Powergesic MR 500 mg/50 mg/325 mg Tablet

Powergesic MR Tablet is a combination medicine used for the treatment of muscle spasm pain usually associated with musculoskeletal conditions. This medicine contains muscle relaxant in combination with NSAID.

It works by blocking pain sensations or nerve impulses that are sent to the brain. Powergesic MR 500 mg/50 mg/325 mg Tablet when used together with rest and physical therapy can treat skeletal muscle conditions such as injury or pain.

Avoid using Powergesic MR if you are allergic to it or if you are taking sodium oxybate. Inform your doctor if you have or you are:

• pregnant
• Planning to become pregnant
• Breast-feeding
• liver problems
• Blood disease called porphyria.

Stop using Powergesic MR 500 mg/50 mg/325 mg Tablet and consult your doctor if you experience any serious side effects including black, bloody, or tarry stools, nausea, itching, fainting, upper stomach pain, dark urine, loss of appetite and clay-coloured stools.

Powergesic MR Tab is to be taken by mouth with or without food. Taking it with food reduces the risk of stomach upset. Do not take in this medicine in larger or smaller amounts or for longer than recommended. Follow your doctor’s prescription carefully to ensure complete safety.

• Muscle Spasm

• Relieve Muscle Spasm

• Chronic Musculoskeletal Pain

• Allergy

• Gastrointestinal Bleeding

• Pregnancy

• Nursing Mothers

• Coronary Artery Bypass Surgery (Cabg)

• Severe Liver/Kidney Damage

• Diarrhoea

• Nausea

• Indigestion

• Rash

• Itching

• Headache

• Dizziness

• Insomnia

• Blurred Vision

• Loss Of Appetite

• Is It safe with alcohol?

  Powergesic MR Tab may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Powergesic MR Tab should be avoided by pregnant women unless suggested by the doctor. The effect of this medicine on fetus is not clearly established and hence, doctor consultation is recommended before consumption.

• Are there any breast-feeding warnings?

  Please consult your doctor before taking this tablet if you are breastfeeding.

• Is it safe to drive while on this medicine?

  Patients should not drive or operate machinery if they get affected symptoms like dizziness, drowsiness, fatigue, visual disturbances.

• Does this affect kidney function?

  Powergesic MR medicine should be used with caution in patients with underlying kidney disease. Please Consult your doctor.

• Does this affect liver function?

  Use of this medicine should be avoided in patients with underlying liver disease.

• What is the onset of action?

  The action of Powergesic MR 500 mg/50 mg/325 mg Tablet will be initiated within 60 minutes after its administration.

• How long is the duration of effect?

  Powergesic MR 500 mg/50 mg/325 mg Tablet will remain active for about 3-4 hrs after when its action is initiated.

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Powergesic MR tablet is a muscle relaxant that is used to treat the muscle spasms and the pain caused by the same. The medicine inhibits an enzyme named Cyclooxygenase which is responsible for the formation of prostaglandin. Prostaglandin is a major contributor to the process of inflammation and pain sensation in the body.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  You must not consume alcohol as it can lead to excessive drowsiness and dizziness, thus making you lose the ability to function properly or to your full potential.

• Interaction with Medicine

  Powergesic MR medicine can react with multiple tablets and cause harmful side effects. Carbamazepine, Phenytoin, Ramipril and Aspirin are some of the tablets that can cause moderate side effects when used along with Powergesic MR 500 mg/50 mg/325 mg Tablet. Methotrexate, Sodium Nitrite, Prilocaine, Adefovir, Apixaban and Ketorolac are the medicines that can cause severe side effects. Therefore, you must discuss all the medications you take before starting the prescription period.

• Interaction with Disease

  Powergesic MR Tab can aggravate the symptoms of multiple diseases like asthma, gastrointestinal toxicity, skin rash, heart attack and stroke, bleeding disorders, liver impairment, fluid retention and edema. Therefore, it is important that you consult a doctor before the intake of this medicine and stick to the dosages mentioned in the prescription. Doing otherwise can cause any of the mentioned diseases.

• Ques : What is Powergesic MR 500 mg/50 mg/325 mg Tablet?

  Ans : Powergesic MR Tablet functions as a muscle relaxer. It contains Chlorzoxazone, Diclofenac Sodium and Paracetamol as active ingredients.

• Ques : What is Powergesic MR 500 mg/50 mg/325 mg Tablet used for?

  Ans : Powergesic MR Tablet is used for the treatment and prevention from conditions and symptoms of diseases like joint pain, muscle cramps, rheumatoid arthritis, muscle spasm, and ear pain.

• Ques : What are the side effects of Powergesic MR 500 mg/50 mg/325 mg Tablet?

  Ans : Side effects include dizziness, severe liver toxicity, allergic reactions, the feeling of sickness, and skin reddening.

• Ques : What are the instructions for storage and disposal of Powergesic MR 500 mg/50 mg/325 mg Tablet?

  Ans : Powergesic MR should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : How long do I need to use Powergesic MR 500 mg/50 mg/325 mg Tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 3 days to 1 week, before noticing an improvement in the condition.

• Ques : At what frequency do I need to use Powergesic MR 500 mg/50 mg/325 mg Tablet?

  Ans : Powergesic MR Tab is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication.

• Ques : Should I use Powergesic MR 500 mg/50 mg/325 mg Tablet empty stomach, before food or after food?

  Ans : The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach.

• Chlorzoxazone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/chlorzoxazone

• CHLORZOXAZONE- chlorzoxazone tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 23 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2f05e8e2-616f-475b-ac9f-c42e1a5dbe81

• Diclofenac- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/diclofenac

• Diclofenac- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00586

• Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/paracetamol