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Overview

Notence 1 MG Tablet

Manufacturer :  Crescent Formulations Pvt. Ltd
Medicine Composition :  Alprazolam
Prescription vs OTC : Prescription by Doctor not required

About Notence 1 MG Tablet

Notence 1 MG Tablet is an effective drug prescribed to patients who have panic disorders and anxiety disorders as a result of depression. The drug controls the levels of certain unbalanced chemicals released by the brain in patients who suffer from depression. Notence 1 MG Tablet is a part of a group of medicines which go by the name of benzodiazepine. This class of drugs work in a way through which they calm the brain and the central nervous system, preventing panic attacks.

The drug is meant for oral consumption and should not be chewed or swallowed whole. Allow the tablet to dissolve when you place it in your mouth before gulping it down. In case you are taking the liquid form of Notence 1 MG Tablet, measure it properly and only take the dosage that has been prescribed. This drug can become addictive, thus it should be kept away from individuals who have a history of drug addiction.

Before you start the drug be sure to research some general information about it. For instance, the drug is not meant for patients who suffer from problems like glaucoma and allergies. Inform your doctor if you have health issues like epileptic seizures, asthma, suffer from depression and suicidal thoughts, addiction to alcohol or drugs or take narcotic medication, to ensure if Notence 1 MG Tablet is safe for consumption. Notence 1 MG Tablet can result in birth defects. Therefore it cannot be taken by pregnant women. Traces of the drug has been found in breast milk too and can have a negative impact on the infant. Thus, nursing mothers are also advised not to take Notence 1 MG Tablet.

Some side effects of the drug include tiredness, feeling sleepy, memory issues, and developing anxiousness. Experiencing withdrawal symptoms is also a common side effect of Notence 1 MG Tablet .

Misuse of Notence 1 MG Tablet can result in over dosage and even death in extreme cases.

    What are the uses of Notence 1 MG Tablet

    • Anxiety

      Notence 1 MG Tablet is used in the treatment of anxiety disorders. Uneasiness, difficulty in sleeping, sweating of hands and feet are some of the symptoms of anxiety disorder.

    • Panic Disorder

      Notence 1 MG Tablet is used in the treatment of the panic disorder. Sweating, breathing problem, weakness and numbness in hands are some of the symptoms of panic disorder.

    What are the contraindications of Notence 1 MG Tablet ?

    • Allergy

      Avoid taking this medicine if you have a known allergy to Notence 1 MG Tablet or other benzodiazepines.

    • Azole antifungal agents

      Avoid taking this medicine If you are using azole antifungal agents like Ketoconazole and Itraconazole. These medicines will increase the concentration of Notence 1 MG Tablet by increasing its availability in the body.

    What are the side effects of Notence 1 MG Tablet ?

    • Changes In Pattern Of Speech

    • Unsteadiness

    • Loss Of Coordination

    • Drowsiness

    • Blurred Vision

    • Abdominal Pain

    • Difficulty Or Painful Urination

    • Headache

    • Chest Pain

    • Sleeplessness

    • Irregular Menstrual Periods

    • Decreased Appetite

    • Weight Loss

    • Double Vision

    • Sudden Sweating

    • Acid Or Sour Stomach

    • Heartburn

    Key highlights of Notence 1 MG Tablet

    • How long is the duration of effect?

      This medicine is excreted in urine and the effect lasts for a duration of 44 hours for an immediate release tablet and 52 hours for an extended release tablet / disintegrating tablet.

    • What is the onset of action?

      The peak effect can be observed in 1 to 2 hours for an immediate release tablet, 1.5 to 2 hours for a disintegrating tablet and 9 hours for an extended release tablet.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women. Use only if clearly required under the supervision of the doctor.

    • Is it habit forming?

      Habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through human breast milk. It is not recommended for breastfeeding women.

    What are the substitutes for Notence 1 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Notence 1 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Notence 1 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    Notence 1 MG Tablet, like other benzodiazepines, has a high affinity for the benzodiazepine binding site in the brain. It facilitates the inhibitory neurotransmitter action of gamma-aminobutyric acid, which mediates both pre- and post-synaptic inhibition in the central nervous system (CNS)

      What are the interactions of Notence 1 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Acute alcohol intoxication

        Consumption of alcohol with this medicine is not recommended as it increases the risk of depression and breathlessness.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Cetirizine

        Use of Notence 1 MG Tablet with cetirizine or levocetirizine should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Metoclopramide

        Use of Notence 1 MG Tablet with metoclopramide should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Opioids

        Opioids like morphine, codeine, tramadol, hydrocodone or any cough preparations containing these medicines should be avoided when you are on Notence 1 MG Tablet or other benzodiazepines. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

        Azole antifungal agents

        Azole antifungal agents like ketoconazole and itraconazole should be avoided when you are Notence 1 MG Tablet due to the risk of increased concentrations of the medicine in the body which may cause increased sedation and changes in ECG. Inform the doctor if you are receiving these medicines when you are prescribed with Notence 1 MG Tablet. If coadministration is needed then alternative medicines like lorazepam and oxazepam could be considered.

        Antihypertensives

        You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
      • Interaction with Disease

        Glaucoma

        Notence 1 MG Tablet is known to increase the fluid pressure inside the eye. It is contraindicated in acute narrow-angle glaucoma which is an eye disorder.

        Seizure Disorders

        The sudden stop of Notence 1 MG Tablet may cause withdrawal effects and can precipitate seizures. The dose should be reduced gradually. Do not stop taking this medicine without consulting the doctor.
      • Interaction with Food

        Grape fruit juice

        Grapefruit juice should be consumed with Notence 1 MG Tablet. Alternatively, you can consume orange juice which does not affect the medicine.

      FAQs about Notence 1 MG Tablet

      • Ques : What is Notence 1 MG Tablet?

        Ans : Notence 1 mg tablet is a medication which has Alprazolam as an active element present in it. This medicine performs its action by binding at several sites within the brain and affecting the chemical action to produce a depressive effect on brain activity. It also obstructs the abnormal activity of nerve cells in the brain. Notence 1 mg tablet is used to treat conditions such as Anxiety or aggressive behaviour, uneasiness, breathing problems and Panic disorder.

      • Ques : What are the uses of Notence 1 MG Tablet?

        Ans : Notence 1 mg tablet is a medication, which is used for the treatment and prevention from conditions such as Anxiety and Panic disorder. This medication is also used treat conditions such as Anxiety or aggressive behaviour, uneasiness, breathing problems, weakness and numbness. It also obstructs the abnormal activity of nerve cells in the brain. The patient should inform the doctor about any ongoing medications and treatment before using Notence 1 mg tablet to avoid undesirable effects.

      • Ques : What are the Side Effects of Notence 1 MG Tablet?

        Ans : Notence 1 mg tablet is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Notence 1 mg tablet which are painful urination, Loss of coordination, Drowsiness, Blurred vision, Abdominal pain, Headache, Chest pain, Sleeplessness, Irregular menstrual periods, Decreased appetite, Weight loss, Double vision, Sudden sweating, Acid or sour stomach, and Heartburn. It is a list of possible side-effects which may occur due to the constituting ingredients of Notence 1 mg tablet.

      • Ques : What are the instructions for storage and disposal Notence 1 MG Tablet?

        Ans : Notence 1 mg tablet should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication. It is important to dispose expired and unused medications properly to avoid health problems.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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