Mac RD Capsule

Mac RD Capsule is indicated for treating GERD (Gastro-esophageal reflux disease), which not responds to Rabeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Mac RD is a combination of Domperidone and Rabeprazole. The active ingredients, Domperidone and Rabeprazole fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

Mac RD Capsule is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

Mac RD medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Mac RD Capsule if you have the following conditions:

• An allergy to Mac RD Capsule or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Stomach Pain

• Headache

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medication lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medication can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  Mac RD Capsule is generally not recommended for pregnant women and should only be used if clearly needed under the supervision of a doctor.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Mac RD Capsule is not recommended for women who are breastfeeding as it affects the development of infant's joints. Use only if clearly needed under the supervision of a doctor.

• Is It safe with alcohol?

  Consult your doctor before consuming alcohol.

• Is it safe to drive while on this medicine?

  Side effects include dry mouth, dizziness, diarrhea etc.

• Does this affect kidney function?

  Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

• Does this affect liver function?

  Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

Below is the list of medicines, which have the same composition, strength and form as Mac RD Capsule , and hence can be used as its substitute.

• T Rab DSR Tablet

  Tetramed Biotek Pvt Ltd

• Raptac-Dsr Capsule

  Rapross Pharmaceuticals Pvt Ltd

• Pepzera D 30 Mg/20 Mg Capsule

  Pulse Pharmaceuticals

• Cidrid 30 Mg/20 Mg Capsule

  Profic Organic Ltd

• Rabex Capsule

  Xellence Laboratories

• Robilink Dsr Capsule

  Lincoln Pharmaceuticals Ltd

• Rolmizac D 30Mg/20Mg Capsule

  Arinna Lifescience Pvt Ltd

• Rabekind-Dsr Capsule

  Mankind Pharma Ltd

• RABRAL D 30MG/20MG TABLET

  Life Care Pharmaceuticals Pvt Ltd

• Rabera-DSR Capsule

  Jenburkt Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

Mac RD Capsule attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid consuming a large amount of alcohol acidity can increase and might cause acid reflux in the food pipe which would cause heartburn.

• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  The medication should not be used in patient suffering from kidney or liver disease.

• Ques : What is Mac rd capsule?

  Ans : Mac RD has Domperidone and Rabeprazole Sodium as active elements present. It perform its action by obstructing the dopamine receptors, reducing the amount of acid made by the stomach.

• Ques : What are the uses of Mac rd capsule?

  Ans : Mac RD Capsule is used for the treatment and prevention from conditions such as treatment for intractable nausea and vomiting, gastroesophageal reflux disease, and duodenal ulcer.

• Ques : What are the Side Effects of Mac RD capsule?

  Ans : Mac RD has some commonly reported side effects such as Loss of interest in sex, headache, somnolence, akathisia, diarrhea, rash, pruritus, breast enlargement, breast tenderness, galactorrhoea, amenorrhea, etc.

• Ques : What are the instructions for storage and disposal Mac rd capsule?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Mac RD Capsule before I see improvement of my conditions?

  Ans : This medication takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Mac RD Capsule?

  Ans : Contraindication to Mac RD. In addition, this medication should not be used if you have the following conditions such as hypersensitivity, hypersensitivity to domperidone, moderate or severe hepatic impairment, etc.

• Ques : Is Mac RD Capsule safe to use when pregnant?

  Ans : Mac RD Capsule is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Mac RD Capsule be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as headache, somnolence, akathisia, diarrhea, rash, pruritus, breast enlargement, breast tenderness, etc.

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184

• Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

• Rabeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01129