Polydex Eye/Ear Drops

Polydex Eye/Ear Drops is a combination of two medicines: Chloramphenicol and Dexamethasone. Chloramphenicol is an antibiotic which stops bacterial growth in the eye/ear by preventing the synthesis of essential proteins required by the bacteria to carry out vital functions. Dexamethasone is a steroid. It blocks the production of certain chemical messengers (Prostaglandins) that make the eye/ear red, swollen and itchy.

This medication is used to treat conditions involving swelling (inflammation) of the eyes and to treat or prevent bacterial eye infections. This product contains neomycin and polymyxin, antibiotics that work by stopping the growth of bacteria. It also contains dexamethasone, an anti-inflammatory corticosteroid that works by reducing swelling.

This medication treats/prevents only bacterial eye infections. It will not work for other types of eye infections and may worsen them (e.g., infections caused by viruses, fungi, mycobacteria). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

• Eye Infection

• Ear Infection (Otitis Media)

• Pregnancy

• Application Site Irritation

• Burning Sensation

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 6 to 8 hours after an oral dose and 2 hours after an intravenous dose.

• What is the onset of action?

  The effect of this medicine can be observed in 30 to 60 minutes after an oral dose, 30 minutes after an intramuscular dose and 5 min after an intravenous dose.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for women who are breastfeeding.

Below is the list of medicines, which have the same composition, strength and form as Polydex Eye/Ear Drops , and hence can be used as its substitute.

• Pyrimon Eye Drop

  FDC Ltd

• D Chlorex Eye Drop

  Torque Pharmaceuticals Pvt Ltd

• Opthodex Eye Drop

  Optho Remedies Pvt Ltd

• Decol C Eye Drop

  Intas Pharmaceuticals Ltd

• Visomer Eye Drop

  Indiana Opthalmics

• Clodil Eye Drop

  Search Orbis Pharmaceuticals

• Missed Dose instructions

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Polydex Eye/Ear Drops is a loop diuretic that inhibiting water reabsorption in the nephrons. This is done by blocking the sodium-potassium-chloride cotransporter (NKCC2) in the ascending limb of the loop of Henle. This in turn prevents sodium, potassium and chloride from being absorbed which increases urine output.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Consumption of alcohol is not recommended while you are taking this medicine. It may increase the risk of dizziness and fainting. Avoid performing activities that need mental alertness like operating machinery or driving a vehicle.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Nonsteroidal anti-inflammatory drugs

  Use of Polydex Eye/Ear Drops with nonsteroidal anti-inflammatory drugs like diclofenac, aceclofenac may increase the risk of kidney injury. Drink adequate amount of water to prevent dehydration. Close monitoring of blood pressure and kidney function are necessary. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.

  Aminoglycoside antibiotics

  Polydex Eye/Ear Drops is not recommended with aminoglycoside antibiotics like amikacin, gentamycin, streptomycin due to the increase in the risk of kidney injury and hearing problems. Inform the doctor if you experience any symptoms of hearing loss, dizziness, sudden weight gain. An alternate medicine should be considered based on the clinical condition.

  Antidepressants

  Escitalopram may lower the blood sodium levels if coadministered with diuretics like Polydex Eye/Ear Drops. Inform the doctor if you may have symptoms like dizziness, lightheadedness after taking these medicines. Consider regular monitoring of blood pressure and sodium level.

• Interaction with Disease

  Diabetes

  Taking this medicine may increase the blood glucose levels. Close monitoring of blood glucose levels is necessary. Inform the doctor about your medical condition. Suitable dose adjustments should be made based on the clinical condition.

• Interaction with Food

  Food

  Information not available.