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Overview

Oflox Oz 200 Mg/500 Mg Tablet

Banned
Manufacturer :  Cipla Ltd
Medicine Composition :  Ofloxacin, Ornidazole
Prescription vs OTC : Prescription by Doctor not required

About Oflox Oz 200 Mg/500 Mg Tablet

Oflox Oz 200 Mg/500 Mg Tablet is a combination medication primarily prescribed for treating diarrhoea and/or dysentery. It comprises antibacterial and antiamoebic drugs that fight against parasitic and bacterial infections. It is very effective in treating infectious conditions due to its dual-action.

This medication inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infections. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects after taking this medication. Some people are more likely to face harmful side effects if they also suffer from other conditions like brain disorders, seizures, heart conditions, myasthenia gravis, epilepsy, tendonitis, bone disorders and problems of the joints.

It is advisable to inform your doctor about the above-mentioned conditions beforehand if he/she recommends you taking this medicine. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic since it can lead to harmful consequences.

Take per recommended schedule; complete full course of therapy and do not skip doses. Take on an empty stomach (1 hour before or 2 hours after meals, dairy products, antacids, or other medication).

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). Symptoms of Oflox Oz 200 Mg/500 Mg Tablet overdose include acute renal failure, seizures, nausea, vomiting. Treatment includes GI decontamination, if possible, and supportive care

    What are the uses of Oflox Oz 200 Mg/500 Mg Tablet

    • Severe Diarrhea

    • Infectious Diarrhea

    • Dysentery

    What are the contraindications of Oflox Oz 200 Mg/500 Mg Tablet ?

    What are the side effects of Oflox Oz 200 Mg/500 Mg Tablet ?

    • Abdominal Pain

    • Joint Pain

    • Fever With Chills

    • Numbness Of The Hands

    • Running Nose

    • Loss Of Appetite

    • Dizziness

    • Headache

    • Memory Impairment

    • Nervousness

    • Agitation

    • Disorientation

    Key highlights of Oflox Oz 200 Mg/500 Mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 24 hours.

    • What is the onset of action?

      The peak effect of the medicine can be seen after 1 to 3 hours of its administration.

    • Are there any pregnancy warnings?

      It is not recommended to be taken by pregnant women, it may cause mild effect to the fetus.

    • Is it habit forming?

      It is not known to have any habit forming tendencies.

    • Are there any breast-feeding warnings?

      It is not recommended to be taken by breastfeeding women, it may cause mild effect to the infant.

    • Is It safe with alcohol?

      The consumption of alcohol while taking this medicine is not safe as it may intensify the side effects like dizziness, confusion, headache etc.

    • Is it safe to drive while on this medicine?

      It is advised to avoid driving after taking Tablet as it causes side effects like confusion, dizziness, drowsiness, headache etc.

    • Does this affect kidney function?

      The use of medicine is known to have mild effect on the function of the kidney. If the patient is suffering from any kidney impairment, it is recommended to inform the doctor about the same before taking this drug.

    • Does this affect liver function?

      The use of Oflox Oz is known to have mild effect on the function of the liver.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    This medicine is a combination of Ofloxacin and Ornidazole belonging to the class antibacterial and antiamoebic. Thus the medication follows a dual mechanism to produce its action. Firstly, it works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death. Secondly, it works by seeping into the cells of the bacteria and/or protozoa through diffusion and damaging DNA and other critical biomolecules through the formation of reactive nitro radicals.

      What are the interactions of Oflox Oz 200 Mg/500 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Decreased effect: Decreased absorption with antacids containing aluminum, magnesium, and/or calcium (by up to 98% if given at the same time), iron, vitamins with minerals, mineral supplements, sucralfate, or didanosine; fluoroquinolones may be decreased by antineoplastic agents
        • Increased toxicity/serum levels: Quinolones cause increased caffeine, warfarin, cyclosporine, procainamide, and possibly theophylline levels. Cimetidine and probenecid increase quinolone levels.
      • Interaction with Disease

        Use with caution in patients with epilepsy or other CNS diseases which could predispose seizures; use with caution in patients with renal impairment; failure to respond to an ophthalmic antibiotic after 2-3 days may indicate the presence of resistant organisms, or another causative agent; use caution with systemic preparation in children <18 years of age due to association of other quinolones with transient arthropathy; has rarely caused ruptured tendons (discontinue immediately with signs of inflammation or tendon pain).

      FAQs about Oflox Oz 200 Mg/500 Mg Tablet

      • Ques : What is Oflox Oz 200 Mg/500 Mg Tablet?

        Ans : It is a combination medication which has Ofloxacin and Ornidazole as active elements present in it. This tablet performs its action by inhibits the infections caused by bacteria and restricts the growth of microorganism.

      • Ques : What are the side effects for Oflox Oz 200 Mg/500 Mg Tablet?

        Ans : Side effects of consuming the Oflox Oz tablet are Vomiting, Allergic skin reaction, Abdominal pain, Dizziness, Feeling of Tiredness, Nausea, Abnormal taste, etc.

      • Ques : How long do I need to use Oflox Oz 200 Mg/500 Mg Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : Is Oflox Oz 200 Mg/500 Mg Tablet a painkiller?

        Ans : No, this is not a painkiller medication. It belongs to the group of antibiotic medications.

      • Ques : Can Oflox Oz 200 Mg/500 Mg Tablet be taken empty stomach?

        Ans : No, it is not advised to take tablet on an empty stomach as it may lead to stomach issues. Take this medication after meals.

      • Ques : Can I take a higher than the recommended dose of Oflox Oz 200 Mg/500 Mg Tablet?

        Ans : No, patient is advised to take medicine as prescribed by doctor. Consuming overdose of this medication may cause toxicity and severe side effects.

      • Ques : Are there any specific contraindications associated with the use of Oflox Oz 200 Mg/500 Mg Tablet?

        Ans : It is contraindicated to the medication that contains ofloxacin, quinolone and ornidazole as active ingredients. Patients who are allergic to these medications are advised not to consume this medication.

      References

      • [Internet]. CiplaMed. 2018 [cited 5 March 2018]. Available from:

        https://ciplamed.com/content/oflox-oz-tablets

      • Ofloxacin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 17 February 2017]. Available from:

        https://medlineplus.gov/druginfo/meds/a691005.html

      • Ornidazole | C7H10ClN3O3 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 1 June 2017]. Available from:

        https://pubchem.ncbi.nlm.nih.gov/compound/28061#section=Top

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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