Minado Tablet

Minado Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprized of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.

On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.

To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.

Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.

To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.

• Migraine Headache

• Prevention Of Migraine Attacks

• Allergy

• Peptic Ulcer

• Hypersensitivity

• Dry Mouth

• Indigestion

• Flu-Like Symptoms

• Is It safe with alcohol?

  Taking this medication with alcohol can increase the risk of stomach bleeding.

• Are there any pregnancy warnings?

  This medication is unsafe to use during pregnancy. Please consult your doctor.

• Are there any breast-feeding warnings?

  Breastfeeding women must consult doctor before using this medication.

• Is it safe to drive while on this medicine?

  Do not drive, operate machinery.

• Does this affect kidney function?

  This medication should not be given in renal failure. Caution should be used in patients with severe renal impairment.

• Does this affect liver function?

  There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.

Below is the list of medicines, which have the same composition, strength and form as Minado Tablet , and hence can be used as its substitute.

• Macprox Dp 250 Tablet

  Macleods Pharmaceuticals Pvt Ltd

• Napra D 250mg Tablet

  Intas Pharmaceuticals Ltd

• Comig 250 Tablet

  Seagull Labs (I) Pvt Ltd

• Pacinac NP 250mg/10mg Tablet

  Gentech Healthcare Pvt Ltd

• Naprodom 250Mg Tablet

  Crescent Therapeutics Ltd

• Xenadom 250 Mg/10 Mg Tablet

  Icon Life Sciences

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

Minado tablet is composed of Naproxen and Domperidone. Naproxen is NSAID (Non Steroidal Anti Inflammatory Drug) that inhibit prostaglandin synthesis by non selectively impeding the COX -1 And COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. Domperidone attaches to the dopaminergic receptors without causing any release of the chemical dopamine. This in turn, facilitates gastric emptying and decreases small bowel transit time.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Medicine

  This medication interacts with Amiodarone, Amprenavir, Antacids, Aprepitant, Atazanavir, Atropine, Bisoprolol, Ciprofloxacin.

• Interaction with Disease

  Disease

  Do not use this medication if you suffer from Kidney Disease, Heart Disease, Asthma and others.

• Ques : What is Minado Tablet?

  Ans : Minado has Domperidone and Naproxen as active elements present in it. This medicine performs its action by obstructing the dopamine receptors, obstructing the effect of an enzyme called cyclooxygenase resulting in reduced production of prostaglandins.

• Ques : What are the uses of Minado Tablet?

  Ans : Minado is used for the treatment and prevention from conditions such as Acute migraine attacks and Treatment for intractable nausea and vomiting.

• Ques : What are the Side Effects of Minado Tablet?

  Ans : Side effects include Heart failure, Headache, Somnolence, Akathisia, Diarrhea, Rash, Pruritus, Breast enlargement, Breast tenderness, Galactorrhoea, Amenorrhea, Breast pain, Menstruation irregular, Lactation disorder, Asthenia, Lightheadedness, Liver dysfunction, Visual disturbances, Inability to concentrate, Kidney failure, Vertigo, Indigestion, Nausea, Thirst, Breathlessness, Skin rash, Abdominal pain, Abnormal blood counts, and Vomiting.

• Ques : What are the instructions for storage and disposal Minado Tablet?

  Ans : Minado should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

• Naproxen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/naproxen

• Naproxen- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00788

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/domperidone

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184