Piperaquine

Piperaquine is used to treat and improve the condition of people suffering from malaria and is a type of antimalarial . It is a bisquinoline that was first developed in the 1960s and was used in China and also in Indo-China as a type of prophylaxis and for treatment over a period of the next 20 years.

There was a decline in its usage in the 1980s as artemisinin-based antimalarials came into being. Research is going on if it can be used by combining it with artemisinin. In recent times this medication and dihydroartemisinin were developed and used in combination with each other. It replaced the use of chloroquine in China for the treatment of falciparum malaria in the late 1970s.

This medication works by chemically interfering with the intraparasitic heme detoxification that prevents the dimerization process. It then leads to the formation of a malarial pigment known as hemozoin.

You should consult your doctor before taking this medication if you are:

• planning on becoming pregnant
• breastfeeding
• allergic to it or any ingredient used in it
• have any medical conditions
• taking any supplements or medication
• fungal or bacterial infection
• have alcohol dependency
• drug addiction
• depression
• malaria affecting the brain
• any heart conditions

Currently this medication is available as tablets and should be taken orally. It contains 320mg of Piperaquine in combination with 40mg of dihydroartemisinin. The adult dosage is 3 tablets per day that you should take after equal intervals of time and should continue for the time duration prescribed by your doctor.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Malaria

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Palpitations

• Altered Heart Rate

• Cough

• Shortness Of Breath

• Nausea

• Vomiting

• Weakness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  This medication may be unsafe to use during pregnancy.

• Are there any breast-feeding warnings?

  This medication is probably unsafe to use during breastfeeding. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult a doctor before consuming the drug.

• What is the onset of action?

  The time required to produce its action is not established clinically.

• How long is the duration of effect?

  The time for which this medicine will remain active within the body after its administration is not clinically established.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

• Are there any missed dose instructions?

  If you miss a dose of this medication, please consult your doctor.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Piperaquine as ingredient

• Synriam 150/750Mg Tablet

  Sun Pharmaceutical Industries Ltd

• Faldp Capsule

  Zuventus Healthcare Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medication is used to treat malaria. A bisquinoline compound, it stops the formation of the malarial pigment hemozoin by chemically inhibiting heme crystallization process of the malarial parasites.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Food

  Food

  Avoid concomitant intake of fatty food along with this medicine, as presence of fat increase the absorption of the medicine. Increased absorption will cause adverse effects (Irregular heart beat) in some patients with high severity.

• Ques : What is Piperaquine?

  Ans : This medication is a type of antimalarial drug used to treat, provide relief and improve the health condition of people suffering from malaria.

• Ques : How long do I need to use Piperaquine before I see improvement in my condition?

  Ans : You need to take this medicine according to the prescription of the doctor.

• Ques : At what frequency do I need to use Piperaquine?

  Ans : The adult dosage is 3 tablets per day that you should take after equal intervals of time.

• Ques : Should I use Piperaquine empty stomach, before food or after food?

  Ans : This medication should be taken empty stomach or as prescribed schedule.

• Ques : What are the instructions for the storage and disposal of Piperaquine

  Ans : This capsule should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Piperaquine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 5 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/piperaquine

• Piperaquine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 5 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB13941

• Piperaquine: Bioanalysis, drug metabolism and pharmacokinetics- Joel Tärning [Internet]. gupea.ub.gu.se 2007 [cited 5 December 2019]. Available from:

  https://gupea.ub.gu.se/bitstream/2077/7196/1/1.%20Ramber%C3%A4ttelse.pdf