Macprox Dp 250 Tablet

Macprox Dp 250 Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprized of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

• Migraine Headache

• Migraine Prophylaxis

• Nausea Or Vomiting

• Tumor Of Pituitary Gland

• Allergy

• Asthma

• Gastrointestinal Discomfort

• Severe Liver Impairment

• Dry Mouth

• Flu-Like Symptoms

• Indigestion

• Is It safe with alcohol?

  Taking this medication with alcohol can increase the risk of stomach bleeding caused by naproxen.

• Are there any pregnancy warnings?

  The medication may be unsafe to use during pregnancy.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Do not drive, operate machinery.

• Does this affect kidney function?

  This medication should not be given in renal failure. Caution should be used in patients with severe renal impairment.

• Does this affect liver function?

  There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.

Below is the list of medicines, which have the same composition, strength and form as Macprox Dp 250 Tablet , and hence can be used as its substitute.

• Minado Tablet

  Tas Med India Pvt Ltd

• Napra D 250mg Tablet

  Intas Pharmaceuticals Ltd

• Comig 250 Tablet

  Seagull Labs (I) Pvt Ltd

• Pacinac NP 250mg/10mg Tablet

  Gentech Healthcare Pvt Ltd

• Naprodom 250Mg Tablet

  Crescent Therapeutics Ltd

• Xenadom 250 Mg/10 Mg Tablet

  Icon Life Sciences

• Are there any missed dose instructions?

  It is suggested to take the missed dose as soon as you remember.

• Are there any overdose instructions?

  Doctor consultation is suggested if an overdose is suspected.

This medication is a combination of Naproxen and Domperidone. This medicine is prescribed for the treatment of migraine attacks. As both the drugs belong to two different classes, namely, NSAIDs (Non-Steroidal Anti Inflammatory Drug) and Dopamine antagonist, respectively, thus it works via dual mechanism.

Firstly it inhibits prostaglandin synthesis by non selectively impeding the COX -1 and COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. Secondly, it gets attached to the dopaminergic receptors without causing any release of the chemical dopamine. This, in turn, eases gastric emptying and abate small bowel transit time.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Limit the consumption of alcohol while taking this medication.

• Interaction with Medicine

  Medicine

  Do not take this medication in combination with Cisapride, Erythromycin, Ketoconazole, Ramipril, Tramadol, Warfarin, Ketorolac, Bromocriptine and Prednisolone.

• Interaction with Disease

  Disease

  This medication should not be used if you suffer from Asthma, Kidney Disease, Heart Disease, Liver Disease and Intestinal Disorders.

• Ques : What is Macprox Dp 250 Tablet used for?

  Ans : This medication is used to treat migraine, its prophylaxis and nausea and vomiting associated with it. It contains domperidone and naproxen as active ingredients. Do not chew or break this medicine, it has to be swallowed as a whole and can be taken with or without food at a fixed time.

• Ques : What are the side effects of Macprox Dp 250 Tablet?

  Ans : This medication has several side effects that can appear because of it’s ingredients which are domperidone and naproxen.

  Some of the side effects are mentioned below;

  • Drowsiness
  • Headache
  • Depression
  • Itching
  • Inability of concentration
  • Swelling of eyes and lips

• Ques : How does the medicine work?

  Ans : This medication consist domperidone and naproxen in which domperidone helps in getting rid from undiagestest food and reducing the risk of an upset stomach, heartburn and throwing up, while naproxen works reducing hormones that cause pain, swelling and fever. this medicine can be used to treat migraine, migraine prophylaxis and nausea and vomiting symptoms associated with it

• Ques : Is Macprox Dp 250 Tablet safe during pregnancy?

  Ans : Kindly consult with a doctor or specialist for a recommendation on a particular case.

• Naproxen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/naproxen

• Naproxen- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00788

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184