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Overview

Pacitane 2 MG Tablet

Manufacturer :  Pfizer Ltd
Medicine Composition :  Trihexyphenidyl
Prescription vs OTC : Prescription by Doctor not required

About Pacitane 2 MG Tablet

Pacitane 2 MG Tablet is known to be an anticholinergic, thus it effectively relaxes some muscles of the body by stalling nerve impulses. The drug is used in the treatment of Parkinson’s disease and other conditions with similar symptoms and also for the treatment of drug-induced extrapyramidal effects.

Doctor’s generally do not recommend this medicine to patients who may be allergic to components present in it or patients who have problems like angle closure glaucoma, bowel and stomach issues, heart issues, an oesophagus that has narrowed or blockage of the urinary tract.

Certain medical conditions can reduce the effectiveness of the drug or create complications with the treatment. Thus before you start taking Pacitane 2 MG Tablet provide your doctor a detailed medical history, and ensure that it includes the health issues you currently have and related medicines you are taking.

Pregnant women or women who are planning to have a baby should also inform their doctor before taking this drug. The same applies for breast feeding women. It is best that you tell your medical practitioner about any kidney or liver problems you suffer from as well.

Pacitane 2 MG Tablet should be taken orally, either before a meal or after. If you mouth becomes extremely dry after you take the tablet, it is recommended that you take your dose before food. Although patients who suffer from nausea are generally advised to take the drug after food.

Like all medicines, even Pacitane 2 MG Tablet results in some side effects. You may suffer from some minor side effects like constipation, blurry vision, dryness of the mouth, feeling sleepy, increased sensitivity to light and headache.

Although major side effects are very rare, immediate medical aid should be sought if they do occur. For instance get in touch with your doctor if you experience chest pain, problems with swallowing food, problems while urinating or develop fever accompanied with chills.

Take exactly as directed; with meals if GI upset occurs, before meals if dry mouth occurs, after eating if drooling or if nausea occurs. Take at the same time each day. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake); avoid before taking medication.

Do not use alcohol and all prescription or OTC sedatives or CNS depressants without consulting prescriber. You may experience drowsiness, confusion, or vision changes (use caution when driving, climbing stairs, or engaging in tasks requiring alertness until response to drug is known).

    What are the uses of Pacitane 2 MG Tablet

    What are the contraindications of Pacitane 2 MG Tablet ?

    What are the side effects of Pacitane 2 MG Tablet ?

    Key highlights of Pacitane 2 MG Tablet

    • How long is the duration of effect?

      The effect of Pacitane lasts for 6 to 12 hours a day.

    • What is the onset of action?

      The onset of action of the medicine starts after 1 hour of the consumption of the drug.

    • Is it habit forming?

      Consuming Pacitane is not habit forming.

    • Is It safe with alcohol?

      Consult your doctor before consuming liquor.

    • Are there any pregnancy warnings?

      The drug is unsafe for use in pregnancy.

    • Are there any breast-feeding warnings?

      Pacitane is not prescribed during breastfeeding.

    • Is it safe to drive while on this medicine?

      It is safe to drive while using the medication.

    • Does this affect kidney function?

      Pacitane may affect kidney function. Limited information is available regarding its use in patients with kidney disease. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Pacitane may affect liver function. Limited information is available regarding its use in patients with liver disease. Kindly consult your doctor before taking it.

    What are the substitutes for Pacitane 2 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Pacitane 2 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      In case you miss a dose, take it as soon as you can remember unless it is almost time for the consumption of the next dose.

    • Are there any overdose instructions?

      The doctor must be immediately informed in the event of overdose.

    How does this medication work?

    Trihexyphenidyl belongs to anticholinergics. It works by blocking the cholinergic activity in the central nervous system and reduces the body secretions, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle. It also increases the dopamine which is used for smooth muscle movement.

      What are the interactions of Pacitane 2 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Medicine

        • Decreased effect: May increase gastric degradation of levodopa and decrease the amount of levodopa absorbed by delaying gastric emptying; the opposite may be true for digoxin.
        • Therapeutic effects of cholinergic agents (tacrine, donepezil) and neuroleptics may be antagonized.
        • Increased toxicity: Central and/or peripheral anticholinergic syndrome can occur when administered with amantadine, rimantadine, narcotic analgesics, phenothiazines and other antipsychotics (especially with high anticholinergic activity), tricyclic antidepressants, quinidine and some other antiarrhythmics, and antihistamines.
      • Interaction with Disease

        Elderly patients require strict dosage regulation. Use with caution in patients with tachycardia, cardiac arrhythmias, hypertension, hypotension, prostatic hypertrophy or any tendency toward urinary retention, liver or kidney disorders, and obstructive disease of the GI or GU tract. May exacerbate mental symptoms when used to treat extrapyramidal reactions. When given in large doses or to susceptible patients, may cause weakness. Does not improve symptoms of tardive dyskinesias.

      FAQs about Pacitane 2 MG Tablet

      • Ques : What is Pacitane 2 MG Tablet?

        Ans : This is a medication which has Trihexyphenidyl as an active element present in it. This medicine performs its action by obstructing the action of a chemical on the nerves.

      • Ques : What are the uses of Pacitane 2 MG Tablet?

        Ans : This drug is used to treat Parkinson's Disease, Drug-Induced Extrapyramidal Symptoms etc.

      • Ques : What are the Side Effects of Pacitane 2 MG Tablet?

        Ans : Side effects include abdominal pain, constipation, etc.

      • Ques : What are the instructions for storage and disposal Pacitane 2 MG Tablet?

        Ans : It should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

      • Ques : Can Pacitane 2 MG Tablet be used for movement disorder and nervous system breakdown?

        Ans : Yes, this can be used to treat movement disorder and nervous system breakdown. These are among the most common reported uses for this medicine.

      • Ques : How long do I need to use Pacitane 2 MG Tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

      • Ques : At what frequency do I need to use Pacitane 2 MG Tablet?

        Ans : It is generally used twice or thrice a day, as the time interval upto which this medication has an impact, is around 6 to 12 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Pacitane 2 MG Tablet empty stomach, before food or after food?

        Ans : This medication is common to consume orally and the salts involved in this medication react properly, if it is taken with the food. If you take it with an empty stomach, it may cause stomach upset. Please consult the doctor before use.

      References

      • TRIHEXYPHENIDYL HYDROCHLORIDE - trihexyphenidyl hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2010 [Cited 26 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b7e4200c-feff-4537-aad1-cf9989fd8c14

      • Trihexyphenidyl- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 26 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/trihexyphenidyl

      • Trihexyphenidyl 2mg Tablets- EMC [Internet]. www.medicines.org.uk. 2019 [Cited 26 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/5271/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Utsav NandwanaMBBS Bachelor of Medicine and Bachelor of Surgery, MBBSGeneral Physician
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