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Overview

Pegtoline Plus Syrup

Banned
Manufacturer :  Libra Drugs India
Medicine Composition :  Metronidazole, Norfloxacin
Prescription vs OTC : Prescription by Doctor required

About Pegtoline Plus Syrup

Pegtoline Plus Syrup is antibacterial and antifungal. It is used either on its own or in combination to cure inflammatory diseases, endocarditis, dracunculiasis, giardiasis, trichomoniasis and amebiasis. It can only treat certain parasitic and bacterial infections of the vagina, respiratory tract, skin and joints. Pegtoline Plus Syrup is sold under the trade name of Flagyl and Flagyl ER.

Like all medicines there are certain associated side effects with the usage of Pegtoline Plus Syrup which are dizziness, headache, upset stomach, abdominal pain, vomiting, nausea, reduced appetite, either diarrhea or constipation, blurred vision, clouded thoughts, fever, irritability, aggression, depression, difficulty speaking and breathing, skin rash or redness, a burning sensation, blisters, sore throat, darkening of the urine, rapid or irregular heartbeat and mouth ulcers to name a few. Should the side effects continue or worsen overtime, contact your health care provider right away.

Before starting Pegtoline Plus Syrup treatment you should consult with your doctor and tell him/her if you have any allergies, have liver, nerve disorders or blood cell disorders, stomach or intestinal infections such as Crohn’s disease, epilepsy or other kinds of seizures, if you’re pregnant or are planning to become pregnant. In case you are nursing a baby the use of Pegtoline Plus Syrup is not recommended as it may pass into breast milk and cause harm to the infant.

Pegtoline Plus Syrup comes in both capsule and tablet form. The dosage will be prescribed by your doctor determining your age, gender, overall health and the severity of your condition. The usual dosage in adults for a bacterial infection is about 7.5 mg orally every 6 hours over a period of 7-10 days. And if you are taking it by infusion then the advised dose is about 15 mg once for 1 hour daily over a period of 7-10 days as well. Dose for other treatments vary from one person to another. In case of drug overdose, seek medical attention immediately.

    What are the uses of Pegtoline Plus Syrup

    • Amebiasis

      Pegtoline Plus Syrup is used in the amebiasis which is a parasitic infection that affects the intestine and amebic liver abscess caused by Entamoeba histolytica.

    • Trichomoniasis

      Pegtoline Plus Syrup is used in the treatment of trichomoniasis which is a sexually transmitted disease caused by Trichomonas vaginalis.

    • Bacterial Vaginosis

      Pegtoline Plus Syrup is used in the treatment of overgrowth of bacteria in the vagina caused by Lactobacillus species.

    • Bacterial Infections

      Pegtoline Plus Syrup is used to treat the infectins caused by bacteria in blood, lungs, genital areas caused by Bacteroides fragilis and Clostridium species.

    • Surgical Prophylaxis

      Pegtoline Plus Syrup is used to treat infections that may cause after surgery.

    What are the contraindications of Pegtoline Plus Syrup ?

    • Allergy

      Not recommended in patients with known allergy to Pegtoline Plus Syrup or other nitroimidazoles.

    What are the side effects of Pegtoline Plus Syrup ?

    Key highlights of Pegtoline Plus Syrup

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 24 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1 to 2 hours.

    • Are there any pregnancy warnings?

      This medicine is not recommended in the first trimester of pregnancy to treat bacterial vaginosis and trichomoniasis. It can be used in the second and third trimesters of pregnancy only if clearly needed.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is known to excreted through the breastmilk. It is used in breastfeeding women only if clearly needed. Breastfeeding should be avoided for 24 hours after single-dose maternal treatment. Monitoring of candidal infections and diarrhea is necessary.

    What are the substitutes for Pegtoline Plus Syrup ?

    Below is the list of medicines, which have the same composition, strength and form as Pegtoline Plus Syrup , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of Pegtoline Plus Syrup, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    Pegtoline Plus Syrup belongs to the class anthelmintics. It enters into the organism and forms the free radical. A concentration gradient is created in the organism due to alteration in the molecule and promotes the influx of the molecule. Thus, the free radical and the altered molecule will interfere with the DNA synthesis and stops the growth of the organism.

      What are the interactions of Pegtoline Plus Syrup ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Ethanol

        Consumption of alcohol is not recommended in patients with Pegtoline Plus Syrup. Any symptoms of the fast heartbeat, warmth, headache, and breathing difficulty should be reported to the doctor.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Warfarin

        Pegtoline Plus Syrup may increase the concentration of warfarin and increase the risk of bleeding. Inform the doctor if you have any bleeding disorder. Any symptoms of unusual bleeding, blood in stools, headache, and dizziness should be reported to the doctor. An alternate class of medicine should be considered based on the clinical condition.

        Ethinyl Estradiol

        The desired effect of contraceptive pills will not be achieved if these medicines are taken together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Atorvastatin

        These medicines may increase the risk of nerve damage if given together. Any symptoms of numbness, tingling or burning sensation in feet, hands should be informed to the doctor. An alternate medicine should be considered based on the clinical condition.

        Disulfiram

        Pegtoline Plus Syrup is not recommended in patients receiving disulfiram due to the risk of confusion and psychotic symptoms. Inform the doctor if you are receiving these medications. Any symptoms of change in behavior, irritation, and altered coordination should be reported to the doctor.
      • Interaction with Disease

        Disease

        Information not available.
      • Interaction with Food

        Food

        Information not available.

      FAQs about Pegtoline Plus Syrup

      • Ques : What is Pegtoline Plus Syrup?

        Ans : Metronidazole is a medication which has Metronidazole as an active elements present in it. This is an antibiotic medication that performs its action by preventing the growth of bacterias and parasites. Metronidazole is used to treat conditions such as common cold, flu, bacterial and parasitic infections. This medication treats controls liver, skin, joints, brain and respiratory tract infections.

      • Ques : What are the uses of Pegtoline Plus Syrup?

        Ans : Metronidazole is a medication, which is used for the treatment and prevention from viral and parasitic infections. It also prevents bacterial infections such as cold, cough, flu and vaginal infections. It also controls liver, skin, joints, brain and respiratory tract infections. The patient should inform the doctor about any ongoing medications and treatment before using Metronidazole to avoid undesirable effects.

      • Ques : What are the Side Effects of Pegtoline Plus Syrup?

        Ans : Metronidazole is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Metronidazole which are diarrhea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness and mouth ulcer.

      • Ques : What are the instructions for storage and disposal Pegtoline Plus Syrup?

        Ans : Metronidazole should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is important to dispose expired and unused medications properly to avoid adverse effects.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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