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Overview

Orasep 8% w/v/5

Manufacturer :  Elan Pharma India Pvt Ltd
Medicine Composition :  Choline Salicylate, Tannic Acid
Prescription vs OTC : Prescription by Doctor required

About Orasep 8% w/v/5

Orasep 8% w/v/5 is used in the treatment of mouth ulcers. Patients who are allergic to Orasep 8% w/v/5 or any of the ingredients of the gel or oral solution should not consume this drug before consulting the doctor.

Orasep 8% w/v/5 is also employed for temporary relief of pain of rheumatoid arthritis, rheumatic fever, osteoarthritis, and other conditions for which oral salicylates are recommended

It is also useful in patients in which there is difficulty in administering doses in a tablet or capsule dosage form, because of the liquid dosage form.

You must not apply this drug on open wounds. Don’t use the oral gel with children or adolescents because some studies show a link between salicylate use and Reye’s syndrome (affects the brain, liver and may be fatal).

Immediately consult your doctor if there is no improvement found in pain after using this drug for 7 to 14 days. Immediately take medical help if you have symptoms of stomach bleeding such as black, bloody, or coughing up blood or vomit that looks like coffee grounds.

Symptoms of overdose include tinnitus, vomiting, acute renal failure, hyperthermia, irritability, seizures, coma, metabolic acidosis. For acute ingestions, determine serum salicylate levels 6 hours after ingestion; the "Done" nomogram may be helpful for estimating the severity of aspirin poisoning and directing treatment using serum salicylate levels.

Treatment should also be based upon symptomatology. Toxic symptoms and corresponding treatments are as follows:

  • Overdose: Induce emesis with ipecac, and/or lavage with saline, followed with activated charcoal.
  • Dehydration: I.V. fluids with KCl (no D5W only).
  • Metabolic acidosis (must be treated): Sodium bicarbonate.
  • Hyperthermia: Cooling blankets or sponge baths.
  • Coagulopathy/hemorrhage: Vitamin K I.V.
  • Hypoglycemia (with coma, seizures, or change in mental status): Dextrose 25 g I.V.
  • Seizures: Diazepam 5-10 mg I.V.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the uses of Orasep 8% w/v/5

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the contraindications of Orasep 8% w/v/5 ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the side effects of Orasep 8% w/v/5 ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    Key highlights of Orasep 8% w/v/5

    • How long is the duration of effect?

      It may differ from person to person. You should consult about it with the doctor to get the suitable dosage prescriptions.

    • What is the onset of action?

      The action of this drug will be initiated within 2 hours after its administration.

    • Are there any pregnancy warnings?

      Pregnant women are advised to consult a doctor before consuming this drug.

    • Is it habit forming?

      No, the medicine is not habit-forming or addictive.

    • Are there any breast-feeding warnings?

      Lactating mothers are advised to take medical help before consuming this medication.

    • Is it safe to drive while on this medicine?

      It is advisable that you do not indulge in driving while on this medication since there is a possibility of you experiencing drowsy or calm and thus affecting your driving skills.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Avoid use in severe renal impairment. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      No relevant information is available.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the substitutes for Orasep 8% w/v/5 ?

    Below is the list of medicines, which have the same composition, strength and form as Orasep 8% w/v/5 , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      It is advisable that you do not miss a dosage since there is just one dose per day. Consume the missed dosage as soon as you remember.

    • Are there any overdose instructions?

      In case of an overdose, you may experience side effects like restlessness, anxiety, confusion or dizziness. In such cases, make sure that you consult a doctor with immediate effect.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    Where is the Orasep 8% w/v/5 approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    How does this medication work?

    It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). It also acts on the hypothalamus heat-regulating centre to reduce fever and blocks the generation of pain impulses.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

      What are the interactions of Orasep 8% w/v/5 ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        Orasep 8% w/v/5 administration leads to false-negative results for Clinistix® urine test; false-positive results with Clinitest®.
      • Interaction with Medicine

        • Decreased effect with antacids; ACE-inhibitor effects may be decreased by concurrent therapy with NSAIDS.
        • Increased effect of warfarin.
      • Interaction with Food

        Take with food or milk to minimize GI distress.
      • Interaction with Disease

        Use with caution in patients with impaired renal function, dehydration, erosive gastritis, or peptic ulcer; avoid use in patients with suspected varicella or influenza (salicylates have been associated with Reye's syndrome in children <16 years of age when used to treat symptoms of chickenpox or the flu).

      FAQs about Orasep 8% w/v/5

      • Ques : Does Orasep 8% w/v/5 cause Salicylate poisoning?

        Ans : The excessive use of Orasep 8% w/v/5 causes Salicylate poisoning. It is important to keep checks of signs and symptoms while on this medication and report any unknown change to your doctor.

      • Ques : Is Orasep 8% w/v/5 safe for use in children?

        Ans : Orasep 8% w/v/5 should be used with caution in children below the age of 16, additionally, there are contradictory results of efficacy and safety for use in infants.

      • Ques : How is Orasep 8% w/v/5 administered?

        Ans : Orasep 8% w/v/5 is administered orally, as instructed by the doctor.

      • Ques : What are the storage instructions of Orasep 8% w/v/5?

        Ans : Orasep 8% w/v/5 is stored at room temperature in darkness and out of reach of children.

      • Ques : Is Orasep 8% w/v/5 safe for use in patients with influenza?

        Ans : Orasep 8% w/v/5 should be used with caution, especially with children, as it maximizes the risk of adverse infections. It is advised to closely monitor the patient while on this medication.

      • Ques : Is it okay to smoke while taking Orasep 8% w/v/5?

        Ans : It is advised to not smoke with Orasep 8% w/v/5 as it may worsen the symptoms.

      References

      • Choline Salicylate-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 16 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/choline%20salicylate

      • Choline Salicylate-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 16 June 2022].Available from:

        https://go.drugbank.com/drugs/DB14006

      • LIDOCAINE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 16 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=LIDOCAINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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