Pregaba NT 75 mg/10 mg Tablet

Pregaba NT Tablet is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

Pregaba NT Tab is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

• Angiotensin- converting enzyme inhibitors
• Benzodiazepines or narcotic pain medicines
• Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

• If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
• If you have improper kidney functioning or are on dialysis.
• If you have a history of angioedema.
• If you are pregnant, planning to be pregnant or are breastfeeding.
• If you take any other medicines, dietary supplements or herbal preparations.
• If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

• Neuropathic Pain

• Diabetic Peripheral Neuropathy

• Postherpetic Neuralgia

• Allergy

• Myocardial Infarction

• Dizziness

• Drowsiness

• Peripheral Edema

• Nausea

• Blurred Vision

• Dry Mouth

• Weight Gain

• Is It safe with alcohol?

  Pregaba NT tablet may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Pregaba NT may be unsafe to use during pregnancy.

• Are there any breast-feeding warnings?

  It is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.

• Is it safe to drive while on this medicine?

  Pregaba NT medicine may affect your alertness which may affect your ability to drive.

• Does this affect kidney function?

  Pregaba NT Tab should be used with caution in patients with kidney disease.

• Does this affect liver function?

  Pregaba NT tablet is probably safe to use in patients with liver disease.

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected. Symptoms of overdose may include agitation, mental confusion, excessive drowsiness.

Pregaba NT Tab is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Alcohol consumption should be limited during the course of medication.

• Interaction with Medicine

  Medicine

  Do not use this tablet in combination with Lorazepam, Pioglitazone, Ramipril and Oxycodone.

• Interaction with Disease

  Disease

  Patients who suffer from Angioedema should exercise caution while taking this tablet.

• Ques : What is Pregaba NT Tablet?

  Ans : Pregaba NT Tab is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

• Ques : How long do I need to use Pregaba NT 75 mg/10 mg Tablet before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : What are the side effects of Pregaba NT 75 MG Tablet?

  Ans : Side effects of Pregaba NT Tab include:

  1. Nausea
  2. Irritability
  3. Muscle cramps
  4. Fatigue
  5. Blurred vision
  6. Clumsiness
  7. Memory impairment
  8. Sore throat
  9. Hypersensitivity
  10. Joint pain
  11. Vomiting
  12. Tremor
  13. Drowsiness
  14. Increased appetite
  15. Slows conduction
  16. Peripheral neuropathy
  17. Rashes and Hypersensitivity reactions.

• Ques : Can Pregaba NT Tablet be used for nerve damage pain and anxiety disorder in adults?

  Ans : Yes, Pregaba NT is a medication which can be used to treat conditions such as nerve damage pain and anxiety disorder in adults.

• Ques : How long do I need to use Pregaba NT 75 mg 10 mg tablet before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by Pregaba NT medication to reach its peak effect is around 1 week to 3 months, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action.

• Ques : At what frequency do I need to use pregaba nt 75 mg 10 mg tablet?

  Ans : Pregaba NT medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication.

• Ques : Should I use Pregaba NT Tablet empty stomach, before food or after food?

  Ans : The action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for the storage and disposal of pregaba nt 75 mg 10 mg tablet?

  Ans : Pregaba NT medicine contains salts which are suitable to store only at room temperature, as keeping this medication above that, can cause an inadequate effect. Protect it from moisture and light.

• Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

• Nortriptyline-EMC [Internet]. www.medicines.org.uk. 2017 [Cited 24 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/4090/smpc

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-pregabalin/