Pexep Cr 12.5Mg Tablet

Pexep Cr 12.5Mg Tablet is an antidepressant that is used in the treatment of various mental disorders such as OCD, depression, anxiety, post-traumatic stress disorder (PTSD). In some cases, Pexep Cr 12.5Mg Tablet is also used in the treatment of hot flashes and night sweats that comes from menopause.

On using Pexep Cr 12.5Mg Tablet the common side effects that you may experience are dryness of the mouth, reduced appetite, drowsiness, insomnia, problems with ejaculation, agitation, chest pain, skin rash, difficulty in breathing, lightheadedness, dizziness, fast or irregular heartbeat, fever, restlessness, speech problems, blurred vision, acidity, abdominal pain, cough, darkening of the urine and shakiness.

Notify your doctor immediately if you have suicidal thoughts, hallucinations, coordination issues and convulsion. Before using this medicine, tell your doctor if you have any of the following conditions:

• Pregnant, or are planning to become pregnant,
• Breastfeeding a baby.
• Low sodium levels.
• History of seizures or epilepsy.
• History of glaucoma.
• Liver, heart or kidney diseases.
• Taking any prescriptive or over the counter drugs, herbal medications or dietary supplements. As interaction with certain drugs especially anti-inflammatory ones such as NSAID may cause certain harmful reactions.

The dosage for Pexep Cr 12.5Mg Tablet will be prescribed by your doctor as per your medical history, age, gender, the current medical condition and what reactions you have after the first course of medicine. Pexep Cr 12.5Mg Tablet is available in both tablet and liquid form. Generally the usual dose in adults is about 20 mg (tablet/suspension) orally once in a day.

Take exactly as directed (do not increase dose or frequency); may take 2-3 weeks to achieve desired results; may cause physical and/or psychological dependence. Take in the morning to reduce the incidence of insomnia.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). Report persistent insomnia or excessive daytime sedation; muscle cramping, tremors, weakness, or change in gait; chest pain, palpitations, or rapid heartbeat.

Symptoms of Paroxetine overdose include nausea, vomiting, drowsiness, sinus tachycardia, and dilated pupils. There are no specific antidotes, following attempts at decontamination, treatment is supportive and symptomatic; forced diuresis, dialysis, and hemoperfusion are unlikely to be beneficial.

• Depression

• Social Anxiety Disorder

• Panic Disorder

• Premenstrual Dysphoric Disorder

• Obsessive Compulsive Disorder (Ocd)

• Post Traumatic Stress Disorder (Ptsd)

• Anxiety

• Postmenopausal Symptoms

• Monoamine oxidase inhibitors (MAOI)

• Thioridazine

• Pimozide

• Allergy

• Headache

• Dizziness

• Insomnia

• Nausea

• Constipation

• Diarrhoea

• Ejaculation Disorder

• Weakness

• Sweating

• Palpitations

• Rash

• Vasodilation

• Nervousness

• Anxiety

• Decreased Libido

• Delayed Ejaculation

• Anorexia

• Flatulence

• Vomiting

• Dyspepsia

• Tremor

• How long is the duration of effect?

  The time for which this medication remains effective in the body is not clearly established. Dosing, duration and the condition for which this medication is given determine the effective time duration.

• What is the onset of action?

  The effect of this medication is cumulative and may take months to show. It varies depending on the intended use and the dosing.

• Are there any pregnancy warnings?

  In case of pregnancy, you must consult the doctor.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Use of this medicine by breastfeeding women is not recommended unless necessary. If necessary, your doctor may advise you to stop breastfeeding before treatment with this medicine is initiated.

• Is It safe with alcohol?

  It is found that consumption of alcohol is unsafe with this medicine.

• Is it safe to drive while on this medicine?

  This medicine may cause side effects which affects the alertness of the patient. Thus driving must be avoided if you are taking this medicine.

• Does this affect kidney function?

  Caution in patients with kidney disease is needed. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

• Does this affect liver function?

  Caution in patients with liver disease is needed. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

Below is the list of medicines, which have the same composition, strength and form as Pexep Cr 12.5Mg Tablet , and hence can be used as its substitute.

• Parox 12.5Mg Tablet Cr

  Tripada Biotec Pvt Ltd

• Parocen 12.5Mg Tablet Er

  USV Ltd

• Parot 12.5Mg Tablet Cr

  ZDL(Zodiacal) Pharmaceutics Pvt.Ltd

• Paropex 12.5Mg Tablet Cr

  Shilpex Pharmysis

• Paxgem 12.5Mg Tablet Xr

  La Pharmaceuticals

• Xodep 12.5Mg Tablet Cr

  Ivy Healthcare

• Xepar 12.5Mg Tablet Sr

  Consern Pharma P Ltd

• Pxn 12.5Mg Tablet Sr

  Tas Med India Pvt Ltd

• Paxi 12.5Mg Tablet Cr

  OSR Pharmaceuticals Pvt Ltd

• PEXPEN 12.5MG TABLET CR

  Aspen Pharma

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If the next scheduled dose is less than 4 hours away, then the missed dose should be skipped.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose with this medicine is suspected.

It works by selectively inhibiting the reuptake of serotonin. This results in higher concentrations of serotonin in the brain.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving vehicles and operating heavy machinery while using this medicine.

• Interaction with Lab Test

  Pexep Cr 12.5Mg Tablet may alter LTFs of the patient taking it.

• Interaction with Medicine

  • Pexep Cr 12.5Mg Tablet may cause hyponatremia. Additive hyponatremic effects may be seen with combined use of a loop diuretic (bumetanide, furosemide, torsemide); monitor for hyponatremia.
  • Pexep Cr 12.5Mg Tablet inhibits the reuptake of serotonin. Combined use with a serotonin agonist (buspirone) may cause serotonin syndrome.
  • Pexep Cr 12.5Mg Tablet inhibits the metabolism of dextromethorphan; visual hallucinations occurred in a patient receiving this combination; monitor for serotonin syndrome.
  • Pexep Cr 12.5Mg Tablet may inhibit the metabolism of haloperidol and cause extrapyramidal symptoms (EPS); monitor patients for EPS if combination is utilized.
  • Pexep Cr 12.5Mg Tablet should not be used with nonselective MAOIs (isocarboxazid, phenelzine). Fatal reactions have been reported. Wait two weeks after stopping fluoxetine before starting an MAOI and two weeks after stopping an MAOI before starting fluoxetine.
  • Pexep Cr 12.5Mg Tablet inhibits the reuptake of serotonin; combined use with other drugs which inhibit the reuptake (nefazodone, sibutramine) may cause serotonin syndrome. Monitor patient for altered response with nefazodone; avoid sibutramine combination.
  • Pexep Cr 12.5Mg Tablet has been reported to cause mania or hypertension when combined with selegiline; this combination is best avoided.
  • Pexep Cr 12.5Mg Tablet combined with tramadol (serotonergic effects) may cause serotonin syndrome; monitor.
  • Pexep Cr 12.5Mg Tablet may alter the hypoprothombinemic response to warfarin; monitor.
  • Cimetidine may reduce the first-pass metabolism of Pexep Cr 12.5Mg Tablet resulting in elevated paroxetine serum concentrations; consider an alternative H2 antagonist.

• Interaction with Disease

  • Potential for a severe reaction, when used with MAO inhibitors - serotonin syndrome (hyperthermia, muscular rigidity, mental status changes/agitation, autonomic instability), may occur.
  • May precipitate a shift to mania or hypomania in patients with bipolar disease.
  • Has a low potential to impair cognitive or motor performance - caution operating hazardous machinery or driving.
  • Low potential for sedation or anticholinergic effects relative to cyclic antidepressants.
  • Use caution in patients with depression, particularly if suicidal risk may be present.
  • Use caution in patients with a previous seizure disorder or condition predisposing to seizures such as brain damage, alcoholism, or concurrent therapy with other drugs which lower the seizure threshold.
  • Use with caution in patients with hepatic or dysfunction and in elderly patients. May cause hyponatremia/SIADH.
  • Use with caution in patients at risk of bleeding or receiving anticoagulant therapy - may cause impairment in platelet aggregation.
  • Use with caution in patients with renal insufficiency or other concurrent illness (due to limited experience).
  • May cause or exacerbate sexual dysfunction.

• Ques : What is Pexep Cr 12.5Mg Tablet?

  Ans : This tablet belongs to a medicine group that carry Paroxetine. It is used for the treatment of Depression, Panic attacks and Anxiety riots. It increases the growth of Chemical Serotonin in the brain. It treats Post traumatic stress and Premenstrual Dysphoric disorders.

• Ques : What is the use of Pexep Cr 12.5Mg Tablet?

  Ans : It is used to treat Post traumatic Stress and Premenstrual Dysphoric disorders. It is also used to control Social anxiety and Panic attacks. Pexep helps to cure Depression and Obsessive Compulsive disorders.

• Ques : What are the side effects of Pexep Cr 12.5Mg Tablet?

  Ans : It has many common side effects such as irregular heartbeat, Constipation, dizziness and shaking of feet or hands. There are some serious side effects of this medicine like Suicidal thinking, Changes in sex drive, increased blood cholesterol and maniac reactions.

• Ques : For what treatment Pexep Cr 12.5Mg Tablet used for?

  Ans : It is used to treat Depression and Anxiety disorders. It is also used to control Postmenopausal symptoms. This tablet helps to improve obsessive compulsive disorders and panic attacks.This medication is also helpful in Premenstrual dysphoric disorder.

• Ques : How long do I need to use Pexep Cr 12.5Mg Tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 3 months. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

• Ques : At what frequency do I need to use Pexep Cr 12.5Mg Tablet?

  Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use Pexep Cr 12.5Mg Tablet empty stomach, before food or after food?

  Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for the storage and disposal of Pexep Cr 12.5Mg Tablet?

  Ans : This medication contains salts which are suitable to store between 15 to 30 c temperature. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

• Paroxetine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 15 May 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paroxetine

• Paroxetine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 15 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00715

• PAROXETINE- paroxetine hydrochloride tablet, film coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 15 May 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=08320ea3-8f93-6f04-5d1c-f69af3eb5a81

• Important Information About Paroxetine- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 15 May 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-paroxetine/