Nexpro Rd 20 Capsule Sr

Nexpro RD Capsule is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Esomeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Nexpro Rd 20 Capsule Sr is a combination of Domperidone and Esomeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

Nexpro RD is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

Nexpro RD medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Nexpro Rd 20 Capsule Sr if you have the following conditions:

• An allergy to Nexpro Rd 20 Capsule Sr or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medication lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medication can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  Till the first trimester of pregnancy, the oral and topical forms of this medicine are safe for consumption. It, however, should only be used when extremely needed. The medication should not be consumed in oral form during pregnancy. Doctor consultation to evaluate potential benefits and risks before consumption is mandatory.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Nexpro RD Capsule is not recommended for use by breastfeeding mothers as there is a risk of side effects on the infant. You are advised to consult your doctors and consider the potential benefit and risks before consuming this medication.

Below is the list of medicines, which have the same composition, strength and form as Nexpro Rd 20 Capsule Sr , and hence can be used as its substitute.

• Sompraz D 20 Capsule Sr

  Sun Pharmaceutical Industries Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

Nexpro RD Capsule attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  Nexpro RD Capsule interacts with Kidney disease, Liver disease and Intestinal disorders.

• Ques : What is Nexpro Rd 20 Capsule Sr?

  Ans : This medication has Domperidone and Esomeprazole as active elements present. It performs its action by obstructing the dopamine receptors, reducing the amount of acid produced in the stomach.

• Ques : What are the uses of Nexpro Rd 20 Capsule Sr?

  Ans : Nexpro RD Capsule is used for the treatment and prevention from conditions such as gastroesophageal reflux disease, gastric ulcers, peptic ulcer, treatment for symptoms associated with idiopathic or diabetic gastroparesis, etc.

• Ques : What are the Side Effects of Nexpro Rd 20 Capsule Sr?

  Ans : This medication has some commonly reported side effects such as diarrhea, headache, somnolence, akathisia, rash, pruritus, breast enlargement, breast tenderness, galactorrhoea, amenorrhea, breast pain, etc.

• Ques : What are the instructions for storage and disposal Nexpro Rd 20 Capsule Sr?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Nexpro Rd 20 Capsule Sr before I see improvement of my conditions?

  Ans : Nexpro RD Capsule takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Nexpro Rd 20 Capsule Sr?

  Ans : Contraindication to met neurobion. In addition, this medication should not be used if you have the following conditions such as Hypersensitivity to domperidone, Moderate or severe hepatic impairment, Patients with significant electrolyte disturbances, etc.

• Ques : Is Nexpro Rd 20 Capsule Sr safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicating.

• Ques : Will Nexpro Rd 20 Capsule Sr be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as diarrhea, headache, somnolence, akathisia, rash, pruritus, breast enlargement, breast tenderness, etc.

• Esomeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/esomeprazole

• Esomeprazole- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00736

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184