the medication. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use lonazep 0 25 mg tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So, please consult your doctor.

      • Ques : At what frequency do I need to use lonazep 0 25 mg tablet ?

        Ans : This medication is generally used twice or thrice a day, as the time interval upto which this medication has an impact, is around 8 to 10 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

      • Ques : Should I use lonazep 0 25 mg tablet empty stomach, before food or after food?

        Ans : The action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      • Ques : What are the instructions for storage and disposal of lonazep 0 25 mg tablet?

        Ans : This medication contains salts, which are suitable to store at 25 C temperature and keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication, away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      • Ques : Is Lonazep 0.25 MG Tablet a sleeping pill?

        Ans : This medication is not used as a sleeping pill as it might cause difficulty in sleeping.

      • Ques : Can Lonazep 0.25 MG Tablet be taken for the longer-term?

        Ans : You need to take this drug as long as the doctor has advised you. Suddenly stopping it or changing the dose may cause seizures to recur.

      • Ques : On stopping Lonazep 0.25 MG Tablet what kind of withdrawal symptoms occur?

        Ans : The common symptoms that will be seen after stopping this drug are difficulty in sleeping, changes in mood, and increased sweating. In some cases, it might also result in muscle pain, headache, shaking (tremor) or feeling restless, feeling very anxious, tense, etc.

      • Ques : How can I look for early symptoms of suicidal thoughts and actions?

        Ans : You should pay attention to changes that take place in your body, especially sudden changes in mood, behaviors, thoughts, or feelings. You must consult the doctor on a regular basis.

      • Ques : Does Lonazep 0.25 MG Tablet cause weight gain?

        Ans : Yes, in some cases it might cause weight gain and weight loss. It is advised to consult the doctor before consuming it.

      • Ques : Can Lonazep 0.25 MG Tablet affect my memory?

        Ans : No, it does not affect memory. The patient may complain of partial to recall the recent past.

      • Ques : Can Lonazep 0.25 MG Tablet be harmful if more than the recommended doses are used?

        Ans : Overdose can cause sleepiness, change in speech, confusion, abnormalities in eye movement, etc.

      • Ques : Can I take Lonazep 0.25 MG Tablet and zolpidem together?

        Ans : The combination of Lonazep 0.25 MG Tablet and zolpidem should be avoided as it may have increased the chances of side effects.

      • Ques : Can Lonazep 0.25 MG Tablet and quetiapine be taken together?

        Ans : If both these medications are used together the side effects may increase. The side effects might include drowsiness, confusion, weakness, breathing trouble, etc.

      References

      • Clonazepam (Rivotril): Uses, Side Effects,Mechanism & Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 26 April 2019]. Available from:

        https://www.drugsbanks.com/clonazepam-rivotril/

      • Clonazepam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/clonazepam

      • CLONAZEPAM- clonazepam tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2008 [Cited 26 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acbce0e8-5098-4785-943b-8bdb5ff17fab

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Anil MehtaMBBS, DNB (General Medicine)General Physician
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