Nexito Forte Tablet

Nexito Forte Tablet is used to treat and prevent generalized anxiety disorder and depression. This medicine is a combination of an anti-epileptic and an anti-convulsant in combination with an antidepressant. This medicine is administered to control panic attacks.

Belonging to a cluster of drugs called benzodiazepines. It works by inducing a calming effect on your nerves and brain. The most common side effects include

• drowsiness
• dizziness
• fatigue
• loss of focus
• increased secretion of saliva in the mouth.

Let your doctor know if you have been feeling depressed for no particular reason. If you notice any change in the way you behave with people around you. Other side effects include rash, itching, sore throat and fever.

This medication can increase suicidal thoughts and behaviours especially amongst teenagers, children, and young adults if taken in excess amounts. Hence, this drug should only be taken under a doctor’s prescription.

This medication is normally prescribed to be taken once a day. The usual dose is 10-20 mg for adults as well as children. It is not suitable for everyone as it might cause harmful effects on people suffering from certain conditions.

If you are suffering from irregular heartbeats or are allergic to certain ingredients present in the medicine, it is advisable to consult with the doctor first. Also, this medication might have a harmful effect on a pregnant woman. Consult with the doctor if you have a history of liver disease or kidney disease.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. While using this medication, do not use alcohol and other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.

• Anxiety Disorder

• Liver Disease

• Glaucoma

• Allergy

• Delayed Ejaculation

• Confusion

• Vomiting

• Memory Impairment

• Drowsiness

• Tiredness

• Diarrhoea

• Uncoordinated Body Movements

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 6 to 8 hours in adults. This duration increases to 12 hours in infants and children.

• What is the onset of action?

  The effect of this medicine can be observed within 30 to 40 minutes of administration.

• Are there any pregnancy warnings?

  This medicine is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

• Is it habit forming?

  Especially in some cases, If the usage of medicine is for an extended period of time then this kind of Habit forming tendencies should be reported. In such cases, gradual withdrawal of drug is initiated by decreasing dose over a period of time.

• Are there any breast-feeding warnings?

  The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

• Is It safe with alcohol?

  It is unsafe to consume alcohol with this medicine. Kindly consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine may cause side effects that affects the consciousness of the patient. Thus driving must be avoided while taking this medicine.

• Does this affect kidney function?

  This medicine is probably safe to be used in patients with kidney disease. Availability of limited data suggests that adjustment of dose might not be needed. Kindly consult your doctor before this medicine.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Nexito Forte Tablet , and hence can be used as its substitute.

• Panicalm 0.5 Mg/10 Mg Tablet

  RPG Life Sciences Ltd

• DESTRES EC TABLET

  Midas Healthcare Ltd

• Esciram Cl 0.5 Mg/10 Mg Tablet

  Ceras Pharmaceutical

• Restovis D Tablet

  Avis Lifecare Pvt Ltd

• Atpram-C 0.5 Mg/10 Mg Tablet

  Octane Biotech Pvt Ltd

• S-Citapad Plus Tablet

  Tripada Healthcare Pvt Ltd

• Desilam Plus 0.5 Mg/10 Mg Tablet

  MSN Laboratories

• Ecit-Plus Tablet

  Talent Healthcare

• Caspa Plus Tablet

  Thrift Pharmaceuticals

• Citajoy C 0.5 mg/10 mg Tablet

  Wings Biotech Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. It is recommended to skip your missed dose if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  In case of overdose, consult your doctor.

Nexito tablet is an anticonvulsant and an ant-epileptic which acts as a tranquilizer. It inhibits the synaptic transmission that occurs in the central nervous system. This also reduces the use of serotonin by neurons and is used to treat seizures and anxiety. Acts as a selective inhibitor of serotonin (5-HT) re-uptake with high affinity for the primary binding site. Binds to an allosteric site on the serotonin transporter, with a 1000 fold lower affinity.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Additive CNS depression has been reported with benzodiazepines; avoid or limit alcohol

• Interaction with Medicine

  • The combined use of Nexito Forte Tablet and valproic acid has been associated with absence seizures.
  • Carbamazepine, rifampin, rifabutin may enhance the metabolism of Nexito Forte Tablet and decrease its therapeutic effect; consider using an alternative sedative/hypnotic agent.
  • Cimetidine, ciprofloxacin, clarithromycin, clozapine, CNS depressants, diltiazem, disulfiram, digoxin, erythromycin, ethanol, fluconazole, fluoxetine, fluvoxamine, grapefruit juice, isoniazid, itraconazole, ketoconazole, labetalol, levodopa, loxapine, metoprolol, metronidazole, miconazole, nefazodone, omeprazole, phenytoin, rifabutin, rifampin, troleandomycin, verapamil may increase the serum level and/or toxicity of clonazepam; monitor for altered benzodiazepine response.

• Interaction with Disease

  This medication interacts with the following disease Seizure disorders, Closed-Angle Glaucoma, and Respiratory disorders.

• Ques : What is Nexito Forte Tablet?

  Ans : Nexito tablet is a medication which has Clonazepam and Escitalopram as active elements present in it. This medicine performs its action by increasing the activity of serotonin in the brain, enhancing the activity of gamma-aminobutyric acid (GABA) neurotransmitter.

• Ques : What are the uses of Nexito Forte Tablet?

  Ans : This is a medication, which is used for the treatment and prevention from conditions such as Anxiety, Major depressive disorder, Treatment of panic disorder, Depression, Panic disorder, and Treatment of seizure disorder, Mental disorder, Epilepsy, and Depressive disorder, etc.

• Ques : What are the Side Effects of Nexito Forte Tablet?

  Ans : Nexito is a medication which has some commonly reported side effects such as Ejaculation disorder, Abnormal eye movements, Drowsiness, Impotence in males, Constipation, Nausea, Insomnia, Slurred speech, Depressive mood, Muscle weakness, etc.

• Ques : What are the instructions for storage and disposal Nexito Forte Tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Nexito Forte Tablet before I see improvement of my conditions?

  Ans : This is a medicine which takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Nexito Forte Tablet?

  Ans : Contraindication to Nexito forte tablet. In addition, this medication should not be used if you have the following conditions such as Acute narrow-angle glaucoma, Concomitant use with monoamine oxidase inhibitors, etc.

• Ques : Is Nexito Forte Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

• Ques : Will Nexito Forte Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of Nexito can lead to increased chances of side effects such as Ejaculation disorder, Abnormal eye movements, Drowsiness, Impotence in males, etc.

• Escitalopram- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 29 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/escitalopram

• Escitalopram- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB01175

• Clonazepam (Rivotril): Uses, Side Effects,Mechanism & Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 26 April 2019]. Available from:

  https://www.drugsbanks.com/clonazepam-rivotril/

• Clonazepam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/clonazepam