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Overview

Numbex Cream

Manufacturer :  Salve Pharmaceuticals Pvt Ltd
Medicine Composition :  Prilocaine, Lidocaine
Prescription vs OTC : Prescription by Doctor required

About Numbex Cream

Numbex Cream, a local anesthetic drug of the amino amide type, relieves pain of normal intact skin and numbs skin to pain from injections and other medical procedures. It works by blocking nerves from transmitting painful impulses to the brain. In its injectable form, it is used in dentistry. It is also often used in combination with lidocaine as a topical preparation for dermal anesthesia, for treatment of conditions like paresthesia. It is also commonly used for intravenous regional anaesthesia due to its low cardiac toxicity.

Make sure you tell your doctor if you have G6PD deficiency, a history of heart disease, heart rhythm problems, infection at or near the place of application, a blood disorder or a liver disease. It is advised to not apply this medicine on open wounds, burns, or broken or inflamed skin. Avoid its contact with the eyes, ears or mouth.

This medicine has a few side effects including burning, itching, whitening, swelling or skin rash at application site, cough, difficulty in swallowing, large, hives on the eyelids, lips, face or tongue, severe dizziness, shortness of breath, stuffy nose, tightness in the chest, troubled breathing and wheezing.

The recommended dose for adults and teenagers is 1 to 2.5 gm, applied as a thick layer to the skin area. Dosage for children is based on their body weight and must be determined by doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the uses of Numbex Cream

    • Arrhythmia

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    What are the side effects of Numbex Cream ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    Key highlights of Numbex Cream

    • Is It safe with alcohol?

      No interaction found

    • Are there any pregnancy warnings?

      Manforce staylong gel is probably safe to use during pregnancy.
      Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Manforce staylong gel is probably safe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

    • Does this affect kidney function?

      Caution should be used in patients with impaired renal function.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

    How does this medication work?

    Numbex Cream is a local anaesthetic that works by inhibiting depolarisation of the voltage gated sodium channel and stabilising the neuronal membrane. This leads to a decrease in the permeability of the membrane which reduces the influx of sodium required to conduct impulses.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Neurologist before using this medicine.

      References

      • Prilocaine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/prilocaine

      • Prilocaine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00750

      • PRILOCAINE ointment,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=PRILOCAINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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