Losar-H Tablet

This is a combination medication which has Losartan and Hydrochlorothiazide as active ingredients. It belongs to the angiotensin II receptor antagonists group of drugs. This prevents the blood vessels in your body from narrowing, thus lowering your blood pressure and improving the blood circulation. It can lower the possible risk of a stroke in people suffering from any heart condition. Apart from that, it can also slow down kidney damage among people with type 2 diabetes.

There are three main reasons for its usage. Firstly, it is used for the treatment of high blood pressure. The second usage is for reducing the risk of stroke in people, who already have high blood pressure as well as left ventricular hypertrophy (LVH). Lastly, this medication is used for treating diabetic nephropathy, a kidney disease caused due to diabetes.

There are some common side effects of this medication that are generally mild and go away in a few days. They include:

• Stuffy nose
• Back pain
• Diarrhea
• Fatigue and dizziness
• Pain in the chest
• High/low blood pressure

• Hypertension

• Diabetic Nephropathy

• Congestive Heart Failure

• Allergy

• Aliskiren

• Anuria

• Severe Liver Impairment

• Stomach Pain

• Chills

• Difficulty Or Painful Urination

• Fast Heartbeat

• Chest Tightness

• Dizziness

• Weakness In Arms, Hands, Legs Or Feets

• Nasal Congestion

• How long is the duration of effect?

  This medication is excreted largely in faeces and the effect lasts for a duration of approximately 24 hours.

• What is the onset of action?

  The peak effect of this medication can be observed in 1 to 1.5 hours.

• Are there any pregnancy warnings?

  This medication is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  This medication is not recommended for women who are breastfeeding.

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

This medication displaces angiotensin II with very high affinity from its binding site at the AT1 receptor subtype, which is responsible for the known actions of angiotensin II. Hydrochlorothiazide is a diuretic which inhibits a sodium-chloride symporter SLC12A3 in the distal convoluted tubule to inhibit water reabsorption in the nephron. The symporter reabsorbs sodium and creates an osmotic gradient for water to be reabsorbed, inhibition of which prevents water reabsorption.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Consumption of alcohol with this medication will lower the blood pressure and can cause dizziness, headache, changes in heart rate. Avoid driving or operating heavy machinery if you have these symptoms.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Aliskiren

  Use of these medicines is not recommended especially in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min. You experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.

  Captopril

  Use of these medicines is not recommended as it may increase the risk of kidney impairment and low blood pressure. You may experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.

  Dexamethasone

  The desired effect of this medication will not obtain if these medicines are taken together. This interaction is more likely to happen if dexamethasone is taken for more than 1 week. Inform the doctor if you have a sudden weight gain, swelling of hands and feet. If coadministration is needed then appropriate dose adjustments are to be made under the doctor's supervision. Regular monitoring of blood pressure and kidney function tests are to be performed.

  Diclofenac

  The desired effect of this medication will not obtain if these medicines are taken together. The risk of kidney impairment will increase if these medicines are taken together especially in the elderly population or having pre-existing kidney disease. Inform the doctor if you have an increased or decreased urination and unexplained weight gain or weight loss. Regular monitoring of blood pressure and kidney function tests are to be performed.

  Insulin

  The effect of insulin will increase if these medicines are taken together. You may experience dizziness, headache, sweating if these medicines are taken together. Regular monitoring of blood glucose levels is needed. Suitable dose adjustments or an alternate medicine should be considered under the doctor's supervision.

• Interaction with Disease

  Congestive Heart Failure (Chf)

  This medication is used with caution in patients with congestive heart failure especially in volume or sodium depletion. Transient hypotension is also not a contraindication to further treatment with AR antagonists since therapy can usually be reinstated without difficulty after blood pressure stabilizes.

• Interaction with Food

  Food

  Information not available.

• Ques : What is losar h tablet?

  Ans : This medication belongs to the angiotensin II receptor antagonists group of drugs. It prevents the blood vessels in your body from narrowing, thus lowering your blood pressure and improving the blood circulation. This medication contains Losartan and Hydrochlorothiazide as working ingredients.

• Ques : What are the uses of losar h tablet?

  Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like high blood pressure condition in patients who are suffering from the state of uncontrolled blood pressure on losartan or hydrochlorothiazide.

• Ques : What are the Side Effects of losar h tablet?

  Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include back pain, chest pain, cough, decrease in the level of hemoglobin, diarrhea, dizziness, fatigue, headache, high blood potassium levels, etc.

• Ques : What are the instructions for storage and disposal losar h tablet?

  Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Losar-H.

• Ques : How long do I need to use Losar-H Tablet before I see improvement of my conditions?

  Ans : This medication takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Losar-H Tablet?

  Ans : Contraindication to losar-H. In addition, this medication should not be used if you have the following conditions such as sun-allergic reaction, hives, fever, respiratory distress, excess fluid in the lungs, etc.

• Ques : Is Losar-H Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Losar-H Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as back pain, chest pain, cough, diarrhea, dizziness, fast or irregular heartbeat, fatigue, headache, high blood potassium levels, etc.