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Overview

O2H Tablet

Banned
Manufacturer :  Medley Pharmaceuticals
Medicine Composition :  Ofloxacin, Ornidazole
Prescription vs OTC : Prescription by Doctor not required

About O2H Tablet

O2H Tablet is a combination medication primarily prescribed for treating diarrhoea and/or dysentery. It comprises antibacterial and antiamoebic drugs that fight against parasitic and bacterial infections. It is very effective in treating infectious conditions due to its dual-action.

This medication inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infections. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects after taking this medication. Some people are more likely to face harmful side effects if they also suffer from other conditions like brain disorders, seizures, heart conditions, myasthenia gravis, epilepsy, tendonitis, bone disorders and problems of the joints.

It is advisable to inform your doctor about the above-mentioned conditions beforehand if he/she recommends you taking this medicine. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic since it can lead to harmful consequences.

    What are the uses of O2H Tablet

    • Infectious Diarrhea

    • Dysentery

    What are the contraindications of O2H Tablet ?

    What are the side effects of O2H Tablet ?

    • Abdominal Pain

    • Joint Pain

    • Black Or Tarry Stools

    • Fever With Chills

    • Chest Tightness

    • Running Nose

    • Memory Impairment

    • Nervousness

    • Agitation

    • Disorientation

    Key highlights of O2H Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 12 to 20 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on the baby. Use only if clearly needed under the supervision of the doctor.

    What are the substitutes for O2H Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as O2H Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    This medicine is a combination of Ofloxacin and Ornidazole belonging to the class antibacterial and antiamoebic. Thus the medication follows a dual mechanism to produce its action. Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death. Secondly, it works by seeping into the cells of the bacteria and/or protozoa through diffusion and damaging DNA and other critical biomolecules through the formation of reactive nitro radicals.

      FAQs about O2H Tablet

      • Ques : What is O2h tablet?

        Ans : O2H is a medication which has Ofloxacin and Ornidazole as active elements present in it.

      • Ques : What is the use of O2h tablet?

        Ans : The medication is used for the treatment and prevention from conditions such as infectious diarrhoea and dysentery.

      • Ques : What are the side effects of O2h tablet?

        Ans : Tiredness, Dizziness, Headache, Photosensitivity, Hallucination, Sinus tachycardia, Insomnia, Seizures, Severe itching of the skin, Abdominal pain, Diarrhoea, Eosinophilia and Vaginitis are possible side-effects which may occur.

      • Ques : Are there any specific contraindications associated with the use of O2H?

        Ans : The use of O2h tablet is considered to be harmful to patients with known allergy to ofloxacin or to ornidazole or any medicine which belongs to the quinolone or nitroimidazole group of antimicrobial agents.

      • Ques : How long do I need to use o2h tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor.

      • Ques : At what frequency do I need to use o2h tablet?

        Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication.

      • Ques : Should I use o2h tablet empty stomach, before food or after food?

        Ans : The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach.

      • Ques : What are the instructions for the storage and disposal of o2h tablet?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above that, can cause an inadequate effect. Protect it from moisture and light.

      References

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • Ornidazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ornidazole

      • Ofloxacin- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 09 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB01165

      • Ornidazole- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 09 May 2019]. Available from:

        https://www.drugbank.ca/drugs/DB13026

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Vishwas Madhav ThakurMD-HRM, AFIH, PGDMLS, MBBS, MD-HMGeneral Physician
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