Metacin Suppository

Metacin Suppository is used as a Pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

1. You are allergic to this medicine.
2. You are suffering from a serious liver disorder.
3. You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

There are several drugs that may interact with Metacin Suppository. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over the counter drugs and herbal products.

For adults Metacin Suppository the general dose for fever and pain is 325-650 mg tablets once in every 4 to 6 hours or 1000mg tablets once in every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Metacin Suppository toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based upon laboratory analysis suggesting high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult prescriber for anti-inflammatory, if needed.

Take exactly as directed (do not increase dose or frequency); most adverse effects are related to excessive use. Take with food or milk. While using this medication, avoid alcohol and other prescription or OTC medications that contain acetaminophen or Metacin Suppository.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Fever

• Headache

• Muscle Pain

• Menstrual Cramps

• Arthritis

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Allergy

• Analgesic Nephropathy (Kidney Disease)

• Liver Disease

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Nausea Or Vomiting

• Allergic Skin Reaction

• Gastric / Mouth Ulcer

• Anemia

• Fatigue

• Stevens-Johnson Syndrome (Sjs)

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• How long is the duration of effect?

  The effect lasts for an average of 4-6 hours.

• What is the onset of action?

  The effect of this drug can be observed within an hour of administration.

• Are there any pregnancy warnings?

  It should be used only when necessary after consulting a doctor for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine.

• Does this affect liver function?

  Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

• Does this affect kidney function?

  Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:

  • Clcr 10-50 mL/minute: Administer every 6 hours.
  • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
  • Hemodialysis: Moderately dialyzable (20% to 50%).
  Consult your doctor before taking this medication.

• Is It safe with alcohol?

  Excessive intake of alcohol may increase the risk of acetaminophen-induced hepatotoxicity; avoid or limit alcohol intake.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any missed dose instructions?

  The missed dose should be taken as soon as possible.

• Are there any overdose instructions?

  An overdosage could cause harmful effects on the body.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

The drug is a pain relief medication that selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  You should avoid consuming alcohol while taking this medicine. Symptoms like fever, chills, rashes, joint pain and swelling, excessive weakness, nausea should be immediately reported to the doctor.

• Interaction with Lab Test

  5-HIAA Urine Test

  You may get a false-positive result for this test if you take Metacin Suppository.

• Interaction with Medicine

  One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced

• Interaction with Food

  May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates

• Interaction with Disease

  Patients suffering from liver disease should use some other safer alternative.

• Ques : What is Metacin Suppository?

  Ans : This is a medication that performs its action by obstructing the release of pain and fever chemical messengers.

• Ques : What are the uses of Metacin Suppository?

  Ans : This medicine is used for the treatment and prevention of conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.

• Ques : What are the Side Effects of Metacin Suppository?

  Ans : Allergic reaction, gastric ulcers, fatigue, anaemia, nausea and vomiting are possible side effects.

• Ques : What are the instructions for storage and disposal Metacin Suppository?

  Ans : This medicine should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Metacin Suppository empty stomach, before food or after food?

  Ans : If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

• Ques : How long do I need to use Metacin Suppository before I see improvement of my conditions?

  Ans : This medication should be consumed, until the complete eradication of the disease. It is advised to use, till the time directed by your doctor.

• Ques : Is there any food or drink I need to avoid?

  Ans : You can follow your normal diet under the usage of this medication.

• Ques : Will Metacin Suppository be more effective if taken in more than the recommended dose?

  Ans : There is no need to take this medication more than its recommended doses.

• Ques : Can I take other medications along with Metacin Suppository?

  Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. Metacin Suppository contains many combination of medicines. If you use certain products together you may accidentally use too much of Metacin Suppository.

• Ques : Can I take Metacin Suppository with antibiotics?

  Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

• Ques : Is Metacin Suppository an NSAID drug?

  Ans : No, this medication is not classified as an NSAID (Nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.

• Dolo 650 mg (Paracetamol): Uses, Side Effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 3 December 2021]. Available from:

  https://www.drugsbanks.com/dolo-650-mg/

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 3 December 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

• Anadin Paracetamol Tablets- EMC [Internet]. www.medicines.org.uk. 2016 [Cited 3 December 2021]. Available from:

  https://www.medicines.org.uk/emc/product/11899/smpc